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SI1463563T1 - Superoksidni dizmutazni mimetiki za zdravljenje očesnih motenj in bolezni - Google Patents

Superoksidni dizmutazni mimetiki za zdravljenje očesnih motenj in bolezni

Info

Publication number
SI1463563T1
SI1463563T1 SI200230808T SI200230808T SI1463563T1 SI 1463563 T1 SI1463563 T1 SI 1463563T1 SI 200230808 T SI200230808 T SI 200230808T SI 200230808 T SI200230808 T SI 200230808T SI 1463563 T1 SI1463563 T1 SI 1463563T1
Authority
SI
Slovenia
Prior art keywords
treatment
diseases
superoxide dismutase
ocular disorders
dismutase mimics
Prior art date
Application number
SI200230808T
Other languages
English (en)
Inventor
Robert J Collier Jr
Mark R Hellberg
Peter G Klimko
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of SI1463563T1 publication Critical patent/SI1463563T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI200230808T 2001-12-14 2002-12-06 Superoksidni dizmutazni mimetiki za zdravljenje očesnih motenj in bolezni SI1463563T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34038901P 2001-12-14 2001-12-14
EP02786915A EP1463563B1 (en) 2001-12-14 2002-12-06 Superoxide dismutase mimics for the treatment of ocular disorders and diseases
PCT/US2002/039037 WO2003051458A1 (en) 2001-12-14 2002-12-06 Superoxide dismutase mimics for the treatment of ocular disorders and diseases

Publications (1)

Publication Number Publication Date
SI1463563T1 true SI1463563T1 (sl) 2009-06-30

Family

ID=23333158

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200230808T SI1463563T1 (sl) 2001-12-14 2002-12-06 Superoksidni dizmutazni mimetiki za zdravljenje očesnih motenj in bolezni

Country Status (18)

Country Link
US (2) US7759333B2 (sl)
EP (1) EP1463563B1 (sl)
JP (1) JP2005513063A (sl)
KR (1) KR100951606B1 (sl)
CN (2) CN101092432A (sl)
AT (1) ATE422944T1 (sl)
BR (1) BR0214957A (sl)
CA (1) CA2470721C (sl)
CY (1) CY1108983T1 (sl)
DE (1) DE60231246D1 (sl)
DK (1) DK1463563T3 (sl)
ES (1) ES2319399T3 (sl)
MX (1) MXPA04005601A (sl)
PL (1) PL210225B1 (sl)
PT (1) PT1463563E (sl)
SI (1) SI1463563T1 (sl)
WO (1) WO2003051458A1 (sl)
ZA (1) ZA200404435B (sl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1463563B1 (en) * 2001-12-14 2009-02-18 Alcon, Inc. Superoxide dismutase mimics for the treatment of ocular disorders and diseases
BRPI0417549A (pt) * 2003-12-11 2007-03-27 Alcon Inc miméticos de superóxido dismutase para o tratamento de lesão de nervo óptico e retinal
US7803931B2 (en) 2004-02-12 2010-09-28 Archemix Corp. Aptamer therapeutics useful in the treatment of complement-related disorders
US8598150B1 (en) 2008-04-02 2013-12-03 Jonathan R. Brestoff Composition and method for affecting obesity and related conditions
US8987245B2 (en) 2008-04-02 2015-03-24 Jonathan R. Brestoff Parker Composition and method for affecting obesity and related conditions
NZ593536A (en) 2008-12-19 2013-07-26 Genentech Inc Quinoline derivatives and methods of use
PT2433640T (pt) 2010-09-24 2020-04-03 Omnivision Gmbh Composição compreendendo sod, luteína e zeaxantina
KR101214364B1 (ko) * 2011-02-15 2012-12-21 한림대학교 산학협력단 수퍼옥사이드 디스뮤테이즈 융합 단백질을 함유하는 안과 질환 예방 또는 치료용 약제학적 조성물
AU2012316397B2 (en) * 2011-09-26 2016-07-21 Galera Labs, Llc Methods for treatment of diseases
US20250381252A1 (en) * 2021-12-23 2025-12-18 Genofocus, Inc. Superoxide dismutase and uses thereof for preventing or treating macular degeneration
EP4527405A1 (en) * 2022-05-16 2025-03-26 Genofocus, Inc. Superoxide dismutase and uses thereof for preventing or treating diabetic retinopathy or uveitis

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5209926A (en) * 1990-06-12 1993-05-11 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US6127356A (en) * 1993-10-15 2000-10-03 Duke University Oxidant scavengers
SE9402816D0 (sv) 1994-08-24 1994-08-24 Pharmacia Ab Method and meams for drug administration
US6214817B1 (en) * 1997-06-20 2001-04-10 Monsanto Company Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity
US6180620B1 (en) * 1997-06-20 2001-01-30 G.D. Searle & Co. Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals
CA2309154C (en) 1997-11-03 2010-02-16 Duke University Substituted porphyrins
WO2000007584A2 (en) 1998-08-04 2000-02-17 Wisconsin Alumni Research Foundation Method of reducing retinal ganglion cell degeneration
GB9817845D0 (en) * 1998-08-17 1998-10-14 Glaxo Group Ltd Chemical compounds
WO2000023568A2 (en) 1998-10-06 2000-04-27 Albert Einstein College Of Medicine Of Yeshiva University Methods and compositions for decreasing mitochondrial overproduction of reactive oxygen species in cells
AU5048400A (en) 1999-05-27 2000-12-18 Monsanto Company Biomaterials modified with superoxide dismutase mimics
EP1463563B1 (en) 2001-12-14 2009-02-18 Alcon, Inc. Superoxide dismutase mimics for the treatment of ocular disorders and diseases

Also Published As

Publication number Publication date
JP2005513063A (ja) 2005-05-12
CY1108983T1 (el) 2014-07-02
PL369607A1 (en) 2005-05-02
DK1463563T3 (da) 2009-04-20
CN1620325A (zh) 2005-05-25
KR100951606B1 (ko) 2010-04-09
US20050032768A1 (en) 2005-02-10
ZA200404435B (en) 2006-05-31
DE60231246D1 (de) 2009-04-02
MXPA04005601A (es) 2004-12-06
BR0214957A (pt) 2004-12-14
PT1463563E (pt) 2009-03-19
WO2003051458A1 (en) 2003-06-26
EP1463563A1 (en) 2004-10-06
ES2319399T3 (es) 2009-05-07
CA2470721A1 (en) 2003-06-26
US20100204194A1 (en) 2010-08-12
PL210225B1 (pl) 2011-12-30
US7759333B2 (en) 2010-07-20
ATE422944T1 (de) 2009-03-15
HK1069785A1 (en) 2005-06-03
CA2470721C (en) 2011-07-12
KR20040063943A (ko) 2004-07-14
EP1463563B1 (en) 2009-02-18
US8003635B2 (en) 2011-08-23
AU2002351267A1 (en) 2003-06-30
AU2002351267B2 (en) 2007-04-05
CN101092432A (zh) 2007-12-26

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