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SG32689G - Trinitroglycerol sustained release vehicles and preparation therefrom - Google Patents

Trinitroglycerol sustained release vehicles and preparation therefrom

Info

Publication number
SG32689G
SG32689G SG326/89A SG32689A SG32689G SG 32689 G SG32689 G SG 32689G SG 326/89 A SG326/89 A SG 326/89A SG 32689 A SG32689 A SG 32689A SG 32689 G SG32689 G SG 32689G
Authority
SG
Singapore
Prior art keywords
trinitroglycerol
sustained release
release vehicles
preparation therefrom
therefrom
Prior art date
Application number
SG326/89A
Other languages
English (en)
Original Assignee
Key Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Key Pharma filed Critical Key Pharma
Publication of SG32689G publication Critical patent/SG32689G/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG326/89A 1981-07-08 1989-05-18 Trinitroglycerol sustained release vehicles and preparation therefrom SG32689G (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28138981A 1981-07-08 1981-07-08
PCT/US1982/000928 WO1983000093A1 (fr) 1981-07-08 1982-07-08 Vehicules a liberation soutenue de trinitroglycerol et leur preparation

Publications (1)

Publication Number Publication Date
SG32689G true SG32689G (en) 1989-09-22

Family

ID=23077093

Family Applications (1)

Application Number Title Priority Date Filing Date
SG326/89A SG32689G (en) 1981-07-08 1989-05-18 Trinitroglycerol sustained release vehicles and preparation therefrom

Country Status (6)

Country Link
EP (1) EP0083371B1 (fr)
JP (1) JPS58501078A (fr)
CA (1) CA1218604A (fr)
DE (1) DE3273880D1 (fr)
SG (1) SG32689G (fr)
WO (1) WO1983000093A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696821A (en) * 1983-10-11 1987-09-29 Warner-Lambert Company Transdermal delivery system for administration of nitroglycerin
US5202125A (en) * 1990-12-10 1993-04-13 Theratech, Inc. Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
DE4101873C2 (de) * 1991-01-23 1993-12-09 Isis Pharma Gmbh Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände
US5624960A (en) * 1991-01-23 1997-04-29 Isis Pharma Gmbh Orally administrable drugs for the treatment of central dopamine deficiency conditions
JP3628809B2 (ja) * 1996-06-10 2005-03-16 アルケア株式会社 薬剤徐放性医療用配合物及びその製造方法
CN100523091C (zh) * 2003-04-15 2009-08-05 英诺格尔股份公司 聚合物网络

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2155658A (en) * 1936-01-08 1939-04-25 Chemische Forschungs Gmbh Surgical and medical preparations
US2693438A (en) * 1951-02-21 1954-11-02 Norwich Pharma Co Preformed, nonadherent films for application to open lesions
BE638231A (fr) * 1962-03-16
BE653682A (fr) * 1963-02-19
GB1083896A (en) * 1964-04-30 1967-09-20 Dunster Lab Ltd Vehicles for administering drugs
FR1409082A (fr) * 1964-09-25 1965-08-20 Dynamit Nobel Ag Procédé de gélatinisation d'esters nitriques fluides et de composés nitro-aromatiques fluides
GB1090184A (en) * 1964-10-12 1967-11-08 Dynamit Nobel Ag Improvements in or relating to explosive compositions
JPS4942889B1 (fr) * 1966-01-13 1974-11-18
US3789119A (en) * 1971-06-01 1974-01-29 Parke Davis & Co Stabilized molded sublingual nitroglycerin tablets
US3742951A (en) * 1971-08-09 1973-07-03 Alza Corp Bandage for controlled release of vasodilators
US4091091A (en) * 1973-11-08 1978-05-23 Eli Lilly And Company Stabilized nitroglycerin tablets
JPS5138412A (en) * 1974-09-24 1976-03-31 Nippon Kayaku Kk Kokoseizai no seiho
US3972995A (en) * 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
SU806037A1 (ru) * 1978-04-06 1981-02-23 Всесоюзный Кардиологический Научныйцентр Amh Cccp Антиангинальное средство
US4210633A (en) * 1978-10-20 1980-07-01 Eli Lilly And Company Flurandrenolide film formulation
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
IL59063A (en) * 1979-01-11 1983-12-30 Key Pharma Polymeric diffusion matrix for release of pharmaceutical dosage
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4336243A (en) * 1980-08-11 1982-06-22 G. D. Searle & Co. Transdermal nitroglycerin pad

Also Published As

Publication number Publication date
CA1218604A (fr) 1987-03-03
EP0083371A4 (fr) 1983-12-19
JPS58501078A (ja) 1983-07-07
DE3273880D1 (en) 1986-11-27
EP0083371A1 (fr) 1983-07-13
EP0083371B1 (fr) 1986-10-22
WO1983000093A1 (fr) 1983-01-20

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