SI3191489T1 - Pirolopirimidini za uporabo pri okužbi z virusom gripe - Google Patents
Pirolopirimidini za uporabo pri okužbi z virusom gripeInfo
- Publication number
- SI3191489T1 SI3191489T1 SI201531478T SI201531478T SI3191489T1 SI 3191489 T1 SI3191489 T1 SI 3191489T1 SI 201531478 T SI201531478 T SI 201531478T SI 201531478 T SI201531478 T SI 201531478T SI 3191489 T1 SI3191489 T1 SI 3191489T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pyrrolopyrimidines
- influenza virus
- virus infection
- infection
- influenza
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14183984 | 2014-09-08 | ||
| EP15760159.2A EP3191489B1 (en) | 2014-09-08 | 2015-09-07 | Pyrrolopyrimidines for use in influenza virus infection |
| PCT/EP2015/070316 WO2016037953A1 (en) | 2014-09-08 | 2015-09-07 | Pyrrolopyrimidines for use in influenza virus infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3191489T1 true SI3191489T1 (sl) | 2021-02-26 |
Family
ID=51535336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201531478T SI3191489T1 (sl) | 2014-09-08 | 2015-09-07 | Pirolopirimidini za uporabo pri okužbi z virusom gripe |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9932346B2 (sl) |
| EP (1) | EP3191489B1 (sl) |
| JP (1) | JP6718451B2 (sl) |
| KR (1) | KR102531340B1 (sl) |
| CN (1) | CN106661036B (sl) |
| AU (1) | AU2015314394A1 (sl) |
| BR (1) | BR112017004524A2 (sl) |
| CA (1) | CA2957475A1 (sl) |
| CL (1) | CL2017000533A1 (sl) |
| DK (1) | DK3191489T3 (sl) |
| EA (1) | EA201790571A1 (sl) |
| ES (1) | ES2860688T3 (sl) |
| HR (1) | HRP20210038T1 (sl) |
| HU (1) | HUE053595T2 (sl) |
| IL (1) | IL250955A0 (sl) |
| LT (1) | LT3191489T (sl) |
| MX (1) | MX2017002972A (sl) |
| PH (1) | PH12017500393A1 (sl) |
| SG (1) | SG11201701621YA (sl) |
| SI (1) | SI3191489T1 (sl) |
| WO (1) | WO2016037953A1 (sl) |
| ZA (1) | ZA201701643B (sl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201405826RA (en) | 2009-06-17 | 2014-12-30 | Vertex Pharma | Inhibitors of influenza viruses replication |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| EP3294735B8 (en) | 2015-05-13 | 2022-01-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インフルエンザウイルスの複製の阻害剤を調製する方法 |
| AU2016368317B2 (en) | 2015-12-09 | 2019-05-23 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication, application methods and uses thereof |
| KR20180099839A (ko) * | 2016-01-07 | 2018-09-05 | 얀센 사이언시즈 아일랜드 유씨 | 인플루엔자 바이러스 감염에서 사용하기 위한 작용화된 펜탄산 |
| WO2017133669A1 (en) * | 2016-02-05 | 2017-08-10 | Savira Pharmaceuticals Gmbh | 5, 7-diazaindole and 5, 7-diazaindazole derivatives and their use in the treatment, amelioration or prevention of influenza |
| WO2017133665A1 (en) * | 2016-02-05 | 2017-08-10 | Savira Pharmaceuticals Gmbh | 6,7-diazaindazole and 6,7-diazaindole derivatives and use in treatment, amelioration or prevention of influenza thereof |
| CN107759571B (zh) | 2016-08-16 | 2021-03-02 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其使用方法和用途 |
| CN106316886A (zh) * | 2016-08-24 | 2017-01-11 | 泰州精英化成医药科技有限公司 | 顺式‑3‑（叔丁氧羰基氨基）环己烷甲酸的制备方法 |
| CN109641868B (zh) * | 2016-08-30 | 2021-12-03 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其使用方法和用途 |
| US10987354B2 (en) | 2016-12-15 | 2021-04-27 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| JP7299837B2 (ja) | 2016-12-23 | 2023-06-28 | アクイナ ファーマシューティカルズ， インコーポレイテッド | 化合物、組成物、および使用方法 |
| WO2018127096A1 (en) | 2017-01-05 | 2018-07-12 | Sunshine Lake Pharma Co., Ltd. | Inhibitors of influenza virus replication and uses thereof |
| CN110446711B (zh) * | 2017-03-02 | 2022-02-15 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其用途 |
| CA3059449A1 (en) | 2017-04-24 | 2018-11-01 | Cocrystal Pharma, Inc. | Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication |
| CN108727369B (zh) * | 2017-04-25 | 2023-06-09 | 广东东阳光药业有限公司 | 流感病毒复制抑制剂及其用途 |
| CN120118069A (zh) * | 2023-12-08 | 2025-06-10 | 武汉人福创新药物研发中心有限公司 | Mrgprx2拮抗剂及用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080063809A (ko) * | 2005-09-30 | 2008-07-07 | 버텍스 파마슈티칼스 인코포레이티드 | 야누스 키나아제의 억제제로서 유용한 데아자퓨린 |
| SG10201405826RA (en) * | 2009-06-17 | 2014-12-30 | Vertex Pharma | Inhibitors of influenza viruses replication |
| EA026201B1 (ru) * | 2010-11-19 | 2017-03-31 | Инсайт Холдингс Корпорейшн | Циклобутилзамещенные производные пирролопиридина и пирролопиримидина как ингибиторы jak |
| RU2013132681A (ru) * | 2010-12-16 | 2015-01-27 | Вертекс Фармасьютикалз Инкорпорейтед | Ингибиторы репликации вирусов гриппа |
| CA2822062A1 (en) * | 2010-12-16 | 2012-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| UA118010C2 (uk) * | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
-
2015
- 2015-09-07 AU AU2015314394A patent/AU2015314394A1/en not_active Abandoned
- 2015-09-07 EA EA201790571A patent/EA201790571A1/ru unknown
- 2015-09-07 CN CN201580047970.XA patent/CN106661036B/zh not_active Expired - Fee Related
- 2015-09-07 MX MX2017002972A patent/MX2017002972A/es unknown
- 2015-09-07 BR BR112017004524A patent/BR112017004524A2/pt not_active IP Right Cessation
- 2015-09-07 DK DK15760159.2T patent/DK3191489T3/da active
- 2015-09-07 JP JP2017532206A patent/JP6718451B2/ja active Active
- 2015-09-07 LT LTEP15760159.2T patent/LT3191489T/lt unknown
- 2015-09-07 SI SI201531478T patent/SI3191489T1/sl unknown
- 2015-09-07 EP EP15760159.2A patent/EP3191489B1/en active Active
- 2015-09-07 US US15/509,474 patent/US9932346B2/en active Active
- 2015-09-07 SG SG11201701621YA patent/SG11201701621YA/en unknown
- 2015-09-07 HU HUE15760159A patent/HUE053595T2/hu unknown
- 2015-09-07 WO PCT/EP2015/070316 patent/WO2016037953A1/en not_active Ceased
- 2015-09-07 HR HRP20210038TT patent/HRP20210038T1/hr unknown
- 2015-09-07 KR KR1020177008672A patent/KR102531340B1/ko active Active
- 2015-09-07 CA CA2957475A patent/CA2957475A1/en not_active Abandoned
- 2015-09-07 ES ES15760159T patent/ES2860688T3/es active Active
-
2017
- 2017-03-02 PH PH12017500393A patent/PH12017500393A1/en unknown
- 2017-03-06 CL CL2017000533A patent/CL2017000533A1/es unknown
- 2017-03-06 IL IL250955A patent/IL250955A0/en unknown
- 2017-03-07 ZA ZA2017/01643A patent/ZA201701643B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUE053595T2 (hu) | 2021-07-28 |
| IL250955A0 (en) | 2017-04-30 |
| PH12017500393A1 (en) | 2017-07-17 |
| LT3191489T (lt) | 2021-01-25 |
| DK3191489T3 (da) | 2021-03-29 |
| EA201790571A1 (ru) | 2017-08-31 |
| CA2957475A1 (en) | 2016-03-17 |
| CL2017000533A1 (es) | 2017-10-06 |
| KR102531340B1 (ko) | 2023-05-10 |
| BR112017004524A2 (pt) | 2017-12-05 |
| US9932346B2 (en) | 2018-04-03 |
| CN106661036B (zh) | 2022-03-15 |
| ES2860688T3 (es) | 2021-10-05 |
| US20170253600A1 (en) | 2017-09-07 |
| WO2016037953A1 (en) | 2016-03-17 |
| ZA201701643B (en) | 2018-12-19 |
| AU2015314394A1 (en) | 2017-03-02 |
| SG11201701621YA (en) | 2017-03-30 |
| EP3191489A1 (en) | 2017-07-19 |
| ES2860688T8 (es) | 2022-01-18 |
| EP3191489B1 (en) | 2021-01-06 |
| JP2017527619A (ja) | 2017-09-21 |
| HRP20210038T1 (hr) | 2021-03-05 |
| CN106661036A (zh) | 2017-05-10 |
| JP6718451B2 (ja) | 2020-07-08 |
| MX2017002972A (es) | 2017-05-30 |
| KR20170054420A (ko) | 2017-05-17 |
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