SI3551293T1 - RNAZA za izboljšano odkrivanje mikrobov in testiranje protimikrobne dovzetnosti - Google Patents
RNAZA za izboljšano odkrivanje mikrobov in testiranje protimikrobne dovzetnostiInfo
- Publication number
- SI3551293T1 SI3551293T1 SI201731143T SI201731143T SI3551293T1 SI 3551293 T1 SI3551293 T1 SI 3551293T1 SI 201731143 T SI201731143 T SI 201731143T SI 201731143 T SI201731143 T SI 201731143T SI 3551293 T1 SI3551293 T1 SI 3551293T1
- Authority
- SI
- Slovenia
- Prior art keywords
- rnase
- susceptibility testing
- antimicrobial susceptibility
- microbial detection
- improved microbial
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
- C12Q2521/327—RNAse, e.g. RNAseH
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
- G01N2333/922—Ribonucleases (RNAses); Deoxyribonucleases (DNAses)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662430785P | 2016-12-06 | 2016-12-06 | |
| PCT/US2017/064774 WO2018111630A2 (en) | 2016-12-06 | 2017-12-05 | Rnase for improved microbial detection and antimicrobial susceptibility testing |
| EP17880407.6A EP3551293B1 (en) | 2016-12-06 | 2017-12-05 | Rnase for improved microbial detection and antimicrobial susceptibility testing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3551293T1 true SI3551293T1 (sl) | 2022-06-30 |
Family
ID=62559120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201731143T SI3551293T1 (sl) | 2016-12-06 | 2017-12-05 | RNAZA za izboljšano odkrivanje mikrobov in testiranje protimikrobne dovzetnosti |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20190376116A1 (sl) |
| EP (1) | EP3551293B1 (sl) |
| JP (1) | JP7246316B2 (sl) |
| CA (1) | CA3046001A1 (sl) |
| DK (1) | DK3551293T3 (sl) |
| ES (1) | ES2913212T3 (sl) |
| IL (1) | IL267098B2 (sl) |
| LT (1) | LT3551293T (sl) |
| PL (1) | PL3551293T3 (sl) |
| PT (1) | PT3551293T (sl) |
| SI (1) | SI3551293T1 (sl) |
| WO (1) | WO2018111630A2 (sl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018058078A1 (en) | 2016-09-23 | 2018-03-29 | California Institute Of Technology | Digital quantification of dna replication and/or chromosome segregation based determination of antimicrobial susceptibility |
| US11827944B2 (en) | 2017-10-11 | 2023-11-28 | California Institute Of Technology | Antibiotic susceptibility of microorganisms and related compositions, methods and systems |
| US12448655B2 (en) | 2017-10-11 | 2025-10-21 | California Institute Of Technology | Antibiotic susceptibility of microorganisms and related methods and systems |
| CA3115289A1 (en) * | 2018-10-04 | 2020-04-09 | First Light Diagnostics, Inc. | Test cartridges |
| CN116814818A (zh) * | 2019-07-22 | 2023-09-29 | 四川大学华西医院 | 一种区分抗生素耐药的肺炎克雷伯菌的装置及方法 |
| WO2021021782A1 (en) * | 2019-07-29 | 2021-02-04 | Microbedx Inc. | Method for antibiotic susceptibility testing of blood samples |
| CN112816580B (zh) * | 2020-12-30 | 2023-09-05 | 海南海神同洲制药有限公司 | 一种硝酸舍他康唑栓的杂质检测方法 |
| CN112881575A (zh) * | 2021-02-09 | 2021-06-01 | 江南大学 | 以α-脂霉素作为检测、诊断高血压的标志物制备相应检测工具的应用 |
| US20220282304A1 (en) * | 2021-02-26 | 2022-09-08 | California Institute Of Technology | Same-sample antibiotic susceptibility test and related compositions, methods and systems |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040157219A1 (en) * | 2003-02-06 | 2004-08-12 | Jianrong Lou | Chemical treatment of biological samples for nucleic acid extraction and kits therefor |
| WO2012027302A2 (en) * | 2010-08-21 | 2012-03-01 | The Regents Of The University Of California | Systems and methods for detecting antibiotic resistance |
| AU2011374466B2 (en) * | 2011-07-29 | 2015-06-11 | Morinaga Milk Industry Co., Ltd. | Antimicrobial activity enhancing agent |
| US20130231261A1 (en) * | 2012-02-17 | 2013-09-05 | Institute For Systems Biology | Rnase h-based rna profiling |
| DK2844762T3 (en) * | 2012-05-04 | 2018-03-26 | Univ California | TESTING FOR ANTIBIOTIC SENSITIVITY USING PROBRIOSOMAL RNA PROBLEMS |
| JP6496727B2 (ja) * | 2013-07-23 | 2019-04-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California | ベータラクタム系抗生物質に対する感受性を迅速に判定するためのアムジノシリン |
| CN113943773A (zh) * | 2014-11-05 | 2022-01-18 | 加州理工学院 | 生物体对药物的响应的微流体测量 |
-
2017
- 2017-12-05 SI SI201731143T patent/SI3551293T1/sl unknown
- 2017-12-05 JP JP2019551254A patent/JP7246316B2/ja active Active
- 2017-12-05 CA CA3046001A patent/CA3046001A1/en active Pending
- 2017-12-05 ES ES17880407T patent/ES2913212T3/es active Active
- 2017-12-05 EP EP17880407.6A patent/EP3551293B1/en active Active
- 2017-12-05 LT LTEPPCT/US2017/064774T patent/LT3551293T/lt unknown
- 2017-12-05 PT PT178804076T patent/PT3551293T/pt unknown
- 2017-12-05 PL PL17880407T patent/PL3551293T3/pl unknown
- 2017-12-05 US US16/466,746 patent/US20190376116A1/en not_active Abandoned
- 2017-12-05 IL IL267098A patent/IL267098B2/en unknown
- 2017-12-05 DK DK17880407.6T patent/DK3551293T3/da active
- 2017-12-05 WO PCT/US2017/064774 patent/WO2018111630A2/en not_active Ceased
-
2023
- 2023-08-21 US US18/452,765 patent/US20240068008A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3046001A1 (en) | 2018-06-21 |
| IL267098A (en) | 2019-08-29 |
| EP3551293A4 (en) | 2020-09-02 |
| IL267098B1 (en) | 2024-03-01 |
| US20240068008A1 (en) | 2024-02-29 |
| WO2018111630A3 (en) | 2018-09-20 |
| IL267098B2 (en) | 2024-07-01 |
| DK3551293T3 (da) | 2022-05-16 |
| WO2018111630A2 (en) | 2018-06-21 |
| ES2913212T3 (es) | 2022-06-01 |
| JP2020505943A (ja) | 2020-02-27 |
| PT3551293T (pt) | 2022-05-13 |
| EP3551293B1 (en) | 2022-02-09 |
| LT3551293T (lt) | 2022-05-25 |
| EP3551293A2 (en) | 2019-10-16 |
| PL3551293T3 (pl) | 2022-05-23 |
| US20190376116A1 (en) | 2019-12-12 |
| JP7246316B2 (ja) | 2023-03-27 |
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