[go: up one dir, main page]

SG11201913229PA - Silk-hyaluronic acid based tissue fillers and methods of using the same - Google Patents

Silk-hyaluronic acid based tissue fillers and methods of using the same

Info

Publication number
SG11201913229PA
SG11201913229PA SG11201913229PA SG11201913229PA SG11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA
Authority
SG
Singapore
Prior art keywords
silk
methods
same
hyaluronic acid
acid based
Prior art date
Application number
SG11201913229PA
Other languages
English (en)
Inventor
Gregory H Altman
Peng Xu
Erlei Jin
Original Assignee
Evolved By Nature Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolved By Nature Inc filed Critical Evolved By Nature Inc
Publication of SG11201913229PA publication Critical patent/SG11201913229PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11201913229PA 2017-06-26 2018-06-26 Silk-hyaluronic acid based tissue fillers and methods of using the same SG11201913229PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762525131P 2017-06-26 2017-06-26
US201862641095P 2018-03-09 2018-03-09
PCT/US2018/039574 WO2019005848A1 (fr) 2017-06-26 2018-06-26 Agents de comblement tissulaire à base de soie-acide hyaluronique et leurs procédés d'utilisation

Publications (1)

Publication Number Publication Date
SG11201913229PA true SG11201913229PA (en) 2020-01-30

Family

ID=64742709

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201913229PA SG11201913229PA (en) 2017-06-26 2018-06-26 Silk-hyaluronic acid based tissue fillers and methods of using the same

Country Status (14)

Country Link
US (1) US20230338614A1 (fr)
EP (2) EP3645063B1 (fr)
JP (3) JP2020525253A (fr)
KR (1) KR20200032103A (fr)
CN (1) CN111263646A (fr)
AU (2) AU2018290810C1 (fr)
CA (1) CA3068296A1 (fr)
CO (1) CO2020000774A2 (fr)
ES (2) ES3018883T3 (fr)
IL (2) IL299584A (fr)
MA (1) MA49520A (fr)
SG (1) SG11201913229PA (fr)
UA (1) UA127350C2 (fr)
WO (1) WO2019005848A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11660372B2 (en) 2017-06-26 2023-05-30 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue fillers and methods of using the same
US12296067B2 (en) 2018-12-19 2025-05-13 Evolved By Nature, Inc. Silk-hyaluronic acid tissue fillers and methods of making and using the same

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6508431B1 (ja) 2017-09-21 2019-05-08 住友電気工業株式会社 半絶縁性ヒ化ガリウム結晶基板
WO2020205774A1 (fr) * 2019-03-29 2020-10-08 Trustees Of Tufts College Compositions à base de fibroïnes de soie, ses procédés de préparation et ses méthodes d'utilisation
BR112021024634A2 (pt) * 2019-06-06 2022-01-18 Evolved By Nature Inc Método de tratamento ou prevenção de um distúrbio, doença ou condição aliviada pela estimulação ou modulação da expressão de colágeno
CN114025971B (zh) * 2019-06-26 2023-09-15 米其林企业总公司 噪声改善胎面
CN110339398A (zh) * 2019-07-18 2019-10-18 王月玲 一种含氨基酸透明质酸钠注射剂及其制备方法
WO2021035087A1 (fr) * 2019-08-20 2021-02-25 Evolved By Nature, Inc. Compositions de soins personnels à base de soie
US20220298310A1 (en) * 2019-09-27 2022-09-22 Lg Chem, Ltd. A method of preparing polymeric microparticles, polymeric microparticles, medical composition, cosmetic composition, medical articles and cosmetic articles using the same
ES2985960T3 (es) * 2019-12-19 2024-11-07 Croma Pharma Gmbh Hialuronano modificado con tiol e hidrogel que comprende el hialuronano reticulado
KR20230119104A (ko) * 2020-06-19 2023-08-16 이발브드 바이 네이처, 인크. 조직 충진, 조직 간격화, 및 조직 벌크화를 위한 실크-히알루론산 조성물
CN116507315A (zh) * 2020-06-19 2023-07-28 自然进化公司 用于组织填充、组织间隔和组织膨胀的丝-透明质酸组合物
AU2021472120A1 (en) * 2020-09-29 2023-06-15 Ziropa, Inc. Compositions and methods for pain relief and numbing
TR202101065A1 (tr) * 2021-01-25 2022-08-22 Hacettepe Ueniversitesi Hyaluroni̇k asi̇t jel i̇çeren bi̇r doku dolgu malzemesi̇ ve üreti̇m yöntemi̇
CN114213517B (zh) * 2021-02-08 2024-07-09 复向丝泰医疗科技(苏州)有限公司 利用切向流超滤技术制备可控高浓度丝素蛋白溶液的方法
US11584784B2 (en) 2021-05-21 2023-02-21 Cambridge Crops, Inc. Systems and methods for manufacturing a silk fibroin solution and powders containing silk fibroin
WO2023275278A1 (fr) * 2021-06-30 2023-01-05 Merz Pharma Gmbh & Co. Kgaa Charges dermiques d'acide hyaluronique réticulées avec de l'éther diglycidique de glycol polyéthylénique, leur procédé de fabrication et leurs utilisations
CN113368220A (zh) * 2021-07-05 2021-09-10 云南维他源生物科技有限公司 一种ahco组合物及其制剂与应用
KR20230013682A (ko) 2021-07-16 2023-01-27 주식회사 휴메딕스 Pegde로 가교된 히알루론산 필러 및 이의 제조방법
US11864569B2 (en) 2021-08-16 2024-01-09 Cambridge Crops, Inc. Systems and methods for improving the performance of cereal using a silk fibroin solution and powders containing silk fibroin
KR102766244B1 (ko) * 2024-02-16 2025-02-10 충남대학교 산학협력단 Lc-ms/ms 기반의 히알루론산, bdde 및 bdde 가교된 히알루론산의 정량방법

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538003A (fr) 1968-03-29 1973-01-31 Anvar Procédé pour l'obtention d'articles textiles porteurs d'enzymes
FR2334107A1 (fr) 1975-12-05 1977-07-01 Pasteur Institut Procede de couplage de substances biologiques par des liaisons covalentes
US4355023A (en) 1980-09-30 1982-10-19 The Massachusetts General Hospital Antibody fragment compositions and process
US4657853A (en) 1984-09-14 1987-04-14 E. I. Du Pont De Nemours And Company Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US20060105022A1 (en) 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
US8450475B2 (en) * 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
US20110189292A1 (en) 2009-04-20 2011-08-04 Allergan, Inc. Dermal fillers comprising silk fibroin hydrogels and uses thereof
WO2011059325A2 (fr) * 2009-11-11 2011-05-19 University Of Twente, Institute For Biomedical Technology And Technical Medicine (Mira) Hydrogels à base de dextrane et d'acide hyaluronique
KR102154944B1 (ko) * 2011-06-03 2020-09-11 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
CN104105474B (zh) * 2011-09-14 2018-04-06 阿勒根公司 用于细纹治疗的真皮填充剂组合物
CN102836465B (zh) * 2012-08-30 2014-06-04 浙江星月生物科技股份有限公司 一种注射用丝素蛋白透明质酸复合凝胶及其制备与应用
WO2014055895A1 (fr) * 2012-10-05 2014-04-10 Allergan, Inc. Dispositif injectable et méthode de modelage, d'augmentation ou de correction de traits faciaux tels que du menton
US20140315828A1 (en) * 2013-04-22 2014-10-23 Allergan, Inc. Cross-linked silk-hyaluronic acid compositions
CN110003360A (zh) 2013-06-28 2019-07-12 盖尔德玛公司 用于制备交联的透明质酸产物的方法
WO2015048805A1 (fr) 2013-09-30 2015-04-02 Silk Therapeutics, Inc. Compositions à base de fragments de protéines de soie et articles manufacturés à partir de celles-ci
AU2015358537B2 (en) 2014-12-02 2021-08-19 Evolved By Nature, Inc. Silk performance apparel and products and methods of preparing the same
ES2864901T3 (es) * 2015-04-29 2021-10-14 Evolved By Nature Inc Composiciones humectantes basadas en seda y métodos de las mismas
US10175996B2 (en) 2016-05-02 2019-01-08 Norman R. Byrne Information display and control for work areas
CA3033536A1 (fr) * 2016-08-24 2018-03-01 Allergan, Inc. Hydrogels co-reticules d'acide hyaluronique-fibroine pour ameliorer la viabilite des greffes tissulaires et pour l'augmentation des tissus mous

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11660372B2 (en) 2017-06-26 2023-05-30 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue fillers and methods of using the same
US12296067B2 (en) 2018-12-19 2025-05-13 Evolved By Nature, Inc. Silk-hyaluronic acid tissue fillers and methods of making and using the same

Also Published As

Publication number Publication date
IL271692A (en) 2020-02-27
EP3645063B1 (fr) 2022-09-28
UA127350C2 (uk) 2023-07-26
JP7660619B2 (ja) 2025-04-11
CO2020000774A2 (es) 2020-05-05
IL299584A (en) 2023-03-01
JP2023139249A (ja) 2023-10-03
IL271692B2 (en) 2023-06-01
US20230338614A1 (en) 2023-10-26
ES3018883T3 (en) 2025-05-19
AU2018290810B2 (en) 2024-06-13
AU2018290810A1 (en) 2020-02-13
EP4169539C0 (fr) 2025-01-29
EP4169539B1 (fr) 2025-01-29
BR112019027687A2 (pt) 2020-09-15
KR20200032103A (ko) 2020-03-25
MA49520A (fr) 2021-04-14
CN111263646A (zh) 2020-06-09
CA3068296A1 (fr) 2019-01-03
WO2019005848A1 (fr) 2019-01-03
EP3645063A4 (fr) 2021-04-14
EP3645063A1 (fr) 2020-05-06
ES2935887T3 (es) 2023-03-13
AU2018290810C1 (en) 2024-09-12
EP4169539A1 (fr) 2023-04-26
JP2025020289A (ja) 2025-02-12
JP2020525253A (ja) 2020-08-27
AU2024219582A1 (en) 2024-10-03

Similar Documents

Publication Publication Date Title
IL271692A (en) Tissue fillers based on hyaluronic acid and silk and methods of using them
IL284082A (en) Silk-hyaluronic acid tissue fillers and methods for their preparation and use
IL268406A (en) Preparations and methods for treating hemoglobin diseases
IL260257A (en) Preparations and methods for the treatment of hemoglobinopathies
EP3474785A4 (fr) Implant vertébral et ses procédés d'utilisation
GB201513461D0 (en) Methods and devices for the production of decellularised tissue scaffolds
EP3242709A4 (fr) Stimulation cardiaque de voies auriculo-ventriculaires et/ou de tissus associés
EP3185795A4 (fr) Dispositifs et méthodes de fixation osseuse
EP3154533A4 (fr) Procédés d'anesthésie de tissu nerveux dans la voie du nerf trijumeau et utilisations médicales de ceux-ci
ZA202104969B (en) Compositions comprising 15-hepe and methods of using the same
IL275182A (en) Preparations and methods for the treatment of metabolic conditions
SG11201705450SA (en) Bacteria-comprising compositions and methods of using the same for treating and/or preventing gastrointestinal, metabolic and/or other diseases
IL272937A (en) Preparations and methods for the treatment of diseases involving fibrosis
EP3209340A4 (fr) Echafaudages de tissus microfabriqués, et leurs procédés de fabrication et d'utilisation
EP3224362A4 (fr) Compositions thérapeutiques comprenant des facteurs de transcription et leurs procédés de préparation et d'utilisation
EP3496804A4 (fr) Dispositifs bioélectriques et procédés d'utilisation
GB201709840D0 (en) Methods and medical uses
EP3282857A4 (fr) Compositions de lait humain et procédés de fabrication et d'utilisation de celles-ci
WO2019070510A9 (fr) Implant d'ostéotomie intracorporel et procédés d'utilisation
EP3229826A4 (fr) Procédés d'activation de la cicatrisation et de la réparation de tissu
EP3139850A4 (fr) Procédés et dispositifs de fixation ou de refixation d'un tissu mou à un os
MX2019010640A (es) Formas cristalinas de acido obeticolico.
EP3334730A4 (fr) Pyrrolomycines et leurs procédés d'utilisation
ZA201900984B (en) Methods and compositions for the treatment of warts
SG10201606557RA (en) Oxygen-enriched water composition, biocompatible composition comprising the same, and methods of preparing and using the same