|
US6582908B2
(en)
|
1990-12-06 |
2003-06-24 |
Affymetrix, Inc. |
Oligonucleotides
|
|
US5308751A
(en)
|
1992-03-23 |
1994-05-03 |
General Atomics |
Method for sequencing double-stranded DNA
|
|
DK0651825T3
(en)
|
1992-07-06 |
1998-09-14 |
Harvard College |
Methods and diagnostic sets for determining the toxicity of a compound using a bacterial stress
|
|
JP2002503954A
(en)
|
1997-04-01 |
2002-02-05 |
グラクソ、グループ、リミテッド |
Nucleic acid amplification method
|
|
US6087099A
(en)
|
1997-09-08 |
2000-07-11 |
Myriad Genetics, Inc. |
Method for sequencing both strands of a double stranded DNA in a single sequencing reaction
|
|
US6232067B1
(en)
*
|
1998-08-17 |
2001-05-15 |
The Perkin-Elmer Corporation |
Adapter directed expression analysis
|
|
DE69929542T2
(en)
|
1998-10-27 |
2006-09-14 |
Affymetrix, Inc., Santa Clara |
COMPLEXITY MANAGEMENT AND ANALYSIS OF GENOMIC DNA
|
|
US6958225B2
(en)
|
1999-10-27 |
2005-10-25 |
Affymetrix, Inc. |
Complexity management of genomic DNA
|
|
WO2001040516A2
(en)
|
1999-12-02 |
2001-06-07 |
Molecular Staging Inc. |
Generation of single-strand circular dna from linear self-annealing segments
|
|
US7300751B2
(en)
|
2000-06-30 |
2007-11-27 |
Syngenta Participations Ag |
Method for identification of genetic markers
|
|
US6632611B2
(en)
|
2001-07-20 |
2003-10-14 |
Affymetrix, Inc. |
Method of target enrichment and amplification
|
|
US7297778B2
(en)
|
2001-07-25 |
2007-11-20 |
Affymetrix, Inc. |
Complexity management of genomic DNA
|
|
ES2661167T3
(en)
|
2001-10-15 |
2018-03-27 |
Bioarray Solutions Ltd. |
Multiplexed analysis of polymorphic loci by simultaneous consultation and enzyme-mediated detection
|
|
US7406385B2
(en)
|
2001-10-25 |
2008-07-29 |
Applera Corporation |
System and method for consensus-calling with per-base quality values for sample assemblies
|
|
US7459273B2
(en)
|
2002-10-04 |
2008-12-02 |
Affymetrix, Inc. |
Methods for genotyping selected polymorphism
|
|
WO2004065582A2
(en)
|
2003-01-15 |
2004-08-05 |
Dana-Farber Cancer Institute, Inc. |
Amplification of dna in a hairpin structure, and applications
|
|
WO2004081183A2
(en)
|
2003-03-07 |
2004-09-23 |
Rubicon Genomics, Inc. |
In vitro dna immortalization and whole genome amplification using libraries generated from randomly fragmented dna
|
|
JP2007524410A
(en)
|
2004-01-23 |
2007-08-30 |
リングヴィテ エーエス |
Improved polynucleotide ligation reaction
|
|
US7315019B2
(en)
|
2004-09-17 |
2008-01-01 |
Pacific Biosciences Of California, Inc. |
Arrays of optical confinements and uses thereof
|
|
US7393665B2
(en)
|
2005-02-10 |
2008-07-01 |
Population Genetics Technologies Ltd |
Methods and compositions for tagging and identifying polynucleotides
|
|
US8796441B2
(en)
|
2005-04-13 |
2014-08-05 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Human sweet and umami taste receptor variants
|
|
CN101641449B
(en)
|
2005-06-23 |
2014-01-29 |
科因股份有限公司 |
Strategies for high-throughput identification and detection of polymorphisms
|
|
US20070020640A1
(en)
|
2005-07-21 |
2007-01-25 |
Mccloskey Megan L |
Molecular encoding of nucleic acid templates for PCR and other forms of sequence analysis
|
|
AU2006295556B2
(en)
|
2005-09-29 |
2012-07-05 |
Keygene N.V. |
High throughput screening of mutagenized populations
|
|
GB0522310D0
(en)
|
2005-11-01 |
2005-12-07 |
Solexa Ltd |
Methods of preparing libraries of template polynucleotides
|
|
WO2007087312A2
(en)
|
2006-01-23 |
2007-08-02 |
Population Genetics Technologies Ltd. |
Molecular counting
|
|
US20070172839A1
(en)
|
2006-01-24 |
2007-07-26 |
Smith Douglas R |
Asymmetrical adapters and methods of use thereof
|
|
WO2007114693A2
(en)
|
2006-04-04 |
2007-10-11 |
Keygene N.V. |
High throughput detection of molecular markers based on aflp and high throughput sequencing
|
|
WO2008093098A2
(en)
|
2007-02-02 |
2008-08-07 |
Illumina Cambridge Limited |
Methods for indexing samples and sequencing multiple nucleotide templates
|
|
CA2697640C
(en)
|
2007-09-21 |
2016-06-21 |
Katholieke Universiteit Leuven |
Tools and methods for genetic tests using next generation sequencing
|
|
EP4230747A3
(en)
|
2008-03-28 |
2023-11-15 |
Pacific Biosciences Of California, Inc. |
Compositions and methods for nucleic acid sequencing
|
|
WO2009133466A2
(en)
|
2008-04-30 |
2009-11-05 |
Population Genetics Technologies Ltd. |
Asymmetric adapter library construction
|
|
US8383345B2
(en)
|
2008-09-12 |
2013-02-26 |
University Of Washington |
Sequence tag directed subassembly of short sequencing reads into long sequencing reads
|
|
US20110301042A1
(en)
|
2008-11-11 |
2011-12-08 |
Helicos Biosciences Corporation |
Methods of sample encoding for multiplex analysis of samples by single molecule sequencing
|
|
KR101797773B1
(en)
|
2009-01-30 |
2017-11-15 |
옥스포드 나노포어 테크놀로지즈 리미티드 |
Adaptors for nucleic acid constructs in transmembrane sequencing
|
|
US20100331204A1
(en)
|
2009-02-13 |
2010-12-30 |
Jeff Jeddeloh |
Methods and systems for enrichment of target genomic sequences
|
|
GB0905410D0
(en)
|
2009-03-28 |
2009-05-13 |
Gentronix Ltd |
Genotoxicity testing
|
|
US20120165202A1
(en)
|
2009-04-30 |
2012-06-28 |
Good Start Genetics, Inc. |
Methods and compositions for evaluating genetic markers
|
|
US9085798B2
(en)
|
2009-04-30 |
2015-07-21 |
Prognosys Biosciences, Inc. |
Nucleic acid constructs and methods of use
|
|
EP2248914A1
(en)
|
2009-05-05 |
2010-11-10 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
The use of class IIB restriction endonucleases in 2nd generation sequencing applications
|
|
WO2010148115A1
(en)
|
2009-06-18 |
2010-12-23 |
The Penn State Research Foundation |
Methods, systems and kits for detecting protein-nucleic acid interactions
|
|
WO2011021102A2
(en)
|
2009-08-20 |
2011-02-24 |
Population Genetics Technologies Ltd |
Compositions and methods for intramolecular nucleic acid rearrangement
|
|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
CN102933721B
(en)
|
2010-06-09 |
2015-12-02 |
凯津公司 |
Combinatorial sequence barcoding for high-throughput screening
|
|
WO2012012037A1
(en)
*
|
2010-07-19 |
2012-01-26 |
New England Biolabs, Inc. |
Oligonucleotide adaptors: compositions and methods of use
|
|
US20120244525A1
(en)
|
2010-07-19 |
2012-09-27 |
New England Biolabs, Inc. |
Oligonucleotide Adapters: Compositions and Methods of Use
|
|
CN103154273A
(en)
|
2010-09-21 |
2013-06-12 |
群体遗传学科技有限公司 |
Improving Confidence in Allele Calls with Molecular Counts
|
|
WO2012042374A2
(en)
|
2010-10-01 |
2012-04-05 |
Anssi Jussi Nikolai Taipale |
Method of determining number or concentration of molecules
|
|
EP2635679B1
(en)
|
2010-11-05 |
2017-04-19 |
Illumina, Inc. |
Linking sequence reads using paired code tags
|
|
US9074251B2
(en)
|
2011-02-10 |
2015-07-07 |
Illumina, Inc. |
Linking sequence reads using paired code tags
|
|
DK2652155T3
(en)
|
2010-12-16 |
2017-02-13 |
Gigagen Inc |
Methods for Massive Parallel Analysis of Nucleic Acids in Single Cells
|
|
US9150852B2
(en)
|
2011-02-18 |
2015-10-06 |
Raindance Technologies, Inc. |
Compositions and methods for molecular labeling
|
|
WO2012129242A2
(en)
|
2011-03-23 |
2012-09-27 |
Pacific Biosciences Of California, Inc. |
Isolation of polymerase-nucleic acid complexes and loading onto substrates
|
|
US9260753B2
(en)
|
2011-03-24 |
2016-02-16 |
President And Fellows Of Harvard College |
Single cell nucleic acid detection and analysis
|
|
CN103748236B
(en)
|
2011-04-15 |
2018-12-25 |
约翰·霍普金斯大学 |
Safe sequencing system
|
|
ES2556580T3
(en)
|
2011-07-08 |
2016-01-19 |
Keygene N.V. |
Genotyping based on sequences based on oligonucleotide ligation assays
|
|
US10767208B2
(en)
|
2011-09-06 |
2020-09-08 |
Gen-Probe Incorporated |
Closed nucleic acid structures
|
|
US9249460B2
(en)
|
2011-09-09 |
2016-02-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for obtaining a sequence
|
|
US20160153039A1
(en)
|
2012-01-26 |
2016-06-02 |
Nugen Technologies, Inc. |
Compositions and methods for targeted nucleic acid sequence enrichment and high efficiency library generation
|
|
SG10201504490QA
(en)
|
2012-01-26 |
2015-07-30 |
Nugen Technologies Inc |
Compositions And Methods For Targeted Nucleic Acid Sequence Enrichment And High Efficiency Library Generation
|
|
US9528107B2
(en)
|
2012-01-31 |
2016-12-27 |
Pacific Biosciences Of California, Inc. |
Compositions and methods for selection of nucleic acids
|
|
PT2814959T
(en)
|
2012-02-17 |
2018-04-12 |
Hutchinson Fred Cancer Res |
Compositions and methods for accurately identifying mutations
|
|
EP2820174B1
(en)
|
2012-02-27 |
2019-12-25 |
The University of North Carolina at Chapel Hill |
Methods and uses for molecular tags
|
|
EP3287531B1
(en)
|
2012-02-28 |
2019-06-19 |
Agilent Technologies, Inc. |
Method for attaching a counter sequence to a nucleic acid sample
|
|
CA2867293C
(en)
|
2012-03-13 |
2020-09-01 |
Abhijit Ajit PATEL |
Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing
|
|
ES2828661T3
(en)
|
2012-03-20 |
2021-05-27 |
Univ Washington Through Its Center For Commercialization |
Methods to Reduce the Error Rate of Parallel Massive DNA Sequencing Using Double-stranded Consensus Sequence Sequencing
|
|
US9487828B2
(en)
|
2012-05-10 |
2016-11-08 |
The General Hospital Corporation |
Methods for determining a nucleotide sequence contiguous to a known target nucleotide sequence
|
|
WO2013181170A1
(en)
|
2012-05-31 |
2013-12-05 |
Board Of Regents, The University Of Texas System |
Method for accurate sequencing of dna
|
|
DE202013012824U1
(en)
|
2012-09-04 |
2020-03-10 |
Guardant Health, Inc. |
Systems for the detection of rare mutations and a copy number variation
|
|
CN102877136B
(en)
|
2012-09-24 |
2014-03-12 |
上海交通大学 |
Genome simplification and next-generation sequencing-based deoxyribose nucleic acid (DNA) library preparation method and kit
|
|
AU2013337616B2
(en)
|
2012-11-05 |
2019-03-21 |
Gmdx Co Pty Ltd |
Methods for determining the cause of somatic mutagenesis
|
|
DK3553175T3
(en)
|
2013-03-13 |
2021-08-23 |
Illumina Inc |
PROCEDURE FOR MAKING A NUCLEIC ACID SEQUENCE LIBRARY
|
|
US10087481B2
(en)
|
2013-03-19 |
2018-10-02 |
New England Biolabs, Inc. |
Enrichment of target sequences
|
|
US11414695B2
(en)
|
2013-05-29 |
2022-08-16 |
Agilent Technologies, Inc. |
Nucleic acid enrichment using Cas9
|
|
WO2015075056A1
(en)
|
2013-11-19 |
2015-05-28 |
Thermo Fisher Scientific Baltics Uab |
Programmable enzymes for isolation of specific dna fragments
|
|
EP3771745A1
(en)
|
2013-12-28 |
2021-02-03 |
Guardant Health, Inc. |
Methods and systems for detecting genetic variants
|
|
KR102321956B1
(en)
|
2014-01-31 |
2021-11-08 |
스위프트 바이오사이언시스 인코포레이티드 |
Improved methods for processing dna substrates
|
|
US11085084B2
(en)
|
2014-09-12 |
2021-08-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
Identification and use of circulating nucleic acids
|
|
US10844428B2
(en)
*
|
2015-04-28 |
2020-11-24 |
Illumina, Inc. |
Error suppression in sequenced DNA fragments using redundant reads with unique molecular indices (UMIS)
|
|
US10465241B2
(en)
|
2015-06-15 |
2019-11-05 |
The Board Of Trustees Of The Leleand Stanford Junior University |
High resolution STR analysis using next generation sequencing
|
|
GB201515557D0
(en)
|
2015-09-02 |
2015-10-14 |
14M Genomics Ltd |
Method of sequencing
|
|
CN108350491A
(en)
|
2015-11-18 |
2018-07-31 |
加利福尼亚太平洋生物科学股份有限公司 |
Nucleic acid is loaded on base material
|
|
JP6975507B2
(en)
|
2015-12-08 |
2021-12-01 |
ツインストランド・バイオサイエンシズ・インコーポレイテッドTwinstrand Biosciences, Inc. |
Improved adapters, methods, and compositions for double-stranded sequencing
|
|
US20170283864A1
(en)
*
|
2016-03-31 |
2017-10-05 |
Agilent Technologies, Inc. |
Use of transposase and y adapters to fragment and tag dna
|
|
US11821028B2
(en)
|
2016-07-12 |
2023-11-21 |
QIAGEN Sciences, LLP |
Single end duplex DNA sequencing
|
|
WO2018031588A1
(en)
|
2016-08-09 |
2018-02-15 |
Takara Bio Usa, Inc. |
Nucleic acid adaptors with molecular identification sequences and use thereof
|
|
CN106367485B
(en)
|
2016-08-29 |
2019-04-26 |
厦门艾德生物医药科技股份有限公司 |
Double label connector groups of a kind of more positioning for detecting gene mutation and its preparation method and application
|
|
WO2018175997A1
(en)
|
2017-03-23 |
2018-09-27 |
University Of Washington |
Methods for targeted nucleic acid sequence enrichment with applications to error corrected nucleic acid sequencing
|
|
US11584958B2
(en)
|
2017-03-31 |
2023-02-21 |
Grail, Llc |
Library preparation and use thereof for sequencing based error correction and/or variant identification
|
|
SG11202003885UA
(en)
|
2017-11-08 |
2020-05-28 |
Twinstrand Biosciences Inc |
Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters
|
|
JP7420388B2
(en)
|
2018-02-13 |
2024-01-23 |
ツインストランド・バイオサイエンシズ・インコーポレイテッド |
Methods and reagents for detecting and evaluating genotoxicity
|
|
JP2021515579A
(en)
|
2018-03-15 |
2021-06-24 |
ツインストランド・バイオサイエンシズ・インコーポレイテッドTwinstrand Biosciences, Inc. |
Methods and Reagents for Concentrating Nucleic Acid Substances for Sequencing Applications and Other Nucleic Acid Substance Interrogation
|
|
WO2019183640A1
(en)
|
2018-03-23 |
2019-09-26 |
Board Of Regents, The University Of Texas System |
Efficient sequencing of dsdna with extremely low level of errors
|
|
US20210292836A1
(en)
|
2018-05-16 |
2021-09-23 |
Twinstrand Biosciences, Inc. |
Methods and reagents for resolving nucleic acid mixtures and mixed cell populations and associated applications
|
|
BR112021000409A2
(en)
|
2018-07-12 |
2021-04-06 |
Twinstrand Biosciences, Inc. |
METHODS AND REAGENTS TO CHARACTERIZE GENOMIC EDITION, CLONAL EXPANSION AND ASSOCIATED APPLICATIONS
|
|
EP4114978A4
(en)
|
2020-03-06 |
2024-07-03 |
Singular Genomics Systems, Inc. |
Linked paired strand sequencing
|