SI1742957T1 - Postopek za pripravo telitromicina - Google Patents
Postopek za pripravo telitromicinaInfo
- Publication number
- SI1742957T1 SI1742957T1 SI200530112T SI200530112T SI1742957T1 SI 1742957 T1 SI1742957 T1 SI 1742957T1 SI 200530112 T SI200530112 T SI 200530112T SI 200530112 T SI200530112 T SI 200530112T SI 1742957 T1 SI1742957 T1 SI 1742957T1
- Authority
- SI
- Slovenia
- Prior art keywords
- formula
- xiia
- benzoyl
- preparation
- deoxy
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- LJVAJPDWBABPEJ-PNUFFHFMSA-N telithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)[C@@H](C)C(=O)O[C@@H]([C@]2(OC(=O)N(CCCCN3C=C(N=C3)C=3C=NC=CC=3)[C@@H]2[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)OC)C)CC)[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O LJVAJPDWBABPEJ-PNUFFHFMSA-N 0.000 title 1
- 229960003250 telithromycin Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 3
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 3
- 125000002962 imidazol-1-yl group Chemical group [*]N1C([H])=NC([H])=C1[H] 0.000 abstract 3
- 229960002626 clarithromycin Drugs 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN491MU2004 | 2004-04-28 | ||
| EP05775551A EP1742957B1 (en) | 2004-04-28 | 2005-04-25 | Process for the preparation of telithromycin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1742957T1 true SI1742957T1 (sl) | 2008-04-30 |
Family
ID=35159987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200530112T SI1742957T1 (sl) | 2004-04-28 | 2005-04-25 | Postopek za pripravo telitromicina |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20070260066A1 (sl) |
| EP (1) | EP1742957B1 (sl) |
| AT (1) | ATE373009T1 (sl) |
| AU (1) | AU2005238313A1 (sl) |
| CA (1) | CA2559281A1 (sl) |
| DE (1) | DE602005002475T2 (sl) |
| ES (1) | ES2294733T3 (sl) |
| PL (1) | PL1742957T3 (sl) |
| SI (1) | SI1742957T1 (sl) |
| WO (1) | WO2005105821A2 (sl) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1638549A4 (en) | 2003-03-10 | 2011-06-15 | Optimer Pharmaceuticals Inc | NEW ANTIBACTERIAL AGENTS |
| WO2007039914A2 (en) * | 2005-10-06 | 2007-04-12 | Alembic Limited | Novel polymorphs of telithromycin |
| WO2007049296A2 (en) * | 2005-10-28 | 2007-05-03 | Alembic Limited | Amorphous form of telithromycin |
| WO2007059307A2 (en) * | 2005-11-15 | 2007-05-24 | Teva Pharmaceutical Industries Ltd. | Crystalline and amorphous forms of telithromycin |
| WO2007069264A2 (en) * | 2005-12-15 | 2007-06-21 | Alembic Limited | Reference standards for determining the purity of telithromycin and processes therefor |
| GB0600238D0 (en) * | 2006-01-06 | 2006-02-15 | Sandoz Ag | Organic compounds |
| WO2008007388A1 (en) * | 2006-07-12 | 2008-01-17 | Alembic Limited | Novel process for the preparation of telithromycin |
| WO2008023383A1 (en) * | 2006-08-25 | 2008-02-28 | Alembic Limited | Novel process for the preparation of telithromycin |
| ES2306590B1 (es) * | 2006-12-15 | 2009-08-07 | Ercros Industrial,S .A. | Formas cristalinas i y ii de telitromicina. |
| ES2310121B1 (es) * | 2007-04-19 | 2009-09-11 | Ercros Industrial, S.A. | Nuevo proceso de sintesis de telitromicina. |
| US9453042B2 (en) | 2007-10-25 | 2016-09-27 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| WO2009053259A1 (en) * | 2007-10-25 | 2009-04-30 | Sandoz Ag | Process for the production of telithromycin |
| HRP20160222T1 (hr) | 2008-10-24 | 2016-04-08 | Cempra Pharmaceuticals, Inc. | Biozaštite uporabom makrolida koji sadrže triazol |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| EP2475253B1 (en) | 2009-09-10 | 2016-10-26 | Cempra Pharmaceuticals, Inc. | Methods for treating malaria, tuberculosis and mac diseases |
| JP5711352B2 (ja) | 2010-03-22 | 2015-04-30 | センプラ ファーマシューティカルズ，インコーポレイテッド | マクロライドの結晶形、およびその使用 |
| CN102917708B (zh) | 2010-05-20 | 2015-11-25 | 森普拉制药公司 | 制备大环内酯和酮内酯及其中间体的方法 |
| US9815863B2 (en) | 2010-09-10 | 2017-11-14 | Cempra Pharmaceuticals, Inc. | Hydrogen bond forming fluoro ketolides for treating diseases |
| IN2014DN08939A (sl) | 2012-03-27 | 2015-05-22 | Cempra Pharmaceuticals Inc | |
| CA2905975A1 (en) | 2013-03-14 | 2014-09-25 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| EP2968384A4 (en) | 2013-03-15 | 2017-02-15 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL114589A (en) * | 1990-11-21 | 1999-12-22 | Roussel Uclaf | Intermediates for the preparation of erythromycin derivatives |
| FR2719587B1 (fr) * | 1994-05-03 | 1996-07-12 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| FR2732684B1 (fr) * | 1995-04-06 | 1997-04-30 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
-
2005
- 2005-04-25 EP EP05775551A patent/EP1742957B1/en not_active Expired - Lifetime
- 2005-04-25 PL PL05775551T patent/PL1742957T3/pl unknown
- 2005-04-25 US US10/591,889 patent/US20070260066A1/en not_active Abandoned
- 2005-04-25 CA CA002559281A patent/CA2559281A1/en not_active Abandoned
- 2005-04-25 WO PCT/IN2005/000125 patent/WO2005105821A2/en not_active Ceased
- 2005-04-25 ES ES05775551T patent/ES2294733T3/es not_active Expired - Lifetime
- 2005-04-25 DE DE602005002475T patent/DE602005002475T2/de not_active Expired - Fee Related
- 2005-04-25 AU AU2005238313A patent/AU2005238313A1/en not_active Abandoned
- 2005-04-25 SI SI200530112T patent/SI1742957T1/sl unknown
- 2005-04-25 AT AT05775551T patent/ATE373009T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005238313A1 (en) | 2005-11-10 |
| PL1742957T3 (pl) | 2008-05-30 |
| ES2294733T3 (es) | 2008-04-01 |
| EP1742957B1 (en) | 2007-09-12 |
| DE602005002475D1 (de) | 2007-10-25 |
| WO2005105821A2 (en) | 2005-11-10 |
| CA2559281A1 (en) | 2005-11-10 |
| DE602005002475T2 (de) | 2008-05-29 |
| US20070260066A1 (en) | 2007-11-08 |
| EP1742957A2 (en) | 2007-01-17 |
| WO2005105821A3 (en) | 2006-04-27 |
| ATE373009T1 (de) | 2007-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI1742957T1 (sl) | Postopek za pripravo telitromicina | |
| MY142768A (en) | Gfat inhibitors | |
| NO20082338L (no) | Pyrimidinderivater for behandling av avvikende cellevekst | |
| NZ601786A (en) | Novel compounds and compositions and methods of use | |
| MX2008016423A (es) | Arilamidas sustituidas con tetrazol. | |
| WO2005082892A3 (en) | Triazole compounds as antibacterial agents and pharmaceutical compositions containing them | |
| NO20064077L (no) | Kemokinreseptorantagonister | |
| UA85698C2 (ru) | Хинолиновые промежуточные соединения для синтеза ингибиторов рецепторной тирозинкиназы и способ их получения | |
| IL176547A0 (en) | 1,3,5-trisubstituted 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity | |
| GEP20115171B (en) | Polymorphs of benzoate salt of 2-[[6-[(3r)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2h)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor | |
| WO2007084914A3 (en) | Phenoxy-substituted pyrimidines as adenosine receptor antagonists | |
| MY145696A (en) | 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-menthyl}-1-methyl-1h-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethylester-methanesulfonate and its use as a medicament | |
| TW200607801A (en) | Pyrimidine derivatives for the treatment of abnormal cell growth | |
| MY186650A (en) | Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives | |
| MXPA06013164A (es) | Derivados de pirimidina para el tratamiento de crecimiento de celulas anormal. | |
| NO20050921L (no) | Nye fysiologisk aktive substanser | |
| PT2049480E (pt) | Derivados de 2-arilindole como inibidores da mpges-i | |
| ATE374190T1 (de) | Tetrahydrochinazolinderivate als cfr-antagonisten | |
| DE602005019316D1 (en) | Aromatische etherderivate als thrombin-hemmer | |
| NO20070089L (no) | DPP-IV inhibitorer | |
| TNSN07006A1 (en) | Novel heterocyclic compounds | |
| NO20085052L (no) | 4-((fluorofenoksyl)fenylmetyl)piperidin metansulfonat: anvendelser, synteseprosess og farmasoytiske sammensetninger | |
| MX2010001938A (es) | Metodos para preparar compuestos basados en 4-fenil-6-(2,2,2-trifl uoro-1-feniletoxi)pirimidina. | |
| WO2008087654A3 (en) | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | |
| TW200702330A (en) | 3,4,5-Substituted piperidines |