SI1458861T1 - Ides, an igg-degrading enzyme of streptococcus pyogenes - Google Patents
Ides, an igg-degrading enzyme of streptococcus pyogenesInfo
- Publication number
- SI1458861T1 SI1458861T1 SI200231066T SI200231066T SI1458861T1 SI 1458861 T1 SI1458861 T1 SI 1458861T1 SI 200231066 T SI200231066 T SI 200231066T SI 200231066 T SI200231066 T SI 200231066T SI 1458861 T1 SI1458861 T1 SI 1458861T1
- Authority
- SI
- Slovenia
- Prior art keywords
- ides
- igg
- degrading enzyme
- streptococcus pyogenes
- pyogenes
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 241000193996 Streptococcus pyogenes Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
- C12N9/641—Cysteine endopeptidases (3.4.22)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0130228.0A GB0130228D0 (en) | 2001-12-18 | 2001-12-18 | Protein |
| EP02804912.0A EP1458861B1 (en) | 2001-12-18 | 2002-12-17 | Ides, an igg-degrading enzyme of streptococcus pyogenes |
| PCT/EP2002/014427 WO2003051914A2 (en) | 2001-12-18 | 2002-12-17 | Ides, an igg-degrading enzyme of streptococcus pyogenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1458861T1 true SI1458861T1 (en) | 2016-02-29 |
Family
ID=9927839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200231066T SI1458861T1 (en) | 2001-12-18 | 2002-12-17 | Ides, an igg-degrading enzyme of streptococcus pyogenes |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7666582B2 (en) |
| EP (2) | EP1458861B1 (en) |
| AU (1) | AU2002366285A1 (en) |
| DK (1) | DK1458861T3 (en) |
| ES (1) | ES2559274T3 (en) |
| GB (1) | GB0130228D0 (en) |
| HK (1) | HK1218308A1 (en) |
| SI (1) | SI1458861T1 (en) |
| WO (1) | WO2003051914A2 (en) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1686302A (en) | 2000-12-21 | 2002-07-01 | Shire Biochem Inc | Streptococcus pyogenes antigens and corresponding dna fragments |
| GB0130228D0 (en) | 2001-12-18 | 2002-02-06 | Hansa Medica Ab | Protein |
| GB0511769D0 (en) * | 2005-06-09 | 2005-07-20 | Hansa Medical Ab | Treatment |
| PL1901773T3 (en) * | 2005-06-09 | 2012-09-28 | Hansa Medical Ab | Use of the ides proteinase (from s. pyogenes) for treating autoimmune diseases and graft rejection |
| GB0624874D0 (en) * | 2006-12-13 | 2007-01-24 | Hansa Medical Ab | Treatment |
| US8691544B2 (en) * | 2007-05-04 | 2014-04-08 | Glycorex Transplantation Ab | Material for separation of a biomolecule |
| PL2188306T3 (en) * | 2007-08-10 | 2017-01-31 | Janssen Biotech, Inc. | Immunoglobulin cleavage fragments as disease indicators and compositions for detecting and binding such |
| US8501907B2 (en) * | 2007-08-10 | 2013-08-06 | Janssen Biotech, Inc. | Immunoglobulin cleavage fragments as disease indicators and compositions for detecting and binding such |
| DK2190984T3 (en) | 2007-09-14 | 2013-12-02 | Genovis Ab | Methods and kits for purifying and detecting glycosylated IgG |
| CA2709029A1 (en) | 2007-12-21 | 2009-07-02 | Bianca Eser | Stability testing of antibodies |
| EP2304439A4 (en) * | 2008-05-29 | 2012-07-04 | Nuclea Biotechnologies Llc | Anti-phospho-akt antibodies |
| JP5461586B2 (en) * | 2009-02-09 | 2014-04-02 | ロシュ グリクアート アクチェンゲゼルシャフト | Immunoglobulin glycosylation pattern analysis |
| EP2498812A4 (en) * | 2009-11-13 | 2013-05-22 | Bengt Guss | Immunizing composition for reducing streptococcal infections |
| CA2822366A1 (en) | 2010-12-23 | 2012-06-28 | Janssen Biotech, Inc. | Active protease-resistant antibody fc mutants |
| GB201103780D0 (en) | 2011-03-04 | 2011-04-20 | Hansa Medical Ab | Treatment for ige-mediated disease |
| GB201115841D0 (en) | 2011-09-13 | 2011-10-26 | Genovis Ab | Protein and method |
| GB201201314D0 (en) | 2012-01-26 | 2012-03-07 | Isis Innovation | Composition |
| GB201316744D0 (en) * | 2013-09-20 | 2013-11-06 | Genovis Ab | Method |
| GB201502306D0 (en) * | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
| GB201502305D0 (en) | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
| WO2017134274A1 (en) * | 2016-02-04 | 2017-08-10 | Ulrich Von Pawel-Rammingen | New streptococcal proteases |
| WO2017205741A1 (en) | 2016-05-27 | 2017-11-30 | Genentech, Inc. | Bioanalytical method for the characterization of site-specific antibody-drug conjugates |
| WO2018093868A1 (en) * | 2016-11-16 | 2018-05-24 | University Of Florida Research Foundation, Inc. | Immunoglobulin proteases, compositions, and uses thereof |
| CA3133388A1 (en) | 2019-03-14 | 2020-09-17 | Janssen Biotech, Inc. | Methods for producing anti-tnf antibody compositions |
| MA55282A (en) | 2019-03-14 | 2022-01-19 | Janssen Biotech Inc | MANUFACTURING METHODS FOR THE PRODUCTION OF ANTI-TNF ANTIBODY COMPOSITIONS |
| CN113825765A (en) | 2019-03-14 | 2021-12-21 | 詹森生物科技公司 | Method for producing anti-IL 12/IL23 antibody composition |
| CA3133383A1 (en) | 2019-03-14 | 2020-09-17 | Janssen Biotech, Inc. | Methods for producing anti-tnf antibody compositions |
| JP2022548197A (en) | 2019-12-06 | 2022-11-17 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | ANTI-VEGF PROTEIN COMPOSITION AND METHOD FOR MANUFACTURE THEREOF |
| GB202002072D0 (en) * | 2020-02-14 | 2020-04-01 | Hansa Biopharma AB | immunoglobulin detection and associated therapies |
| CN115803009A (en) | 2020-05-08 | 2023-03-14 | 瑞泽恩制药公司 | VEGF traps and microwells and methods for treating ocular diseases and cancer |
| GB202007431D0 (en) | 2020-05-19 | 2020-07-01 | Hansa Biopharma AB | Cysteine protease |
| US20230374542A1 (en) | 2020-10-07 | 2023-11-23 | Asklepios Biopharmaceutical, Inc. | Therapeutic adeno-associated virus delivery of fukutin related protein (fkrp) for treating dystroglycanopathy. disorders including limb girdle 21 (lgmd21) |
| WO2022221529A1 (en) | 2021-04-16 | 2022-10-20 | Asklepios Biopharmaceutical, Inc. | Rational polyploid aav virions that cross the blood brain barrier and elicit reduced humoral response |
| EP4079848A1 (en) | 2021-04-22 | 2022-10-26 | Genovis Ab | Immunoglobulin cleaving enzyme |
| WO2022266044A1 (en) * | 2021-06-15 | 2022-12-22 | The University Of North Carolina At Chapel Hill | Methods and compositions for depleting antibodies |
| JP2024526736A (en) | 2021-07-13 | 2024-07-19 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | De novo protein N-terminal sequencing by site-selective dimethylation |
| WO2024057095A1 (en) | 2022-09-14 | 2024-03-21 | Genovis Ab | Mutant protease |
| CN118853710A (en) * | 2022-11-08 | 2024-10-29 | 上海泰昶生物技术有限公司 | Engineering strain and process for producing immunoglobulin G degrading enzyme |
| CN115998690B (en) * | 2022-11-10 | 2024-07-26 | 上海泰昶生物技术有限公司 | Freeze-dried preparation containing immunoglobulin G degrading enzyme and preparation process thereof |
| US12091694B2 (en) | 2022-11-18 | 2024-09-17 | Seismic Therapeutic, Inc. | Fc fusion molecules and uses thereof |
| EP4646476A1 (en) | 2023-01-06 | 2025-11-12 | Seismic Therapeutic, Inc. | Protease variants and uses thereof |
| WO2024206953A2 (en) * | 2023-03-29 | 2024-10-03 | Taktos Therapeutics Inc. | Ides variant proteins and methods of using the same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2233977B (en) * | 1989-01-04 | 1993-03-31 | Michael Kehoe | Cytolytic streptolysin o mutants and uses |
| US5976542A (en) | 1996-09-23 | 1999-11-02 | New England Medical Center | Compositions and methods for treatment of streptococcus pneumoniae infection |
| ATE394489T1 (en) * | 1998-12-23 | 2008-05-15 | Id Biomedical Corp | STREPTOCOCCUS ANTIGENS |
| WO2002034771A2 (en) * | 2000-10-27 | 2002-05-02 | Chiron Srl | Nucleic acids and proteins from streptococcus groups a & b |
| AU1686302A (en) * | 2000-12-21 | 2002-07-01 | Shire Biochem Inc | Streptococcus pyogenes antigens and corresponding dna fragments |
| GB0130228D0 (en) | 2001-12-18 | 2002-02-06 | Hansa Medica Ab | Protein |
-
2001
- 2001-12-18 GB GBGB0130228.0A patent/GB0130228D0/en not_active Ceased
-
2002
- 2002-12-17 EP EP02804912.0A patent/EP1458861B1/en not_active Expired - Lifetime
- 2002-12-17 EP EP15170905.2A patent/EP2949749A1/en not_active Withdrawn
- 2002-12-17 US US10/499,143 patent/US7666582B2/en not_active Expired - Lifetime
- 2002-12-17 ES ES02804912.0T patent/ES2559274T3/en not_active Expired - Lifetime
- 2002-12-17 SI SI200231066T patent/SI1458861T1/en unknown
- 2002-12-17 AU AU2002366285A patent/AU2002366285A1/en not_active Abandoned
- 2002-12-17 DK DK02804912.0T patent/DK1458861T3/en active
- 2002-12-17 WO PCT/EP2002/014427 patent/WO2003051914A2/en not_active Ceased
-
2007
- 2007-04-03 US US11/730,659 patent/US20070237784A1/en not_active Abandoned
-
2016
- 2016-06-01 HK HK16106218.5A patent/HK1218308A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002366285A8 (en) | 2003-06-30 |
| US7666582B2 (en) | 2010-02-23 |
| WO2003051914A2 (en) | 2003-06-26 |
| EP1458861B1 (en) | 2015-11-04 |
| HK1218308A1 (en) | 2017-02-10 |
| WO2003051914A3 (en) | 2004-03-04 |
| US20050119464A1 (en) | 2005-06-02 |
| EP1458861A2 (en) | 2004-09-22 |
| EP2949749A1 (en) | 2015-12-02 |
| ES2559274T3 (en) | 2016-02-11 |
| AU2002366285A1 (en) | 2003-06-30 |
| GB0130228D0 (en) | 2002-02-06 |
| US20070237784A1 (en) | 2007-10-11 |
| DK1458861T3 (en) | 2016-02-01 |
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