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SG153727A1 - Substituted pyridinones as modulators of p38 map kinase - Google Patents

Substituted pyridinones as modulators of p38 map kinase

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Publication number
SG153727A1
SG153727A1 SG200808207-5A SG2008082075A SG153727A1 SG 153727 A1 SG153727 A1 SG 153727A1 SG 2008082075 A SG2008082075 A SG 2008082075A SG 153727 A1 SG153727 A1 SG 153727A1
Authority
SG
Singapore
Prior art keywords
compounds
map kinase
modulators
substituted pyridinones
disclosed
Prior art date
Application number
SG200808207-5A
Inventor
Shuang Liu
Ian L Scott
Kevin F Mcgee
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Priority to SG200808207-5A priority Critical patent/SG153727A1/en
Publication of SG153727A1 publication Critical patent/SG153727A1/en

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Abstract

Disclosed are compounds of Formula (1) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.
SG200808207-5A 2003-02-14 2003-02-14 Substituted pyridinones as modulators of p38 map kinase SG153727A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG200808207-5A SG153727A1 (en) 2003-02-14 2003-02-14 Substituted pyridinones as modulators of p38 map kinase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG200808207-5A SG153727A1 (en) 2003-02-14 2003-02-14 Substituted pyridinones as modulators of p38 map kinase

Publications (1)

Publication Number Publication Date
SG153727A1 true SG153727A1 (en) 2009-07-29

Family

ID=40901939

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200808207-5A SG153727A1 (en) 2003-02-14 2003-02-14 Substituted pyridinones as modulators of p38 map kinase

Country Status (1)

Country Link
SG (1) SG153727A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997010712A1 (en) * 1995-09-19 1997-03-27 Margolin Solomon B Inhibition of tumor necrosis factor alpha

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997010712A1 (en) * 1995-09-19 1997-03-27 Margolin Solomon B Inhibition of tumor necrosis factor alpha

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