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SI2913394T1 - Ko-diferenciacija in aktivacija monocitov iz alogenskih darovalcev za zagotovitev proinflamatornih dendričnih celic - Google Patents

Ko-diferenciacija in aktivacija monocitov iz alogenskih darovalcev za zagotovitev proinflamatornih dendričnih celic

Info

Publication number
SI2913394T1
SI2913394T1 SI201330281A SI201330281A SI2913394T1 SI 2913394 T1 SI2913394 T1 SI 2913394T1 SI 201330281 A SI201330281 A SI 201330281A SI 201330281 A SI201330281 A SI 201330281A SI 2913394 T1 SI2913394 T1 SI 2913394T1
Authority
SI
Slovenia
Prior art keywords
monocytes
differentiation
activation
dendritic cells
allogeneic donors
Prior art date
Application number
SI201330281A
Other languages
English (en)
Inventor
Alex Karlsson-Parra
Bengt Andersson
Original Assignee
Immunicum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunicum Ab filed Critical Immunicum Ab
Publication of SI2913394T1 publication Critical patent/SI2913394T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/15Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/40Nucleotides, nucleosides or bases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/22Colony stimulating factors (G-CSF, GM-CSF)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/2304Interleukin-4 (IL-4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/24Interferons [IFN]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
    • C12N2506/115Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells from monocytes, from macrophages

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201330281A 2012-12-18 2013-12-18 Ko-diferenciacija in aktivacija monocitov iz alogenskih darovalcev za zagotovitev proinflamatornih dendričnih celic SI2913394T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12197687 2012-12-18
EP15161369.2A EP2913394B1 (en) 2012-12-18 2013-12-18 Co-differentiation and activation of monocytes from allogeneic donors to provide pro-inflammatory dendritic cells

Publications (1)

Publication Number Publication Date
SI2913394T1 true SI2913394T1 (sl) 2017-01-31

Family

ID=47427250

Family Applications (2)

Application Number Title Priority Date Filing Date
SI201330281A SI2913394T1 (sl) 2012-12-18 2013-12-18 Ko-diferenciacija in aktivacija monocitov iz alogenskih darovalcev za zagotovitev proinflamatornih dendričnih celic
SI201330066T SI2788474T1 (sl) 2012-12-18 2013-12-18 Ko-diferenciacija monocitov iz alogenskih darovalcev

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI201330066T SI2788474T1 (sl) 2012-12-18 2013-12-18 Ko-diferenciacija monocitov iz alogenskih darovalcev

Country Status (16)

Country Link
US (2) US9714413B2 (sl)
EP (2) EP2788474B1 (sl)
JP (1) JP6529439B2 (sl)
KR (1) KR102148051B1 (sl)
CN (2) CN105452449B (sl)
AU (1) AU2013360793B2 (sl)
BR (1) BR112015014270B1 (sl)
CA (1) CA2895280C (sl)
DK (2) DK2788474T3 (sl)
ES (2) ES2591230T3 (sl)
HU (2) HUE028895T2 (sl)
MX (1) MX357491B (sl)
PL (2) PL2913394T3 (sl)
RU (1) RU2668816C2 (sl)
SI (2) SI2913394T1 (sl)
WO (1) WO2014096033A1 (sl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3460052B1 (en) 2017-09-20 2019-10-30 Immunicum AB Improved allogeneic dendritic cells for use in cancer treatment
US12329807B2 (en) 2018-01-18 2025-06-17 Meganano Biotech, Inc. Dead antigen stimulated immature heterogenous dendritic cells as therapeutics for diseases
CN108660125A (zh) * 2018-05-14 2018-10-16 武汉博百欧生物科技有限公司 一种从人体输血废弃物中提取中性粒细胞嗜天青颗粒的方法
US20220106566A1 (en) * 2019-01-22 2022-04-07 The Brigham And Women`S Hospital, Inc. Antigen-Presenting Neutrophil-Derived Dendritic Cells and Methods of Use Thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001051617A1 (en) * 2000-01-11 2001-07-19 Maxygen, Inc. Monocyte-derived dendritic cell subsets
AU2002326463A1 (en) * 2001-07-25 2003-02-17 Northwest Biotherapeutics, Inc. Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors
DK1509244T3 (da) 2002-06-06 2011-10-24 Immunicum Ab Ny fremgangsmåde og præparat til at producere en cellulær allogen vaccine
KR100585456B1 (ko) * 2003-09-30 2006-06-07 국립암센터 동종 종양-관련 항원이 탑재된 수지상세포, 이의 제조방법및 이를 유효성분으로 하는 암 치료용 백신 조성물
CA2504451A1 (en) * 2004-08-10 2006-02-10 Geron Corporation Dendritic cell vaccines for treating cancer made from embryonic stem cells
EP3072958A1 (en) * 2005-12-08 2016-09-28 NorthWest Biotherapeutics, Inc. Compositions and methods for inducing the activation of immature monocytic dendritic cells
EP1806395A1 (en) * 2006-01-06 2007-07-11 Stichting Sanquin Bloedvoorziening Maturation of dendritic cells
EP1840206A1 (en) * 2006-03-28 2007-10-03 Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh Compositions for the preparation of mature dendritic cells
BR112012009962A2 (pt) * 2009-10-27 2015-09-15 Immunicum Ab método para a proliferação de células tantígeno específicas.
HUE028352T2 (en) * 2010-02-10 2016-12-28 Immunicum Ab An improved composition for inhibiting tumor cell proliferation
CN103502439B (zh) * 2011-04-13 2016-10-12 因缪尼卡姆股份公司 用于抗原特异性t细胞增殖的方法
JP2014511704A (ja) * 2011-04-13 2014-05-19 イミュニカム・エイビイ T細胞のプライミングのための方法

Also Published As

Publication number Publication date
JP6529439B2 (ja) 2019-06-12
EP2913394B1 (en) 2016-06-22
CN110042081A (zh) 2019-07-23
MX357491B (es) 2018-07-11
BR112015014270B1 (pt) 2018-12-04
WO2014096033A1 (en) 2014-06-26
US9714413B2 (en) 2017-07-25
EP2913394A1 (en) 2015-09-02
EP2788474B1 (en) 2015-06-24
HUE028895T2 (en) 2017-02-28
ES2548229T3 (es) 2015-10-15
MX2015007800A (es) 2016-01-12
JP2016501529A (ja) 2016-01-21
RU2015119164A (ru) 2017-01-26
CN105452449B (zh) 2019-05-07
BR112015014270A2 (pt) 2015-11-03
US20170321189A1 (en) 2017-11-09
CN110042081B (zh) 2023-09-01
AU2013360793A1 (en) 2015-06-11
PL2913394T3 (pl) 2016-12-30
CN105452449A (zh) 2016-03-30
CA2895280C (en) 2021-04-06
CA2895280A1 (en) 2014-06-26
US20150329823A1 (en) 2015-11-19
PL2788474T3 (pl) 2015-12-31
DK2913394T3 (en) 2016-09-19
US10626371B2 (en) 2020-04-21
RU2668816C2 (ru) 2018-10-02
DK2788474T3 (en) 2015-09-28
KR20150122624A (ko) 2015-11-02
AU2013360793B2 (en) 2019-01-31
SI2788474T1 (sl) 2016-01-29
ES2591230T3 (es) 2016-11-25
EP2788474A1 (en) 2014-10-15
HUE027619T2 (en) 2016-10-28
KR102148051B1 (ko) 2020-08-25

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