SI1765337T1 - Kombinacija tenofovirja, ritonavirja in TMC114 - Google Patents
Kombinacija tenofovirja, ritonavirja in TMC114Info
- Publication number
- SI1765337T1 SI1765337T1 SI200530488T SI200530488T SI1765337T1 SI 1765337 T1 SI1765337 T1 SI 1765337T1 SI 200530488 T SI200530488 T SI 200530488T SI 200530488 T SI200530488 T SI 200530488T SI 1765337 T1 SI1765337 T1 SI 1765337T1
- Authority
- SI
- Slovenia
- Prior art keywords
- tenofovir
- ritonavir
- combination
- tmc114
- hiv
- Prior art date
Links
- NCDNCNXCDXHOMX-UHFFFAOYSA-N Ritonavir Natural products C=1C=CC=CC=1CC(NC(=O)OCC=1SC=NC=1)C(O)CC(CC=1C=CC=CC=1)NC(=O)C(C(C)C)NC(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-UHFFFAOYSA-N 0.000 title abstract 2
- 229960005107 darunavir Drugs 0.000 title abstract 2
- CJBJHOAVZSMMDJ-HEXNFIEUSA-N darunavir Chemical compound C([C@@H]([C@H](O)CN(CC(C)C)S(=O)(=O)C=1C=CC(N)=CC=1)NC(=O)O[C@@H]1[C@@H]2CCO[C@@H]2OC1)C1=CC=CC=C1 CJBJHOAVZSMMDJ-HEXNFIEUSA-N 0.000 title abstract 2
- 229960000311 ritonavir Drugs 0.000 title abstract 2
- NCDNCNXCDXHOMX-XGKFQTDJSA-N ritonavir Chemical compound N([C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC=1C=CC=CC=1)NC(=O)OCC=1SC=NC=1)CC=1C=CC=CC=1)C(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-XGKFQTDJSA-N 0.000 title abstract 2
- 229960004556 tenofovir Drugs 0.000 title abstract 2
- VCMJCVGFSROFHV-WZGZYPNHSA-N tenofovir disoproxil fumarate Chemical compound OC(=O)\C=C\C(O)=O.N1=CN=C2N(C[C@@H](C)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C)C=NC2=C1N VCMJCVGFSROFHV-WZGZYPNHSA-N 0.000 title abstract 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical class OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 230000036436 anti-hiv Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Aiming, Guidance, Guns With A Light Source, Armor, Camouflage, And Targets (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04103256 | 2004-07-08 | ||
| EP05774136A EP1765337B1 (en) | 2004-07-08 | 2005-07-08 | Combination of tenofovir, ritonavir and tmc114 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1765337T1 true SI1765337T1 (sl) | 2009-02-28 |
Family
ID=34929311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200530488T SI1765337T1 (sl) | 2004-07-08 | 2005-07-08 | Kombinacija tenofovirja, ritonavirja in TMC114 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20070208009A1 (sl) |
| EP (1) | EP1765337B1 (sl) |
| JP (1) | JP2008505870A (sl) |
| CN (1) | CN1984654A (sl) |
| AT (1) | ATE406161T1 (sl) |
| AU (1) | AU2005261701A1 (sl) |
| BR (1) | BRPI0513051A (sl) |
| CA (1) | CA2572551A1 (sl) |
| DE (1) | DE602005009366D1 (sl) |
| DK (1) | DK1765337T3 (sl) |
| ES (1) | ES2313394T3 (sl) |
| HR (1) | HRP20080612T3 (sl) |
| MX (1) | MXPA06014930A (sl) |
| NZ (1) | NZ551841A (sl) |
| PL (1) | PL1765337T3 (sl) |
| RU (1) | RU2368380C2 (sl) |
| SI (1) | SI1765337T1 (sl) |
| WO (1) | WO2006005720A1 (sl) |
| ZA (1) | ZA200700176B (sl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1814547A1 (en) * | 2004-11-16 | 2007-08-08 | Boehringer Ingelheim International Gmbh | Method for treating hiv infection through co-administration of tipranavir and darunavir |
| MX2010004734A (es) * | 2007-10-29 | 2010-05-20 | Cipla Ltd | Nueva combinacion anti-retrovirica. |
| GT200800303A (es) * | 2007-12-24 | 2009-09-18 | Combinacion anti-retroviral | |
| CN102876714A (zh) * | 2011-09-07 | 2013-01-16 | 深圳市易瑞生物技术有限公司 | 用慢病毒检测hiv耐药表型 |
| WO2013057469A1 (en) * | 2011-10-20 | 2013-04-25 | Cipla Limited | Pharmaceutical antiretroviral compositions |
| CA2885763C (en) * | 2012-10-23 | 2021-04-06 | Cipla Limited | Pharmaceutical antiretroviral composition |
| WO2014184553A1 (en) * | 2013-05-15 | 2014-11-20 | Cipla Limited | Pharmaceutical antiretroviral compositions |
| EP3038607A2 (en) * | 2013-08-29 | 2016-07-06 | Teva Pharmaceutical Industries Ltd. | Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir and a monolithic tablet comprising darunavir and ritonavir |
| TW201622731A (zh) * | 2014-04-08 | 2016-07-01 | 泰瓦藥品工業有限公司 | 包含恩曲他濱（Ｅｍｔｒｉｃｉｔａｂｉｎｅ）、替諾福韋（Ｔｅｎｏｆｏｖｉｒ）、地瑞那韋（Ｄａｒｕｎａｖｉｒ）及利托那韋（Ｒｉｔｏｎａｖｉｒ）之單位劑型以及包含地瑞那韋及利托那韋之單層錠劑 |
| GB201509431D0 (en) * | 2015-06-01 | 2015-07-15 | Equigerminal Sa | Antiviral composition |
| US10213507B2 (en) * | 2017-03-10 | 2019-02-26 | The Florida International University Board Of Trustees | Compositions and methods for treating HIV-associated neurocognitive disorders |
| RU2662160C9 (ru) * | 2017-07-03 | 2018-10-22 | Александрович Иващенко Андрей | Комбинированный лекарственный препарат для терапии вирусных инфекций |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI286476B (en) * | 2001-12-12 | 2007-09-11 | Tibotec Pharm Ltd | Combination of cytochrome P450 dependent protease inhibitors |
-
2005
- 2005-07-08 EP EP05774136A patent/EP1765337B1/en not_active Expired - Lifetime
- 2005-07-08 CN CNA2005800230750A patent/CN1984654A/zh active Pending
- 2005-07-08 JP JP2007519807A patent/JP2008505870A/ja not_active Withdrawn
- 2005-07-08 MX MXPA06014930A patent/MXPA06014930A/es active IP Right Grant
- 2005-07-08 NZ NZ551841A patent/NZ551841A/en not_active IP Right Cessation
- 2005-07-08 DK DK05774136T patent/DK1765337T3/da active
- 2005-07-08 AT AT05774136T patent/ATE406161T1/de not_active IP Right Cessation
- 2005-07-08 CA CA002572551A patent/CA2572551A1/en not_active Abandoned
- 2005-07-08 PL PL05774136T patent/PL1765337T3/pl unknown
- 2005-07-08 RU RU2007104774/15A patent/RU2368380C2/ru not_active IP Right Cessation
- 2005-07-08 HR HR20080612T patent/HRP20080612T3/xx unknown
- 2005-07-08 ES ES05774136T patent/ES2313394T3/es not_active Expired - Lifetime
- 2005-07-08 BR BRPI0513051-4A patent/BRPI0513051A/pt not_active IP Right Cessation
- 2005-07-08 US US11/571,599 patent/US20070208009A1/en not_active Abandoned
- 2005-07-08 DE DE602005009366T patent/DE602005009366D1/de not_active Expired - Fee Related
- 2005-07-08 AU AU2005261701A patent/AU2005261701A1/en not_active Abandoned
- 2005-07-08 WO PCT/EP2005/053266 patent/WO2006005720A1/en not_active Ceased
- 2005-07-08 SI SI200530488T patent/SI1765337T1/sl unknown
-
2007
- 2007-01-05 ZA ZA200700176A patent/ZA200700176B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2572551A1 (en) | 2006-01-19 |
| BRPI0513051A (pt) | 2008-04-22 |
| RU2007104774A (ru) | 2008-08-20 |
| US20070208009A1 (en) | 2007-09-06 |
| MXPA06014930A (es) | 2007-02-28 |
| EP1765337A1 (en) | 2007-03-28 |
| DE602005009366D1 (de) | 2008-10-09 |
| ZA200700176B (en) | 2008-04-30 |
| CN1984654A (zh) | 2007-06-20 |
| EP1765337B1 (en) | 2008-08-27 |
| ATE406161T1 (de) | 2008-09-15 |
| ES2313394T3 (es) | 2009-03-01 |
| HRP20080612T3 (hr) | 2009-01-31 |
| PL1765337T3 (pl) | 2009-02-27 |
| AU2005261701A1 (en) | 2006-01-19 |
| NZ551841A (en) | 2009-04-30 |
| DK1765337T3 (da) | 2009-01-05 |
| RU2368380C2 (ru) | 2009-09-27 |
| WO2006005720A1 (en) | 2006-01-19 |
| JP2008505870A (ja) | 2008-02-28 |
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