SI2307397T1 - 6-substituirani derivati fenoksikroman karboksilne kisline - Google Patents

6-substituirani derivati fenoksikroman karboksilne kisline

Info

Publication number: SI2307397T1
Authority: SI; Slovenia
Prior art keywords: carboxylic acid; acid derivatives; substituted; phenoxychroman carboxylic; substituted phenoxychroman
Prior art date: 2008-06-25

Application number

SI200931031T

Other languages

English (en)

Inventor

Laurence E. Burgess

Christopher T. Clark

Adam Cook

Christopher P. Corrette

Robert Kirk Delisle

George A. Doherty

Kevin W. Hunt

Todd Romoff

Ganghyeok Kim

Original Assignee

Array Biopharma, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-25

Filing date

2009-06-24

Publication date

2014-11-28

2009-06-24 Application filed by Array Biopharma, Inc. filed Critical Array Biopharma, Inc.

2014-11-28 Publication of SI2307397T1 publication Critical patent/SI2307397T1/sl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Otolaryngology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrane Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)

SI200931031T 2008-06-25 2009-06-24 6-substituirani derivati fenoksikroman karboksilne kisline SI2307397T1 (sl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US7561508P	2008-06-25	2008-06-25
PCT/US2009/048499 WO2009158426A1 (en)	2008-06-25	2009-06-24	6-substituted phenoxychroman carboxylic acid derivatives
EP09770959.6A EP2307397B1 (en)	2008-06-25	2009-06-24	6-substituted phenoxychroman carboxylic acid derivatives

Publications (1)

Publication Number	Publication Date
SI2307397T1 true SI2307397T1 (sl)	2014-11-28

Family

ID=40996727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI200931031T SI2307397T1 (sl)	2008-06-25	2009-06-24	6-substituirani derivati fenoksikroman karboksilne kisline

Country Status (32)

Country	Link
US (4)	US8569522B2 (sl)
EP (3)	EP3144303B1 (sl)
JP (2)	JP5753780B2 (sl)
KR (1)	KR101728175B1 (sl)
CN (2)	CN103450138B (sl)
AR (1)	AR072301A1 (sl)
AU (1)	AU2009262274B2 (sl)
BR (1)	BRPI0915513B8 (sl)
CA (1)	CA2729217C (sl)
CL (1)	CL2010001528A1 (sl)
CO (1)	CO6362002A2 (sl)
CR (1)	CR20110037A (sl)
CY (1)	CY1115650T1 (sl)
DK (1)	DK2307397T3 (sl)
ES (2)	ES2582161T3 (sl)
HR (1)	HRP20140988T1 (sl)
IL (2)	IL210198A (sl)
MX (1)	MX2011000173A (sl)
MY (2)	MY185134A (sl)
NZ (1)	NZ590437A (sl)
PH (1)	PH12014500079B1 (sl)
PL (1)	PL2307397T3 (sl)
PT (1)	PT2307397E (sl)
RS (1)	RS53665B1 (sl)
RU (1)	RU2507200C2 (sl)
SG (2)	SG2014013528A (sl)
SI (1)	SI2307397T1 (sl)
TW (2)	TWI436990B (sl)
UA (1)	UA104867C2 (sl)
UY (1)	UY31938A (sl)
WO (1)	WO2009158426A1 (sl)
ZA (1)	ZA201100604B (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP20140988T1 (hr)	2008-06-25	2014-12-05	Array Biopharma, Inc.	Derivati 6-supstituirane fenoksikromankarboksilne kiseline
CN102325767B (zh) *	2008-12-22	2014-05-14	阵列生物制药公司	7-苯氧基色满羧酸衍生物
EP2457900A1 (en)	2010-11-25	2012-05-30	Almirall, S.A.	New pyrazole derivatives having CRTh2 antagonistic behaviour
TWI654180B (zh)	2012-06-29	2019-03-21	美商艾佛艾姆希公司	殺真菌之雜環羧醯胺
TW201507722A (zh) *	2013-04-30	2015-03-01	Bayer Cropscience Ag	做為殺線蟲劑及殺體內寄生蟲劑的ｎ－（２－鹵素－２－苯乙基）－羧醯胺類
WO2015126750A1 (en)	2014-02-19	2015-08-27	Array Biopharma Inc.	BIOMARKERS PREDICTIVE OF RESPONSIVENESS TO TREATMENT WITH A CRTh2 INHIBITOR
CN111057003A (zh) *	2019-12-06	2020-04-24	广安凯特制药有限公司	一种立他司特中间体5,7-二氯-1,2,3,4-四氢异喹啉的合成方法
SE2151519A1 (en) *	2021-12-10	2023-06-11	Amidea Sweden Ab	2-(2,5-dimethoxyphenyl)ethanamine and uses thereof
CN114181039A (zh) *	2021-12-23	2022-03-15	凯美克(上海)医药科技有限公司	一种4,4-二苯基-3-丁烯-1-醇的合成方法
TW202515529A (zh) *	2023-08-29	2025-04-16	韓商Ｊｗ製藥公司	用於治療異位性皮膚炎之雜環衍生物

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US5059609A (en)	1987-10-19	1991-10-22	Pfizer Inc.	Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases
US5006550A (en) *	1989-12-29	1991-04-09	Allergan, Inc.	Chroman esters of phenols and benzoic acids having retinoid-like activity
US5952326A (en)	1997-12-10	1999-09-14	Pfizer Inc.	Tetralin and chroman derivatives useful in the treatment of asthma, arthritis and related diseases
DE19850131A1 (de) *	1998-10-30	2000-05-04	Merck Patent Gmbh	Chromenon- und Chromanonderivate
HK1046280B (zh)	1999-05-21	2004-10-21	辉瑞产品公司	1-三氟甲基-4-羟基-7-哌啶基-氨甲基苯并二氢吡喃衍生物
CA2422342C (en) *	2000-09-14	2009-12-08	Mitsubishi Pharma Corporation	Novel amide derivatives and medicinal use thereof
WO2003029239A1 (en) *	2001-10-04	2003-04-10	Wyeth	Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands
EP1585511B1 (en) *	2002-12-20	2013-01-23	Amgen Inc.	Asthma and allergic inflammation modulators
AU2005328327A1 (en) *	2005-02-25	2006-09-08	Galileo Pharmaceuticals, Inc.	Novel lipoxygenase inhibitors
GB0611781D0 (en) *	2006-06-14	2006-07-26	Argenta Discovery Ltd	2-Oxo-2H-Chromene Compounds
NZ575507A (en)	2006-08-21	2011-10-28	Array Biopharma Inc	4-substituted phenoxyphenylacetic acid derivatives
WO2008054675A2 (en) *	2006-10-31	2008-05-08	Merck & Co., Inc.	Antidiabetic bicyclic compounds
US7960567B2 (en) *	2007-05-02	2011-06-14	Amgen Inc.	Compounds and methods useful for treating asthma and allergic inflammation
US8362056B2 (en)	2007-11-05	2013-01-29	Array Biopharma Inc.	4-heteroaryl-substituted phenoxyphenylacetic acid derivatives
HRP20140988T1 (hr)	2008-06-25	2014-12-05	Array Biopharma, Inc.	Derivati 6-supstituirane fenoksikromankarboksilne kiseline
CN102325767B (zh) *	2008-12-22	2014-05-14	阵列生物制药公司	7-苯氧基色满羧酸衍生物

2009
- 2009-06-24 HR HRP20140988AT patent/HRP20140988T1/hr unknown
- 2009-06-24 KR KR1020117001795A patent/KR101728175B1/ko not_active Expired - Fee Related
- 2009-06-24 SG SG2014013528A patent/SG2014013528A/en unknown
- 2009-06-24 BR BRPI0915513A patent/BRPI0915513B8/pt not_active IP Right Cessation
- 2009-06-24 MY MYPI2014001094A patent/MY185134A/en unknown
- 2009-06-24 MY MYPI2010006174A patent/MY161425A/en unknown
- 2009-06-24 MX MX2011000173A patent/MX2011000173A/es active IP Right Grant
- 2009-06-24 JP JP2011516614A patent/JP5753780B2/ja not_active Expired - Fee Related
- 2009-06-24 ES ES13195749.0T patent/ES2582161T3/es active Active
- 2009-06-24 ES ES09770959.6T patent/ES2524314T3/es active Active
- 2009-06-24 RU RU2011102595/04A patent/RU2507200C2/ru active
- 2009-06-24 NZ NZ590437A patent/NZ590437A/en not_active IP Right Cessation
- 2009-06-24 EP EP16170994.4A patent/EP3144303B1/en active Active
- 2009-06-24 AR ARP090102331A patent/AR072301A1/es active IP Right Grant
- 2009-06-24 SI SI200931031T patent/SI2307397T1/sl unknown
- 2009-06-24 EP EP13195749.0A patent/EP2826774B1/en active Active
- 2009-06-24 EP EP09770959.6A patent/EP2307397B1/en active Active
- 2009-06-24 DK DK09770959.6T patent/DK2307397T3/da active
- 2009-06-24 CN CN201310354758.0A patent/CN103450138B/zh not_active Expired - Fee Related
- 2009-06-24 WO PCT/US2009/048499 patent/WO2009158426A1/en not_active Ceased
- 2009-06-24 RS RS20140627A patent/RS53665B1/sr unknown
- 2009-06-24 PT PT97709596T patent/PT2307397E/pt unknown
- 2009-06-24 CA CA2729217A patent/CA2729217C/en not_active Expired - Fee Related
- 2009-06-24 US US13/001,201 patent/US8569522B2/en not_active Expired - Fee Related
- 2009-06-24 UA UAA201100801A patent/UA104867C2/uk unknown
- 2009-06-24 SG SG2014013544A patent/SG2014013544A/en unknown
- 2009-06-24 UY UY0001031938A patent/UY31938A/es not_active Application Discontinuation
- 2009-06-24 PL PL09770959T patent/PL2307397T3/pl unknown
- 2009-06-24 CN CN2009801332711A patent/CN102131794B/zh not_active Expired - Fee Related
- 2009-06-24 AU AU2009262274A patent/AU2009262274B2/en not_active Ceased
- 2009-06-25 TW TW098121432A patent/TWI436990B/zh not_active IP Right Cessation
- 2009-06-25 TW TW103112407A patent/TWI476186B/zh not_active IP Right Cessation
2010
- 2010-12-23 CL CL2010001528A patent/CL2010001528A1/es unknown
- 2010-12-23 IL IL210198A patent/IL210198A/en active IP Right Grant
2011
- 2011-01-21 CR CR20110037A patent/CR20110037A/es unknown
- 2011-01-24 ZA ZA2011/00604A patent/ZA201100604B/en unknown
- 2011-01-28 CO CO11010027A patent/CO6362002A2/es active IP Right Grant
2013
- 2013-08-29 US US14/013,898 patent/US8716498B2/en not_active Expired - Fee Related
2014
- 2014-01-08 PH PH12014500079A patent/PH12014500079B1/en unknown
- 2014-03-27 JP JP2014065161A patent/JP2014122241A/ja not_active Withdrawn
- 2014-03-31 US US14/231,356 patent/US9096567B2/en not_active Expired - Fee Related
- 2014-10-21 CY CY20141100859T patent/CY1115650T1/el unknown
2015
- 2015-05-04 US US14/702,947 patent/US9556139B2/en not_active Expired - Fee Related
- 2015-09-21 IL IL241754A patent/IL241754A/en active IP Right Grant

Also Published As

Publication number	Publication date
EP3144303A1 (en)	2017-03-22
WO2009158426A1 (en)	2009-12-30
US8569522B2 (en)	2013-10-29
US9556139B2 (en)	2017-01-31
HK1155735A1 (en)	2012-05-25
JP2011526290A (ja)	2011-10-06
US9096567B2 (en)	2015-08-04
CR20110037A (es)	2011-03-14
US20150232442A1 (en)	2015-08-20
CA2729217C (en)	2016-09-06
CL2010001528A1 (es)	2011-07-01
IL210198A (en)	2015-10-29
CN103450138A (zh)	2013-12-18
AR072301A1 (es)	2010-08-18
EP3144303B1 (en)	2018-09-26
TWI476186B (zh)	2015-03-11
US20140221342A1 (en)	2014-08-07
EP2826774A1 (en)	2015-01-21
BRPI0915513B8 (pt)	2021-05-25
ES2582161T3 (es)	2016-09-09
BRPI0915513B1 (pt)	2019-11-19
TW201427965A (zh)	2014-07-16
US20140005418A1 (en)	2014-01-02
ZA201100604B (en)	2015-08-26
RU2507200C2 (ru)	2014-02-20
EP2307397B1 (en)	2014-08-20
AU2009262274B2 (en)	2013-08-01
SG2014013528A (en)	2014-07-30
UY31938A (es)	2011-01-31
ES2524314T3 (es)	2014-12-05
KR20110027798A (ko)	2011-03-16
PT2307397E (pt)	2014-10-29
SG2014013544A (en)	2014-07-30
MY185134A (en)	2021-04-30
UA104867C2 (uk)	2014-03-25
MY161425A (en)	2017-04-14
JP2014122241A (ja)	2014-07-03
KR101728175B1 (ko)	2017-04-18
CY1115650T1 (el)	2017-01-04
IL241754A0 (en)	2015-11-30
CA2729217A1 (en)	2009-12-30
CN103450138B (zh)	2015-04-08
EP2307397A1 (en)	2011-04-13
CN102131794A (zh)	2011-07-20
PL2307397T3 (pl)	2015-02-27
IL241754A (en)	2017-02-28
BRPI0915513A2 (pt)	2016-01-26
PH12014500079A1 (en)	2015-02-09
TWI436990B (zh)	2014-05-11
US20110105463A1 (en)	2011-05-05
RU2011102595A (ru)	2012-07-27
JP5753780B2 (ja)	2015-07-22
RS53665B1 (sr)	2015-04-30
US8716498B2 (en)	2014-05-06
EP2826774B1 (en)	2016-05-25
DK2307397T3 (da)	2014-11-03
HRP20140988T1 (hr)	2014-12-05
CN102131794B (zh)	2013-09-25
IL210198A0 (en)	2011-03-31
MX2011000173A (es)	2011-06-20
AU2009262274A1 (en)	2009-12-30
NZ590437A (en)	2012-07-27
TW201022222A (en)	2010-06-16
CO6362002A2 (es)	2012-01-20
PH12014500079B1 (en)	2015-02-09

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