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SI2766367T1 - 4-amino-3-fenilamino-6-fenilpirazol(3,4-D)primidinski derivati za zdravljenje virusnih okužb, zlasti pikornavirusnih okužb - Google Patents

4-amino-3-fenilamino-6-fenilpirazol(3,4-D)primidinski derivati za zdravljenje virusnih okužb, zlasti pikornavirusnih okužb

Info

Publication number
SI2766367T1
SI2766367T1 SI201232005T SI201232005T SI2766367T1 SI 2766367 T1 SI2766367 T1 SI 2766367T1 SI 201232005 T SI201232005 T SI 201232005T SI 201232005 T SI201232005 T SI 201232005T SI 2766367 T1 SI2766367 T1 SI 2766367T1
Authority
SI
Slovenia
Prior art keywords
infections
phenylpyrazolo
phenylamino
amino
treatment
Prior art date
Application number
SI201232005T
Other languages
English (en)
Inventor
Peter Wutzler
Michaela Schmidtke
Vadim Makarov
Original Assignee
Scandion Oncology A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE201110116373 external-priority patent/DE102011116373A1/de
Application filed by Scandion Oncology A/S filed Critical Scandion Oncology A/S
Publication of SI2766367T1 publication Critical patent/SI2766367T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201232005T 2011-10-14 2012-10-15 4-amino-3-fenilamino-6-fenilpirazol(3,4-D)primidinski derivati za zdravljenje virusnih okužb, zlasti pikornavirusnih okužb SI2766367T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE201110116373 DE102011116373A1 (de) 2011-10-14 2011-10-14 Methode zur Herstellung von 4-Amino-3-arylamino-6-arylpyrazolo[3, 4-d]pyrimidinen
DE102011116384 2011-10-20
PCT/EP2012/070403 WO2013053942A1 (de) 2011-10-14 2012-10-15 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidin-derivate, deren herstellung und deren verwendung als antivirale wirkstoffe
EP12775659.1A EP2766367B1 (de) 2011-10-14 2012-10-15 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidin-Derivate zur Behandlung von viralen Infekten, insbesondere von Picornavirusinfektionen

Publications (1)

Publication Number Publication Date
SI2766367T1 true SI2766367T1 (sl) 2022-10-28

Family

ID=47071252

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201232005T SI2766367T1 (sl) 2011-10-14 2012-10-15 4-amino-3-fenilamino-6-fenilpirazol(3,4-D)primidinski derivati za zdravljenje virusnih okužb, zlasti pikornavirusnih okužb

Country Status (22)

Country Link
US (1) US9790225B2 (sl)
EP (1) EP2766367B1 (sl)
JP (1) JP6071012B2 (sl)
KR (1) KR20140095467A (sl)
CN (1) CN103946224A (sl)
AU (1) AU2012322750B2 (sl)
BR (1) BR112014008815B1 (sl)
CA (1) CA2850439C (sl)
DK (1) DK2766367T3 (sl)
ES (1) ES2924828T3 (sl)
HR (1) HRP20220928T1 (sl)
HU (1) HUE059217T2 (sl)
IL (1) IL231934A (sl)
LT (1) LT2766367T (sl)
MX (1) MX2014003987A (sl)
PL (1) PL2766367T3 (sl)
PT (1) PT2766367T (sl)
RU (1) RU2014118953A (sl)
SG (2) SG11201401351PA (sl)
SI (1) SI2766367T1 (sl)
WO (1) WO2013053942A1 (sl)
ZA (1) ZA201402226B (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3064207B1 (en) 2015-03-04 2017-12-20 Scandion Oncology A/S 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments
KR102205570B1 (ko) 2018-09-12 2021-01-20 김홍기 뿌리식물 수경재배용 시트

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2965643A (en) 1960-12-20 Derivatives of pyrazolo
US3551428A (en) 1956-02-10 1970-12-29 Ciba Geigy Corp New 1- (or 2-) substituted 4-mercapto-pyrazolo(3,4-d)pyrimidines
DE3712735A1 (de) 1987-04-15 1988-11-10 Boehringer Mannheim Gmbh Neue pyrazolo(3,4-d)pyrimidine, verfahren zu ihrer herstellung und verwendung als arzneimittel
CA2100863A1 (en) 1991-01-23 1992-07-24 David A. Bullough Adenosine kinase inhibitors
TW370529B (en) 1992-12-17 1999-09-21 Pfizer Pyrazolopyrimidines
US5646152A (en) 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
CZ27399A3 (cs) 1999-01-26 2000-08-16 Ústav Experimentální Botaniky Av Čr Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
DE102006029074A1 (de) * 2006-06-22 2007-12-27 Friedrich-Schiller-Universität Jena 4-Amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidin-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung als antivirale Wirkstoffe

Also Published As

Publication number Publication date
CA2850439C (en) 2020-04-07
EP2766367A1 (de) 2014-08-20
PL2766367T3 (pl) 2022-08-22
IL231934A (en) 2017-03-30
PT2766367T (pt) 2022-08-12
SG11201401351PA (en) 2014-08-28
RU2014118953A (ru) 2015-11-20
WO2013053942A1 (de) 2013-04-18
SG10201602846TA (en) 2016-05-30
EP2766367B1 (de) 2022-05-18
US20140296259A1 (en) 2014-10-02
IL231934A0 (en) 2014-05-28
HUE059217T2 (hu) 2022-10-28
HRP20220928T1 (hr) 2022-10-28
ZA201402226B (en) 2015-05-27
CN103946224A (zh) 2014-07-23
BR112014008815A2 (pt) 2017-04-25
BR112014008815B1 (pt) 2021-01-12
NZ623573A (en) 2016-08-26
KR20140095467A (ko) 2014-08-01
LT2766367T (lt) 2022-08-25
AU2012322750B2 (en) 2016-11-10
US9790225B2 (en) 2017-10-17
MX2014003987A (es) 2014-09-22
JP6071012B2 (ja) 2017-02-01
JP2014528468A (ja) 2014-10-27
ES2924828T3 (es) 2022-10-11
DK2766367T3 (da) 2022-08-01
CA2850439A1 (en) 2013-04-18
AU2012322750A1 (en) 2014-04-24

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