SI1140148T1 - Stabilna formulacija raztopine glukagonu podobnega peptida-1 - Google Patents

Stabilna formulacija raztopine glukagonu podobnega peptida-1

Info

Publication number: SI1140148T1
Authority: SI; Slovenia
Prior art keywords: glucagon; shelf; peptide; solution formulation; stable solution
Prior art date: 1998-12-22

Application number

SI9930857T

Other languages

English (en)

Inventor

Mark L Brader

Allen H Pekar

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-22

Filing date

1999-12-21

Publication date

2006-04-30

1999-12-21 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1999-12-21 Priority claimed from EP99967463A external-priority patent/EP1140148B1/en

2006-04-30 Publication of SI1140148T1 publication Critical patent/SI1140148T1/sl

Links

DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 title 1
101800000224 Glucagon-like peptide 1 Proteins 0.000 title 1
102100040918 Pro-glucagon Human genes 0.000 title 1
238000009472 formulation Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Dermatology (AREA)
Emergency Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SI9930857T 1998-12-22 1999-12-21 Stabilna formulacija raztopine glukagonu podobnega peptida-1 SI1140148T1 (sl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11349998P	1998-12-22	1998-12-22
EP99967463A EP1140148B1 (en)	1998-12-22	1999-12-21	Shelf-stable solution formulation of glucagon-like peptide-1
PCT/US1999/030395 WO2000037098A1 (en)	1998-12-22	1999-12-21	Shelf-stable formulation of glucagon-like peptide-1

Publications (1)

Publication Number	Publication Date
SI1140148T1 true SI1140148T1 (sl)	2006-04-30

Family

ID=35140603

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9930857T SI1140148T1 (sl)	1998-12-22	1999-12-21	Stabilna formulacija raztopine glukagonu podobnega peptida-1

Country Status (2)

Country	Link
EP (1)	EP1600162A1 (sl)
SI (1)	SI1140148T1 (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9649382B2 (en)	2005-01-14	2017-05-16	Camurus Ab	Topical bioadhesive formulations
ATE501710T1 (de)	2005-01-14	2011-04-15	Camurus Ab	Somatostatin-analog-formulierungen
ATE462409T1 (de)	2005-01-14	2010-04-15	Camurus Ab	Topische bioadhäsive formulierungen
CA2595385C (en)	2005-01-21	2011-01-25	Camurus Ab	Pharmaceutical lipid compositions
CA2609810C (en)	2005-06-06	2012-05-22	Camurus Ab	Glp-1 analogue formulations
GB0711656D0 (en)	2007-06-15	2007-07-25	Camurus Ab	Formulations
GB0716385D0 (en)	2007-08-22	2007-10-03	Camurus Ab	Formulations
GB0815435D0 (en)	2008-08-22	2008-10-01	Camurus Ab	Formulations
IN2014DN09831A (sl)	2012-05-25	2015-08-07	Camurus Ab
CN103405753B (zh) *	2013-08-13	2016-05-11	上海仁会生物制药股份有限公司	稳定的促胰岛素分泌肽水针药物组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1987006941A1 (en) *	1986-05-05	1987-11-19	The General Hospital Corporation	Insulinotropic hormone
US5118666A (en)	1986-05-05	1992-06-02	The General Hospital Corporation	Insulinotropic hormone
CA2073856C (en)	1990-01-24	2002-12-03	Douglas I. Buckley	Glp-1 analogs useful for diabetes treatment
US5705483A (en) *	1993-12-09	1998-01-06	Eli Lilly And Company	Glucagon-like insulinotropic peptides, compositions and methods
GB9409496D0 (en) *	1994-05-12	1994-06-29	London Health Ass	Method for improving glycaemic control in diabetes
US5512549A (en)	1994-10-18	1996-04-30	Eli Lilly And Company	Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
AU4298596A (en) *	1994-12-23	1996-07-19	Novo Nordisk A/S	Protracted glp-1 compositions

1999
- 1999-12-21 SI SI9930857T patent/SI1140148T1/sl unknown
- 1999-12-21 EP EP05107763A patent/EP1600162A1/en not_active Withdrawn

Also Published As

Publication number	Publication date
EP1600162A1 (en)	2005-11-30

Publication	Publication Date	Title
IL136377A0 (en)	2001-06-14	Glucagon-like peptide-1 crystals
HUP9900604A3 (en)	2001-01-29	New peptide compounds that are analogues of the glucagon-like p
EP1049486A4 (en)	2006-01-04	GLP-1 FORMULATIONS
IL153453A0 (en)	2003-07-06	Glucagon-like peptide-1 analogs
HUP9903714A3 (en)	2000-07-28	Glp-1 derivatives
PT1019077E (pt)	2008-02-21	Novos compostos agonistas de exendina
GB2331208B (en)	2002-12-11	Path restoration of networks
EP1017770A4 (en)	2002-04-24	AQUEOUS RINSE AID
AU6586298A (en)	1998-10-22	Glucagon-like peptide-1 analogs
SG82642A1 (en)	2001-08-21	Short circuit welder
IL132012A0 (en)	2001-03-19	Substituted benzamides
HU9800555D0 (en)	1998-05-28	Substituted amino-compounds and their use as analgetic agent
HUP0003428A3 (en)	2001-12-28	Use of leptin antagonists for the treatment of diabetes
SI1140148T1 (sl)	2006-04-30	Stabilna formulacija raztopine glukagonu podobnega peptida-1
HUP0104193A3 (en)	2003-07-28	An improved process for the preparation of new antidiabetic agents
HU9801894D0 (en)	1998-10-28	Antiarrythmic agent for treating congestive heart failure
ZA200304047B (en)	2004-04-28	Analogues of GLP-1.
TW335707U (en)	1998-07-01	Improved structure of flipper
HU1625U (en)	1999-10-28	Electrical joint arrangement
TW371522U (en)	1999-10-01	Card-rejection mechanism of connector
HU1000133D0 (en)	2010-05-28	Glp-1 derivatives
GB9810681D0 (en)	1998-07-15	Hormone
TW471265U (en)	2002-01-01	Improved structure of molting machine for garlic
EP1011665A4 (en)	2001-09-12	HETEROCYCLIC AGENTS
GB9711302D0 (en)	1997-07-30	Highly stable electrical oscillator