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SG178880A1 - Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use - Google Patents

Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use

Info

Publication number
SG178880A1
SG178880A1 SG2012013264A SG2012013264A SG178880A1 SG 178880 A1 SG178880 A1 SG 178880A1 SG 2012013264 A SG2012013264 A SG 2012013264A SG 2012013264 A SG2012013264 A SG 2012013264A SG 178880 A1 SG178880 A1 SG 178880A1
Authority
SG
Singapore
Prior art keywords
hydrates
pharmaceuticals
compounds
novel crystalline
fluoroglycoside
Prior art date
Application number
SG2012013264A
Inventor
David Rigal
Franceska Fischer
Bernd Becker
Martin Feth
Norbert Nagel
Bruno Baumgartner
Martin Broeckelmann
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of SG178880A1 publication Critical patent/SG178880A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to crystalline hydrates of the formula (I) in which n has a value of from 2.1 to 2.5. The compound is suitable, for example, as an antidiabetic.
SG2012013264A 2009-08-26 2010-08-26 Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use SG178880A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09290650 2009-08-26
PCT/EP2010/062461 WO2011023754A1 (en) 2009-08-26 2010-08-26 Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use

Publications (1)

Publication Number Publication Date
SG178880A1 true SG178880A1 (en) 2012-04-27

Family

ID=41426365

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2012013264A SG178880A1 (en) 2009-08-26 2010-08-26 Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use

Country Status (16)

Country Link
US (1) US8785608B2 (en)
EP (1) EP2470552B1 (en)
JP (1) JP2013503135A (en)
KR (1) KR20120060207A (en)
CN (1) CN102482312A (en)
AU (1) AU2010288523A1 (en)
BR (1) BR112012003973A2 (en)
CA (1) CA2771278A1 (en)
DK (1) DK2470552T3 (en)
ES (1) ES2443016T3 (en)
IL (1) IL218225A0 (en)
MX (1) MX2012001729A (en)
PT (1) PT2470552E (en)
RU (1) RU2012111354A (en)
SG (1) SG178880A1 (en)
WO (1) WO2011023754A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101721831B1 (en) * 2014-11-06 2017-03-31 주식회사 종근당 Pharmaceutical Compositions Comprising Lobeglitazone for Oral Administration
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
EP4151210A3 (en) * 2020-01-10 2023-06-14 Harmony Biosciences, LLC Pyridine-carboline derivatives as mchr1 antagonists for use in therapy

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