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SI1745064T1 - Spojine za inhibiranje proteasomskega encima - Google Patents

Spojine za inhibiranje proteasomskega encima

Info

Publication number
SI1745064T1
SI1745064T1 SI200531248T SI200531248T SI1745064T1 SI 1745064 T1 SI1745064 T1 SI 1745064T1 SI 200531248 T SI200531248 T SI 200531248T SI 200531248 T SI200531248 T SI 200531248T SI 1745064 T1 SI1745064 T1 SI 1745064T1
Authority
SI
Slovenia
Prior art keywords
compounds
enzyme inhibition
proteasome enzyme
proteasome
inhibition
Prior art date
Application number
SI200531248T
Other languages
English (en)
Inventor
Mark S Smyth
Guy J Laidig
Ronald T Borchardt
Barry A Bunin
Craig M Crews
John H Musser
John Clifford Chabala
Original Assignee
Proteolix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proteolix Inc filed Critical Proteolix Inc
Priority claimed from EP05735686A external-priority patent/EP1745064B1/en
Publication of SI1745064T1 publication Critical patent/SI1745064T1/sl

Links

SI200531248T 2004-04-15 2005-04-14 Spojine za inhibiranje proteasomskega encima SI1745064T1 (sl)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US56234004P 2004-04-15 2004-04-15
US56909604P 2004-05-07 2004-05-07
US59940104P 2004-08-06 2004-08-06
US61015904P 2004-09-14 2004-09-14
US61000204P 2004-09-14 2004-09-14
US61000104P 2004-09-14 2004-09-14
US62057304P 2004-10-20 2004-10-20
EP05735686A EP1745064B1 (en) 2004-04-15 2005-04-14 Compounds for proteasome enzyme inhibition
PCT/US2005/012740 WO2005105827A2 (en) 2004-04-15 2005-04-14 Compounds for proteasome enzyme inhibition

Publications (1)

Publication Number Publication Date
SI1745064T1 true SI1745064T1 (sl) 2011-05-31

Family

ID=38704582

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200531248T SI1745064T1 (sl) 2004-04-15 2005-04-14 Spojine za inhibiranje proteasomskega encima

Country Status (3)

Country Link
CN (1) CN101006098B (sl)
ES (1) ES2358268T3 (sl)
SI (1) SI1745064T1 (sl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010003732A (es) * 2007-10-04 2010-08-09 Onyx Therapeutics Inc Inhibidores de peptido cetona epoxi de proteasa cristalina y la sintesis de ceto-epoxidos de aminoacido.
GB0914883D0 (en) 2009-08-26 2009-09-30 Univ Belfast Compound
CN109096370B (zh) * 2012-07-26 2022-03-18 圣特莱国际公司 多肽环氧酮化合物
CN103641890B (zh) * 2013-12-19 2015-08-19 重庆泰濠制药有限公司 一种卡非佐米的合成方法
CN104844540A (zh) * 2015-05-18 2015-08-19 上海凯欣生物医药科技有限公司 一种(2s)-2-氨基-4-甲基-1-[(2r)-2-甲基环氧乙烷基]-1-戊酮三氟乙酸盐的新晶型及其制备方法
CN105440106A (zh) * 2015-12-17 2016-03-30 昆明贵研药业有限公司 一种卡非佐米的制备方法
CN109689635A (zh) * 2016-09-14 2019-04-26 费森尤斯卡比肿瘤学有限公司 一种用于纯化卡非佐米中间体的方法
CN115808492A (zh) * 2021-09-14 2023-03-17 中国科学院深圳先进技术研究院 一种阿尔兹海默症生物标志物天冬酰胺及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6831099B1 (en) * 1999-05-12 2004-12-14 Yale University Enzyme inhibition
EP1221962A2 (en) * 1999-10-20 2002-07-17 Osteoscreen, Inc. Inhibitors of proteasomal activity for stimulating bone and hair growth

Also Published As

Publication number Publication date
ES2358268T3 (es) 2011-05-09
CN101006098B (zh) 2014-10-29
CN101006098A (zh) 2007-07-25

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