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SI0996629T1 - Analogi glikoproteinskega hormona povezanega z disulfidi, priprava in uporaba - Google Patents

Analogi glikoproteinskega hormona povezanega z disulfidi, priprava in uporaba

Info

Publication number
SI0996629T1
SI0996629T1 SI9830857T SI9830857T SI0996629T1 SI 0996629 T1 SI0996629 T1 SI 0996629T1 SI 9830857 T SI9830857 T SI 9830857T SI 9830857 T SI9830857 T SI 9830857T SI 0996629 T1 SI0996629 T1 SI 0996629T1
Authority
SI
Slovenia
Prior art keywords
preparation
hormone analogs
glycoprotein hormone
disulfide crosslinked
crosslinked glycoprotein
Prior art date
Application number
SI9830857T
Other languages
English (en)
Inventor
William R Moyle
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21967404&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI0996629(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of SI0996629T1 publication Critical patent/SI0996629T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SI9830857T 1997-06-25 1998-06-25 Analogi glikoproteinskega hormona povezanega z disulfidi, priprava in uporaba SI0996629T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5078497P 1997-06-25 1997-06-25
EP98930477A EP0996629B1 (en) 1997-06-25 1998-06-25 Disulfide crosslinked glycoprotein hormone analogs, their preparation and use
PCT/US1998/013070 WO1998058957A2 (en) 1997-06-25 1998-06-25 Disulfide cross-linked glycoprotein hormone analogs, their preparation and use

Publications (1)

Publication Number Publication Date
SI0996629T1 true SI0996629T1 (sl) 2006-12-31

Family

ID=21967404

Family Applications (2)

Application Number Title Priority Date Filing Date
SI9830857T SI0996629T1 (sl) 1997-06-25 1998-06-25 Analogi glikoproteinskega hormona povezanega z disulfidi, priprava in uporaba
SI9830920T SI1775346T1 (sl) 1997-06-25 1998-06-25 Analogi glikoproteinskih hormonov, premreĺ˝eni z disulfidom, njihova priprava in uporaba

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI9830920T SI1775346T1 (sl) 1997-06-25 1998-06-25 Analogi glikoproteinskih hormonov, premreĺ˝eni z disulfidom, njihova priprava in uporaba

Country Status (20)

Country Link
US (1) US8530190B1 (sl)
EP (2) EP1775346B1 (sl)
JP (3) JP3950484B2 (sl)
KR (2) KR100706469B1 (sl)
CN (3) CN100404551C (sl)
AR (1) AR013139A1 (sl)
AT (2) ATE335000T1 (sl)
AU (1) AU747179B2 (sl)
BR (1) BR9810478A (sl)
CA (1) CA2293731C (sl)
CY (2) CY1105763T1 (sl)
DE (2) DE69841063D1 (sl)
DK (2) DK0996629T3 (sl)
ES (2) ES2268781T3 (sl)
HU (1) HU227908B1 (sl)
IL (2) IL133686A0 (sl)
PT (2) PT996629E (sl)
SI (2) SI0996629T1 (sl)
WO (1) WO1998058957A2 (sl)
ZA (1) ZA985545B (sl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716428B1 (en) * 1999-10-06 2004-04-06 The Ohio State University Research Foundation Antigenic modification of polypeptides
EP1261622B1 (en) * 2000-02-22 2007-03-07 Applied Research Systems ARS Holding N.V. Purified recombinant hlh having a specific bioactivity and process for purification thereof
AU2000280019A1 (en) * 2000-10-06 2002-04-22 Regeneron Pharmaceuticals, Inc. Polypeptides, methods of making, and uses thereof
CA2466595A1 (en) * 2001-11-08 2003-05-15 William R. Moyle Protein knobs
CA2612613A1 (en) 2005-09-14 2007-03-22 Mara Rossi Method for the determination of poloxamers
EP1981908B1 (en) * 2006-01-17 2010-11-10 Merck Serono SA Novel fsh glycosylation variant d3n
CN101250531B (zh) * 2006-11-27 2013-04-24 株式会社Lg生命科学 一核苷酸序列、包含该序列的表达载体、该载体转化的动物细胞及利用该细胞生产人fsh的方法
KR101573773B1 (ko) 2008-02-08 2015-12-02 바이오제너릭스 게엠베하 Ｆｓｈ의 액체 포뮬레이션
CN101347613B (zh) * 2008-09-17 2011-10-26 上海天伟生物制药有限公司 几乎不含亚基的糖蛋白的组合物及其制备方法
CN102292349B (zh) * 2009-01-22 2016-04-13 诺沃—诺迪斯克保健股份有限公司 稳定的生长激素化合物
CA2755927A1 (en) 2009-04-01 2010-10-14 Biogenerix Ag Method for purifying recombinant fsh
TWI604850B (zh) 2009-10-05 2017-11-11 菲瑞茵國際中心股份有限公司 藥學製劑
EP2325194A1 (en) 2009-11-24 2011-05-25 Glycotope GmbH Process for the purification of glycoproteins
MX345736B (es) 2010-01-22 2017-02-14 Novo Nordisk Healthcare Ag Hormonas de crecimiento con eficacia in vivo prolongada.
US9211342B2 (en) 2010-01-22 2015-12-15 Novo Nordisk Healthcare Ag Stable growth hormone compounds resistant to proteolytic degradation
US9757469B2 (en) 2011-03-31 2017-09-12 Ferring B.V. Pharmaceutical preparation
PT2880164T (pt) * 2012-07-30 2019-06-05 Trophogen Inc Superagonistas de ação prolongada de hormonas glicoproteicas
CN105120887A (zh) 2013-04-05 2015-12-02 诺和诺德保健股份有限公司 生长激素化合物制剂
WO2022072677A1 (en) * 2020-09-30 2022-04-07 The University Of North Carolina At Chapel Hill Engineered stable lactate oxidoreductases, compositions, devices, kits and uses thereof
WO2022150878A1 (en) * 2021-01-13 2022-07-21 University Of Newcastle Compositions and methods of using targeting peptides and nanopharmaceuticals for the sterilization of cats and dogs
CN119768414A (zh) * 2022-11-10 2025-04-04 康立泰生物医药(青岛)有限公司 聚乙二醇定点修饰异源聚体蛋白或多肽及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079230A (en) * 1988-09-12 1992-01-07 Pitman-Moore, Inc. Stable bioactive somatotropins
US5691455A (en) * 1995-10-24 1997-11-25 Akzo Nobel N.V. Gonadotropins with non-native disulfide bridges
US20090209453A1 (en) * 2005-04-13 2009-08-20 University Of Medicine And Dentistry Of New Jersey Glycoprotein Hormone Analogs

Also Published As

Publication number Publication date
JP4279768B2 (ja) 2009-06-17
EP1775346A1 (en) 2007-04-18
JP2005162734A (ja) 2005-06-23
DK1775346T3 (da) 2009-09-28
HUP0100681A3 (en) 2004-03-01
KR100706469B1 (ko) 2007-04-10
CY1109439T1 (el) 2014-08-13
HUP0100681A1 (hu) 2001-06-28
KR100560279B1 (ko) 2006-03-10
HK1033149A1 (en) 2001-08-17
JP2007016040A (ja) 2007-01-25
DK0996629T3 (da) 2006-12-04
DE69835433T2 (de) 2007-03-08
EP1775346B1 (en) 2009-08-12
JP4278668B2 (ja) 2009-06-17
ATE439439T1 (de) 2009-08-15
CN1269833A (zh) 2000-10-11
DE69841063D1 (de) 2009-09-24
JP2001521402A (ja) 2001-11-06
PT1775346E (pt) 2009-08-25
CN100404551C (zh) 2008-07-23
HU227908B1 (en) 2012-05-29
JP3950484B2 (ja) 2007-08-01
ATE335000T1 (de) 2006-08-15
EP0996629B1 (en) 2006-08-02
IL133686A0 (en) 2001-04-30
AU7986198A (en) 1999-01-04
CN1302010C (zh) 2007-02-28
SI1775346T1 (sl) 2009-10-31
CN1197968C (zh) 2005-04-20
BR9810478A (pt) 2000-09-12
KR20020006720A (ko) 2002-01-26
WO1998058957A3 (en) 1999-04-22
CA2293731C (en) 2010-01-12
AU747179B2 (en) 2002-05-09
ES2268781T3 (es) 2007-03-16
AR013139A1 (es) 2000-12-13
KR20040039421A (ko) 2004-05-10
CA2293731A1 (en) 1998-12-30
CY1105763T1 (el) 2011-02-02
ES2332931T3 (es) 2010-02-15
ZA985545B (en) 1999-04-01
US8530190B1 (en) 2013-09-10
CN1548459A (zh) 2004-11-24
IL133686A (en) 2007-07-24
CN1548458A (zh) 2004-11-24
WO1998058957A2 (en) 1998-12-30
PT996629E (pt) 2006-12-29
DE69835433D1 (de) 2006-09-14
EP0996629A2 (en) 2000-05-03
WO1998058957A9 (en) 1999-06-03

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