SI3590942T1 - Inhibitor površinskega antigena virusa hepatitisa B - Google Patents
Inhibitor površinskega antigena virusa hepatitisa BInfo
- Publication number
- SI3590942T1 SI3590942T1 SI201830376T SI201830376T SI3590942T1 SI 3590942 T1 SI3590942 T1 SI 3590942T1 SI 201830376 T SI201830376 T SI 201830376T SI 201830376 T SI201830376 T SI 201830376T SI 3590942 T1 SI3590942 T1 SI 3590942T1
- Authority
- SI
- Slovenia
- Prior art keywords
- hepatitis
- surface antigen
- virus surface
- antigen inhibitor
- inhibitor
- Prior art date
Links
- 241000700721 Hepatitis B virus Species 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710138275 | 2017-03-09 | ||
| EP18763490.2A EP3590942B1 (en) | 2017-03-09 | 2018-03-09 | Hepatitis b virus surface antigen inhibitor |
| PCT/CN2018/078581 WO2018161960A1 (zh) | 2017-03-09 | 2018-03-09 | 乙型肝炎病毒表面抗原抑制剂 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3590942T1 true SI3590942T1 (sl) | 2021-11-30 |
Family
ID=63447286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201830376T SI3590942T1 (sl) | 2017-03-09 | 2018-03-09 | Inhibitor površinskega antigena virusa hepatitisa B |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US11008331B2 (sl) |
| EP (1) | EP3590942B1 (sl) |
| JP (1) | JP6783424B2 (sl) |
| KR (1) | KR102087397B1 (sl) |
| CN (1) | CN109071564B (sl) |
| AU (1) | AU2018232071B2 (sl) |
| BR (1) | BR112019018650B1 (sl) |
| CA (1) | CA3055442C (sl) |
| DK (1) | DK3590942T3 (sl) |
| EA (1) | EA038122B9 (sl) |
| ES (1) | ES2879930T3 (sl) |
| HR (1) | HRP20211331T1 (sl) |
| HU (1) | HUE055170T2 (sl) |
| IL (1) | IL269142B (sl) |
| LT (1) | LT3590942T (sl) |
| MX (1) | MX374497B (sl) |
| MY (1) | MY174224A (sl) |
| PH (1) | PH12019502052B1 (sl) |
| PL (1) | PL3590942T3 (sl) |
| PT (1) | PT3590942T (sl) |
| RS (1) | RS62094B1 (sl) |
| SG (1) | SG11201908101YA (sl) |
| SI (1) | SI3590942T1 (sl) |
| WO (1) | WO2018161960A1 (sl) |
| ZA (1) | ZA201906252B (sl) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10738035B2 (en) | 2015-05-13 | 2020-08-11 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
| MX384836B (es) | 2016-03-07 | 2025-03-14 | Enanta Pharm Inc | Agentes antivirales contra la hepatitis b |
| CN110066278B (zh) | 2017-06-01 | 2021-06-08 | 广东东阳光药业有限公司 | 稠合三环类化合物及其在药物中的应用 |
| EA202090514A1 (ru) | 2017-08-28 | 2020-06-24 | Энанта Фармасьютикалс, Инк. | Противовирусное средство против гепатита в |
| WO2019143902A2 (en) | 2018-01-22 | 2019-07-25 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
| WO2019169539A1 (en) * | 2018-03-05 | 2019-09-12 | Pharmaresources (Shanghai) Co., Ltd. | Novel oxa-and aza-tricyclic 4-pyridone-3-carboxylic acid for treatment and prophylaxis of hepatitis b virus infection |
| WO2019191166A1 (en) | 2018-03-29 | 2019-10-03 | Enanta Pharmaceuticals, Inc. | Hepatitis b antiviral agents |
| US12128044B2 (en) | 2018-08-28 | 2024-10-29 | Sunshine Lake Pharma Co., Ltd. | Fused tricyclic compounds and uses thereof in medicine |
| US20210330678A1 (en) * | 2018-09-05 | 2021-10-28 | Children`S Medical Center Corporation | Papd5 inhibitors and methods of use thereof |
| JP2022500466A (ja) | 2018-09-21 | 2022-01-04 | エナンタ ファーマシューティカルズ インコーポレイテッド | 抗ウイルス剤としての官能化複素環 |
| CN110964023B (zh) | 2018-09-30 | 2022-12-27 | 广东东阳光药业有限公司 | 稠合四环类化合物及其在药物中的应用 |
| SG11202105007TA (en) | 2018-11-21 | 2021-06-29 | Enanta Pharm Inc | Functionalized heterocycles as antiviral agents |
| US11236111B2 (en) | 2019-06-03 | 2022-02-01 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
| US11760755B2 (en) | 2019-06-04 | 2023-09-19 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
| WO2020247575A1 (en) | 2019-06-04 | 2020-12-10 | Enanta Pharmaceuticals, Inc. | Hepatitis b antiviral agents |
| WO2021007488A1 (en) | 2019-07-11 | 2021-01-14 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
| WO2021055425A2 (en) | 2019-09-17 | 2021-03-25 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
| WO2021052447A1 (zh) * | 2019-09-19 | 2021-03-25 | 福建广生堂药业股份有限公司 | 一种乙肝表面抗原抑制剂的晶型及其应用 |
| US11802125B2 (en) | 2020-03-16 | 2023-10-31 | Enanta Pharmaceuticals, Inc. | Functionalized heterocyclic compounds as antiviral agents |
| JP7706475B2 (ja) * | 2020-05-15 | 2025-07-11 | 福建▲広▼生中霖生物科技有限公司 | 三環式化合物を含む組み合わせ及びｈｂｖ治療薬物の製造におけるその使用 |
| WO2021228222A1 (zh) * | 2020-05-15 | 2021-11-18 | 福建广生堂药业股份有限公司 | 用于治疗乙肝的组合 |
| JP2023550260A (ja) * | 2020-11-25 | 2023-12-01 | エフ． ホフマン－ラ ロシュ アーゲー | Ｂ型肝炎ウイルス感染症の処置および予防のための芳香族スピロ環アミド誘導体 |
| WO2022152019A1 (zh) * | 2021-01-15 | 2022-07-21 | 福建广生中霖生物科技有限公司 | 一种手性噁嗪类化合物的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130251647A1 (en) * | 2011-09-20 | 2013-09-26 | Basf Se | Low molecular weight modulators of the cold menthol receptor trpm8 and use thereof |
| CN103450184A (zh) | 2012-05-29 | 2013-12-18 | 上海壹志医药科技有限公司 | 斯氏紫堇碱衍生物的盐 |
| CA2931329A1 (en) * | 2014-01-30 | 2015-08-06 | F. Hoffmann-La Roche Ag | Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection |
| HK1244281B (zh) * | 2015-02-11 | 2020-02-07 | F. Hoffmann-La Roche Ag | 治疗和预防乙型肝炎病毒感染的2-氧代-6，7-二氢苯并[a]喹嗪-3-甲酸衍生物 |
| JP6598974B2 (ja) * | 2015-07-21 | 2019-10-30 | エフ．ホフマン−ラ ロシュ アーゲー | Ｂ型肝炎ウイルス感染症の治療および予防のための新規な三環式４−ピリドン−３−カルボン酸誘導体 |
| CN107835813B (zh) | 2015-07-28 | 2020-04-24 | 豪夫迈·罗氏有限公司 | 用于治疗和预防乙型肝炎病毒感染的6,7-二氢吡啶并[2,1-a]酞嗪-2-酮类化合物 |
| CN107759585A (zh) * | 2016-07-29 | 2018-03-06 | 银杏树药业(苏州)有限公司 | 一种异喹啉类化合物及其药用组合物和作为抗病毒药物的应用 |
-
2018
- 2018-03-09 EP EP18763490.2A patent/EP3590942B1/en active Active
- 2018-03-09 HU HUE18763490A patent/HUE055170T2/hu unknown
- 2018-03-09 CA CA3055442A patent/CA3055442C/en active Active
- 2018-03-09 BR BR112019018650-6A patent/BR112019018650B1/pt active IP Right Grant
- 2018-03-09 HR HRP20211331TT patent/HRP20211331T1/hr unknown
- 2018-03-09 EA EA201992082A patent/EA038122B9/ru unknown
- 2018-03-09 US US16/491,769 patent/US11008331B2/en active Active
- 2018-03-09 CN CN201880001647.2A patent/CN109071564B/zh active Active
- 2018-03-09 MX MX2019010736A patent/MX374497B/es active IP Right Grant
- 2018-03-09 PL PL18763490T patent/PL3590942T3/pl unknown
- 2018-03-09 ES ES18763490T patent/ES2879930T3/es active Active
- 2018-03-09 WO PCT/CN2018/078581 patent/WO2018161960A1/zh not_active Ceased
- 2018-03-09 PH PH1/2019/502052A patent/PH12019502052B1/en unknown
- 2018-03-09 DK DK18763490.2T patent/DK3590942T3/da active
- 2018-03-09 KR KR1020197029437A patent/KR102087397B1/ko active Active
- 2018-03-09 MY MYPI2019005107A patent/MY174224A/en unknown
- 2018-03-09 SG SG11201908101Y patent/SG11201908101YA/en unknown
- 2018-03-09 RS RS20210851A patent/RS62094B1/sr unknown
- 2018-03-09 JP JP2019548977A patent/JP6783424B2/ja active Active
- 2018-03-09 PT PT187634902T patent/PT3590942T/pt unknown
- 2018-03-09 SI SI201830376T patent/SI3590942T1/sl unknown
- 2018-03-09 LT LTEPPCT/CN2018/078581T patent/LT3590942T/lt unknown
- 2018-03-09 AU AU2018232071A patent/AU2018232071B2/en active Active
-
2019
- 2019-09-05 IL IL269142A patent/IL269142B/en active IP Right Grant
- 2019-09-20 ZA ZA2019/06252A patent/ZA201906252B/en unknown
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