[go: up one dir, main page]

SG158108A1 - Production of beta-lactam antibiotics by genetically modified non- naturally producing microorganisms - Google Patents

Production of beta-lactam antibiotics by genetically modified non- naturally producing microorganisms

Info

Publication number
SG158108A1
SG158108A1 SG200908083-9A SG2009080839A SG158108A1 SG 158108 A1 SG158108 A1 SG 158108A1 SG 2009080839 A SG2009080839 A SG 2009080839A SG 158108 A1 SG158108 A1 SG 158108A1
Authority
SG
Singapore
Prior art keywords
beta
production
genetically modified
lactam
modified non
Prior art date
Application number
SG200908083-9A
Other languages
English (en)
Inventor
Marco Alexander Van Den Berg
Roelof Ary Lans Bovenberg
Hendrik Jan Noorman
Bastiaan Romein
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of SG158108A1 publication Critical patent/SG158108A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG200908083-9A 2004-12-10 2005-12-08 Production of beta-lactam antibiotics by genetically modified non- naturally producing microorganisms SG158108A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04106471 2004-12-10

Publications (1)

Publication Number Publication Date
SG158108A1 true SG158108A1 (en) 2010-01-29

Family

ID=34930032

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200908083-9A SG158108A1 (en) 2004-12-10 2005-12-08 Production of beta-lactam antibiotics by genetically modified non- naturally producing microorganisms

Country Status (8)

Country Link
US (1) US20080131925A1 (fr)
EP (1) EP1819813A2 (fr)
KR (1) KR20070085955A (fr)
CN (1) CN101098963A (fr)
BR (1) BRPI0518399A2 (fr)
MX (1) MX2007006780A (fr)
SG (1) SG158108A1 (fr)
WO (1) WO2006061425A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2084270T1 (sl) * 2006-10-05 2014-03-31 Dsm Sinochem Pharmaceuticals Netherlands B.V. Izdelava beta - laktam antibiotikov
EP2080801A1 (fr) * 2008-01-21 2009-07-22 Technical University of Denmark Production de peptides non ribosomales dans les saccharomyces
EP2123772A1 (fr) * 2008-04-29 2009-11-25 DSM IP Assets B.V. Souches produisant des antibiotiques bêta-lactamines
EP2376619A4 (fr) 2008-12-15 2012-07-04 Greenlight Biosciences Inc Procédés de commande de flux dans des voies métaboliques
WO2010074760A1 (fr) * 2008-12-22 2010-07-01 Greenlight Biosciences Compositions et procédés pour la production d'un composé
US8956833B2 (en) 2010-05-07 2015-02-17 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
EP2611922A1 (fr) 2010-08-31 2013-07-10 Greenlight Biosciences, Inc. Procédés pour la commande de flux dans des voies métaboliques par manipulation de protéase
SG2014014377A (en) 2011-09-09 2014-05-29 Greenlight Biosciences Inc Cell-free preparation of carbapenems
CA2919383A1 (fr) 2013-08-05 2015-02-12 Greenlight Biosciences, Inc. Proteines produites par genie genetique avec site de clivage par les proteases
CR20170485A (es) 2015-03-30 2018-02-05 Greenlight Biosciences Inc Producción de ácido ribonucleico libre de células
US10954541B2 (en) 2016-04-06 2021-03-23 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
MX2019008159A (es) 2017-01-06 2019-12-09 Greenlight Biosciences Inc Producción acelular de azúcares.
SG11202003192UA (en) 2017-10-11 2020-05-28 Greenlight Biosciences Inc Methods and compositions for nucleoside triphosphate and ribonucleic acid production

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85535A (en) * 1987-03-04 1994-02-27 Lilly Co Eli Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase and deacetylcephalosporin c synthetase
US6258555B1 (en) * 1987-12-09 2001-07-10 Beecham Group P.L.C. DNA encoding ACV synthetase
GB8728811D0 (en) * 1987-12-09 1988-01-27 Beecham Group Plc Novel substance
US5882879A (en) * 1990-02-28 1999-03-16 Gist-Brocades, N.V. Method for influencing β-lactam antibiotic production and for isolation of large quantities of ACV synthetase

Also Published As

Publication number Publication date
BRPI0518399A2 (pt) 2008-11-18
US20080131925A1 (en) 2008-06-05
KR20070085955A (ko) 2007-08-27
WO2006061425A2 (fr) 2006-06-15
WO2006061425A3 (fr) 2006-08-03
CN101098963A (zh) 2008-01-02
EP1819813A2 (fr) 2007-08-22
MX2007006780A (es) 2007-08-06

Similar Documents

Publication Publication Date Title
SG158108A1 (en) Production of beta-lactam antibiotics by genetically modified non- naturally producing microorganisms
EP4249602A3 (fr) Procédé de préparation de bibliothèques de polynucléotides modèles
GB2446084A (en) Synthesis of four color 3-o-allyl modified photocleavable fluorescent nucleotides and related methods
MXPA05012694A (es) Metodo para la produccion de elastomeros termoplasticos expandibles.
EP2505668A3 (fr) Procédés à base de micro ARN pour le diagnostic d'un cancer du colon, du poumon, et du pancreas
SG129236A1 (en) Somatic pluripotent cells
MY156222A (en) Enzyme associated with equol synthesis
SG135146A1 (en) Melt-processable polyurethanes and a process for their production
WO2006031424A3 (fr) Souche e. coli mutante avec production accrue d'acide succinique
WO2004037988A3 (fr) Methodes de synthese de l'adn complementaire
DE602005014936D1 (en) Phosphoramidatderivate
PL1979375T3 (pl) Klastry biosyntetycznych genów kodujących lantybiotyki pochodzące od a. garbadinensis oraz a. liguriae
MXPA05008970A (es) Sistemas de revestimiento de poliuretano de un solo componente que contienen vanadio cuadrivalente.
TW200640926A (en) Pyrazolopyrimidines
TW200512223A (en) Radiation-curable resins based on ketone-aldehyde and/or urea-aldehyde resins and a process for preparing them
MX2007007387A (es) Derivados de tienopirimidina como inhibidores de fosfodiesterasa 10.
ZA200200582B (en) Genes from corynebacterium glutamicum for the biosynthesis of folic acid and their use for the microbial production of folic acid.
AU2003247279A1 (en) Furancarboxamides
GB2439039A (en) Identification of a sterol acyltransferase gene
AU2002358488A1 (en) Alleles of the glucokinase gene coryneform bacteria
WO2011040613A8 (fr) Agent thérapeutique anti-tumoral
TW200626074A (en) Fermented milk and process for producing the same
AU2003232775A1 (en) Oxathiincarboxamides
MXPA05012363A (es) Poliisocianatos bloqueados estables en la solidificacion.
TW200510535A (en) Novel vector