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SI1703965T1 - Naprava, postopek in uporaba za izdelavo majhnih delcev - Google Patents

Naprava, postopek in uporaba za izdelavo majhnih delcev

Info

Publication number
SI1703965T1
SI1703965T1 SI200432087T SI200432087T SI1703965T1 SI 1703965 T1 SI1703965 T1 SI 1703965T1 SI 200432087 T SI200432087 T SI 200432087T SI 200432087 T SI200432087 T SI 200432087T SI 1703965 T1 SI1703965 T1 SI 1703965T1
Authority
SI
Slovenia
Prior art keywords
formation
small particles
particles
small
Prior art date
Application number
SI200432087T
Other languages
English (en)
Inventor
Mustafa Demirbuker
Original Assignee
Xspray Microparticles Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xspray Microparticles Ab filed Critical Xspray Microparticles Ab
Publication of SI1703965T1 publication Critical patent/SI1703965T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/44—Mixers in which the components are pressed through slits
    • B01F25/441—Mixers in which the components are pressed through slits characterised by the configuration of the surfaces forming the slits
    • B01F25/4412—Mixers in which the components are pressed through slits characterised by the configuration of the surfaces forming the slits the slits being formed between opposed planar surfaces, e.g. pushed again each other by springs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/44—Mixers in which the components are pressed through slits
    • B01F25/442—Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation
    • B01F25/4422—Mixers in which the components are pressed through slits characterised by the relative position of the surfaces during operation the surfaces being maintained in a fixed but adjustable position, spaced from each other, therefore allowing the slit spacing to be varied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nozzles (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
SI200432087T 2003-12-22 2004-12-20 Naprava, postopek in uporaba za izdelavo majhnih delcev SI1703965T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0303476A SE0303476D0 (sv) 2003-12-22 2003-12-22 Device, method and use for the formation of small particles
PCT/SE2004/001936 WO2005061090A1 (en) 2003-12-22 2004-12-20 Device, method and use for the formation of small particles
EP04809109.4A EP1703965B1 (en) 2003-12-22 2004-12-20 Device, method and use for the formation of small particles

Publications (1)

Publication Number Publication Date
SI1703965T1 true SI1703965T1 (sl) 2013-11-29

Family

ID=30768795

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200432087T SI1703965T1 (sl) 2003-12-22 2004-12-20 Naprava, postopek in uporaba za izdelavo majhnih delcev

Country Status (12)

Country Link
US (2) US7798475B2 (sl)
EP (1) EP1703965B1 (sl)
JP (1) JP5032848B2 (sl)
CN (1) CN100528316C (sl)
AU (1) AU2004305413B2 (sl)
CA (1) CA2550806C (sl)
DK (1) DK1703965T3 (sl)
ES (1) ES2429064T3 (sl)
PL (1) PL1703965T3 (sl)
SE (1) SE0303476D0 (sl)
SI (1) SI1703965T1 (sl)
WO (1) WO2005061090A1 (sl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0303476D0 (sv) * 2003-12-22 2003-12-22 Censdelivery Ab Device, method and use for the formation of small particles
JP2011507676A (ja) * 2007-12-07 2011-03-10 エクスプレイ ミクロパーティクルズ アクティエボラーグ 粒子を生成する方法と構造
CN103037961A (zh) * 2010-06-14 2013-04-10 X喷雾微粒公司 用于生产微粒的装置与方法
AU2011305567A1 (en) * 2010-09-22 2013-05-02 Map Pharmaceuticals, Inc. Corticosteroid particles and method of production
AU2013208324B2 (en) 2012-01-13 2017-11-23 Xspray Microparticles Ab A pharmaceutical composition comprising stable, amorphous hybrid nanoparticles of at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component
EP2705838A1 (en) 2012-09-06 2014-03-12 Xspray Microparticles Ab Tiotropium preparations
WO2015053857A2 (en) * 2013-10-10 2015-04-16 New York University Efficient collection of nanoparticles
US10206873B1 (en) 2017-08-04 2019-02-19 Colorado Can Llc Dry powder formation using a variably constrained, divided pathway for mixing fluid streams
CN113292537B (zh) 2018-06-15 2024-04-05 汉达癌症医药责任有限公司 激酶抑制剂的盐类及其组合物
CN110605036B (zh) * 2019-08-30 2022-05-10 扬州大学 一种可非等动量受限射流撞击混合的方法
WO2021255645A1 (en) * 2020-06-18 2021-12-23 Capsugel Belgium Nv Method for making multiparticulates from a liquid feed employing a spinning disc sprayer
EP4190437A1 (en) 2021-12-03 2023-06-07 SiTec PharmaBio SL Process and apparatus for the manufacture of solid microparticles
EP4598504A2 (en) 2022-10-05 2025-08-13 Mireca Medicines GmbH Microparticle and implant formulations for cgmp analog therapy
AU2024215796A1 (en) 2023-01-31 2025-05-15 Handa Oncology, Llc Improved cabozantinib compositions and methods of use

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5117145B2 (sl) * 1971-09-10 1976-05-31
FI51602C (fi) * 1973-12-19 1977-02-10 Outokumpu Oy Tapa ja laite sulan aineen hajottamiseksi kaasumaisen tai höyrymäisen aineen suihkulla.
US4206160A (en) * 1978-09-25 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Mechanical device to produce a finely dispersed aerosol
US4284590A (en) * 1980-09-17 1981-08-18 Respiratory Care, Inc. Multiple aspirator for nebulizer
US5232164A (en) * 1990-05-09 1993-08-03 Resch D R Precisely adjustable atomizer
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
CA2112093C (en) * 1993-12-21 1995-02-21 John A. Burgener Parallel path induction nebulizer
US5609798A (en) * 1995-06-07 1997-03-11 Msp Corporation High output PSL aerosol generator
SE504449C2 (sv) * 1995-06-22 1997-02-17 Libradon Ab Anordning för blandning av luft och vatten i en vattenrenare
US6086052A (en) * 1996-12-03 2000-07-11 Rowe; Carroll G. Foam generating apparatus
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
US6076748A (en) * 1998-05-04 2000-06-20 Resch; Darrel R. Odor control atomizer utilizing ozone and water
GB9915975D0 (en) * 1999-07-07 1999-09-08 Bradford Particle Design Ltd Method for the formation of particles
CN2406721Y (zh) * 2000-01-22 2000-11-22 邹龙贵 制粒包衣机
TW586963B (en) * 2001-07-20 2004-05-11 Nektar Therapeutics Uk Ltd Method and apparatus for preparing target substance in particulate form and fluid inlet assembly for said apparatus
SE0303476D0 (sv) * 2003-12-22 2003-12-22 Censdelivery Ab Device, method and use for the formation of small particles
DK1697056T3 (da) * 2003-12-22 2012-01-02 Gea Process Engineering As Dyse til forstøvning af en væske ved hjælp af en gas og fremgangsmåde til forstøvning

Also Published As

Publication number Publication date
WO2005061090A1 (en) 2005-07-07
EP1703965B1 (en) 2013-07-03
CN1917939A (zh) 2007-02-21
SE0303476D0 (sv) 2003-12-22
CN100528316C (zh) 2009-08-19
US20070116650A1 (en) 2007-05-24
JP2007515290A (ja) 2007-06-14
EP1703965A1 (en) 2006-09-27
AU2004305413B2 (en) 2010-11-18
US20110049737A1 (en) 2011-03-03
US8167279B2 (en) 2012-05-01
AU2004305413A1 (en) 2005-07-07
PL1703965T3 (pl) 2013-12-31
CA2550806A1 (en) 2005-07-07
ES2429064T3 (es) 2013-11-12
CA2550806C (en) 2012-08-28
US7798475B2 (en) 2010-09-21
DK1703965T3 (da) 2013-09-30
JP5032848B2 (ja) 2012-09-26

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