[go: up one dir, main page]

SI1781631T1 - Derivati diarilmetil piperazina njihovi pripravki in uporaba - Google Patents

Derivati diarilmetil piperazina njihovi pripravki in uporaba

Info

Publication number
SI1781631T1
SI1781631T1 SI200531515T SI200531515T SI1781631T1 SI 1781631 T1 SI1781631 T1 SI 1781631T1 SI 200531515 T SI200531515 T SI 200531515T SI 200531515 T SI200531515 T SI 200531515T SI 1781631 T1 SI1781631 T1 SI 1781631T1
Authority
SI
Slovenia
Prior art keywords
preparations
piperazine derivatives
diarylmethyl piperazine
diarylmethyl
derivatives
Prior art date
Application number
SI200531515T
Other languages
English (en)
Inventor
William Brown
Andrew Griffin
Thomas Hudzik
Carla Maciag
Gennady Smagin
Christopher Walpole
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32906880&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1781631(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SI1781631T1 publication Critical patent/SI1781631T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI200531515T 2004-08-02 2005-07-27 Derivati diarilmetil piperazina njihovi pripravki in uporaba SI1781631T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0401968A SE0401968D0 (sv) 2004-08-02 2004-08-02 Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
US60236304P 2004-08-18 2004-08-18
EP05762524A EP1781631B1 (en) 2004-08-02 2005-07-27 Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
PCT/SE2005/001186 WO2006014133A1 (en) 2004-08-02 2005-07-27 Diarylmethyl piperazine derivatives, preparations thereof and uses thereof

Publications (1)

Publication Number Publication Date
SI1781631T1 true SI1781631T1 (sl) 2012-05-31

Family

ID=32906880

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200531515T SI1781631T1 (sl) 2004-08-02 2005-07-27 Derivati diarilmetil piperazina njihovi pripravki in uporaba

Country Status (22)

Country Link
US (2) US20070249619A1 (sl)
EP (1) EP1781631B1 (sl)
JP (1) JP5006785B2 (sl)
CN (1) CN1993338B (sl)
AR (1) AR050260A1 (sl)
AT (1) ATE542806T1 (sl)
AU (1) AU2005267929B2 (sl)
BR (1) BRPI0514014A (sl)
CA (1) CA2576067C (sl)
ES (1) ES2379364T3 (sl)
NZ (1) NZ553539A (sl)
PL (1) PL1781631T3 (sl)
PT (1) PT1781631E (sl)
RS (1) RS52315B (sl)
RU (1) RU2404172C2 (sl)
SE (1) SE0401968D0 (sl)
SG (1) SG155181A1 (sl)
SI (1) SI1781631T1 (sl)
TW (1) TWI370124B (sl)
UA (1) UA87146C2 (sl)
WO (1) WO2006014133A1 (sl)
ZA (1) ZA200700680B (sl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7229994B2 (en) 2001-05-18 2007-06-12 Astrazeneca Ab 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
HRP20120343T1 (hr) * 2004-08-02 2012-05-31 Astrazeneca Ab Derivati diarilmetil piperazina, njihovi pripravci i njihova uporaba
SE0401968D0 (sv) * 2004-08-02 2004-08-02 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
AU2008334705B2 (en) 2007-12-11 2011-06-16 F. Hoffmann-La Roche Ag Inhibitors of stearoyl-CoA desaturase
WO2009142587A1 (en) * 2008-05-20 2009-11-26 Astrazeneca Ab Method of treating anxious major depressive disorder
US8314250B2 (en) 2009-11-24 2012-11-20 Hoffmann-La Roche Inc. Sultam derivatives
US20110207745A1 (en) * 2009-11-25 2011-08-25 Astrazeneca Ab Solid forms of 4--n,n-diethylbenzamide, compositions thereof, and uses therewith
US9073881B2 (en) 2011-09-23 2015-07-07 Hoffmann-La Roche Inc. Benzoic acid derivatives

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH583713A5 (sl) * 1973-06-29 1977-01-14 Cermol Sa
US4568649A (en) * 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
SE8500573D0 (sv) * 1985-02-08 1985-02-08 Ferrosan Ab Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
US5840896A (en) * 1989-11-22 1998-11-24 Janssen Pharmaceutica, N.V. Method of preventing or limiting reperfusion damage
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
US5807858A (en) * 1996-06-05 1998-09-15 Delta Pharmaceutical, Inc. Compositions and methods for reducing respiratory depression
US5681830A (en) * 1992-02-03 1997-10-28 Delta Pharmaceuticals, Inc. Opioid compounds
US5574159A (en) * 1992-02-03 1996-11-12 Delta Pharmaceuticals, Inc. Opioid compounds and methods for making therefor
WO1995004051A1 (en) * 1993-07-30 1995-02-09 The Wellcome Foundation Limited Piperazine compounds used in therapy
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9904674D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
SE0101766D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
US7229994B2 (en) * 2001-05-18 2007-06-12 Astrazeneca Ab 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders
CA2464471C (en) * 2001-10-29 2012-05-15 Ardent Pharmaceuticals, Inc. Method of treating depression with delta receptor agonist compounds
US8476280B2 (en) * 2002-05-09 2013-07-02 Versi Group, Llc Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
SE0203303D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203300D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) * 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0400027D0 (sv) * 2004-01-09 2004-01-09 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
SE0401968D0 (sv) * 2004-08-02 2004-08-02 Astrazeneca Ab Diarylmethyl piperazine derivatives, preparations thereof and uses thereof

Also Published As

Publication number Publication date
BRPI0514014A (pt) 2008-05-27
ES2379364T3 (es) 2012-04-25
PT1781631E (pt) 2012-05-07
AU2005267929B2 (en) 2010-04-08
ZA200700680B (en) 2008-09-25
EP1781631A1 (en) 2007-05-09
WO2006014133A1 (en) 2006-02-09
RS52315B (sr) 2012-12-31
CN1993338B (zh) 2011-07-06
AU2005267929A1 (en) 2006-02-09
SG155181A1 (en) 2009-09-30
NZ553539A (en) 2010-09-30
CN1993338A (zh) 2007-07-04
SE0401968D0 (sv) 2004-08-02
JP2008508350A (ja) 2008-03-21
UA87146C2 (ru) 2009-06-25
JP5006785B2 (ja) 2012-08-22
RU2404172C2 (ru) 2010-11-20
ATE542806T1 (de) 2012-02-15
RU2007101522A (ru) 2008-09-10
US20070249619A1 (en) 2007-10-25
AR050260A1 (es) 2006-10-11
US20060030569A1 (en) 2006-02-09
PL1781631T3 (pl) 2012-07-31
TWI370124B (en) 2012-08-11
TW200612930A (en) 2006-05-01
CA2576067C (en) 2011-05-03
EP1781631B1 (en) 2012-01-25
CA2576067A1 (en) 2006-02-09

Similar Documents

Publication Publication Date Title
ZA200700680B (en) Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
ZA200706254B (en) 18-methyl-19-nor-17-pregn-4-en-21,17-carbolactones and pharmaceutical preparations comprising the same
IL209494A (en) Formulations of insulin oligomeric monoconogues and their use
IL180682A0 (en) N-hydroxamide derivatives, their preparation and use
EP1828223A4 (en) Novel betulin derivatives, their preparation and their use
IL175817A0 (en) Benzoxazine derivatives and uses thereof
IL169366A0 (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
IL176513A0 (en) Diarylmethyl piperazine derivatives, preparations thereof and used thereof
IL169360A0 (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
AU2003300262A1 (en) Phthalimidylazo dyes, processes for the preparation thereof and the use thereof
IL180544A0 (en) Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
AU2003299336A1 (en) Diphosphines, preparation and uses thereof
HK1096679A (en) Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
IL176517A0 (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
IL176509A0 (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
HK1105783A (en) Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
ZA200704806B (en) Novel betulin derivatives, preparation thereof and use thereof
HK1096678A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
HK1096677A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
HK1085477A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
HK1081547A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
HK1085476A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
HK1085474A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
HK1081433A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
HK1086834A (en) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof