SG11201912273WA - Charge-tagged nucleotides and methods of use thereof - Google Patents
Charge-tagged nucleotides and methods of use thereofInfo
- Publication number
- SG11201912273WA SG11201912273WA SG11201912273WA SG11201912273WA SG11201912273WA SG 11201912273W A SG11201912273W A SG 11201912273WA SG 11201912273W A SG11201912273W A SG 11201912273WA SG 11201912273W A SG11201912273W A SG 11201912273WA SG 11201912273W A SG11201912273W A SG 11201912273WA
- Authority
- SG
- Singapore
- Prior art keywords
- charge
- methods
- tagged nucleotides
- tagged
- nucleotides
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 title 1
- 125000003729 nucleotide group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/543—Immobilised enzyme(s)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/101—Modifications characterised by incorporating non-naturally occurring nucleotides, e.g. inosine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/113—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being electroactive, e.g. redox labels
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862710461P | 2018-02-16 | 2018-02-16 | |
| US201862710362P | 2018-02-16 | 2018-02-16 | |
| US201862710327P | 2018-02-16 | 2018-02-16 | |
| US201862710333P | 2018-02-16 | 2018-02-16 | |
| PCT/US2019/018565 WO2019161381A1 (fr) | 2018-02-16 | 2019-02-19 | Nucléotides marqués par une charge et leurs procédés d'utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201912273WA true SG11201912273WA (en) | 2020-01-30 |
Family
ID=67619079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201912273WA SG11201912273WA (en) | 2018-02-16 | 2019-02-19 | Charge-tagged nucleotides and methods of use thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US10851131B2 (fr) |
| EP (1) | EP3752631A4 (fr) |
| JP (2) | JP6938690B2 (fr) |
| KR (2) | KR102430323B1 (fr) |
| CN (1) | CN111164222A (fr) |
| AU (2) | AU2019221691B2 (fr) |
| BR (1) | BR112019027628A2 (fr) |
| CA (1) | CA3067433C (fr) |
| IL (1) | IL271303A (fr) |
| MX (1) | MX2019015011A (fr) |
| PH (1) | PH12019502905A1 (fr) |
| RU (1) | RU2751359C2 (fr) |
| SA (1) | SA519410901B1 (fr) |
| SG (1) | SG11201912273WA (fr) |
| WO (1) | WO2019161381A1 (fr) |
| ZA (1) | ZA201908276B (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019161381A1 (fr) | 2018-02-16 | 2019-08-22 | Illumina, Inc. | Nucléotides marqués par une charge et leurs procédés d'utilisation |
| KR102429576B1 (ko) * | 2020-04-29 | 2022-08-03 | 경희대학교 산학협력단 | 전도성 태그를 이용한 dna 염기서열을 식별하는 방법 및 장치 |
| JP2023524079A (ja) * | 2020-04-30 | 2023-06-08 | アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティー | 生体高分子の配列決定のための方法 |
| US20250109433A1 (en) * | 2023-09-22 | 2025-04-03 | Illumina, Inc. | Macromolecule blocks for nanopore sequencing |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991006678A1 (fr) | 1989-10-26 | 1991-05-16 | Sri International | Sequençage d'adn |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| US7414116B2 (en) | 2002-08-23 | 2008-08-19 | Illumina Cambridge Limited | Labelled nucleotides |
| US20090186343A1 (en) * | 2003-01-28 | 2009-07-23 | Visigen Biotechnologies, Inc. | Methods for preparing modified biomolecules, modified biomolecules and methods for using same |
| EP1725572B1 (fr) * | 2003-11-05 | 2017-05-31 | AGCT GmbH | Composes nucleotidiques macromoleculaires et leurs procedes d'utilisation |
| EP4105644A3 (fr) | 2006-03-31 | 2022-12-28 | Illumina, Inc. | Systèmes et procédés pour analyse de séquençage par synthèse |
| ES2614078T3 (es) | 2008-03-31 | 2017-05-29 | Pacific Biosciences Of California, Inc. | Generación de polimerasas modificadas para precisión mejorada en secuenciación de una única molécula |
| EP2346889B1 (fr) | 2008-09-03 | 2015-11-11 | Quantumdx Group Limited | Conception, synthese et utilisation de nucleotides synthetiques comprenant des rapporteurs ioniques |
| US20100311144A1 (en) | 2009-06-05 | 2010-12-09 | Life Technologies Corporation | Mutant dna polymerases |
| US8986930B2 (en) | 2010-07-12 | 2015-03-24 | Pacific Biosciences Of California, Inc. | Sequencing reactions with alkali metal cations for pulse width control |
| US9164053B2 (en) | 2011-09-26 | 2015-10-20 | The Regents Of The University Of California | Electronic device for monitoring single molecule dynamics |
| JP5970049B2 (ja) * | 2013-11-28 | 2016-08-17 | 日本特殊陶業株式会社 | スパークプラグおよびその製造方法 |
| CA2943952A1 (fr) * | 2014-03-24 | 2015-10-01 | The Trustees Of Columbia University In The City Of New York | Procedes chimiques pour produire des nucleotides etiquetes |
| CN107075579B (zh) * | 2014-07-15 | 2021-10-08 | 亿明达股份有限公司 | 生物化学激活的电子装置 |
| EP3294908B1 (fr) | 2015-05-12 | 2021-06-23 | Illumina, Inc. | Procédés de séquençage d'acides nucléiques |
| EP3332033B1 (fr) * | 2015-08-06 | 2021-04-21 | Pacific Biosciences of California, Inc. | Systèmes et procédés de séquençage par nanofet à molécule simple |
| US10975426B2 (en) * | 2015-09-10 | 2021-04-13 | Roche Sequencing Solutions, Inc. | Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection |
| CN108472121A (zh) * | 2015-11-20 | 2018-08-31 | 加利福尼亚太平洋生物科学股份有限公司 | 受保护的染料标记的试剂 |
| US11225687B2 (en) * | 2016-04-04 | 2022-01-18 | The Trustees Of Columbia University In The City Of New York | DNA sequencing by synthesis with nucleotide analogues and Raman detection |
| CN109072297B (zh) | 2016-04-22 | 2022-09-13 | 加利福尼亚太平洋生物科学股份有限公司 | 使用增强的核苷酸特异性三元复合物形成检测的核酸测序方法和系统 |
| US10584379B2 (en) | 2016-04-29 | 2020-03-10 | Omniome, Inc. | Method of nucleic acid sequence determination |
| US10655174B2 (en) | 2016-05-27 | 2020-05-19 | Roche Sequencing Solutions, Inc. | Tagged multi-nucleotides useful for nucleic acid sequencing |
| JP6833079B2 (ja) | 2017-08-01 | 2021-02-24 | イラミーナ インコーポレーテッド | 電界効果センサ |
| WO2019161381A1 (fr) | 2018-02-16 | 2019-08-22 | Illumina, Inc. | Nucléotides marqués par une charge et leurs procédés d'utilisation |
-
2019
- 2019-02-19 WO PCT/US2019/018565 patent/WO2019161381A1/fr not_active Ceased
- 2019-02-19 EP EP19754735.9A patent/EP3752631A4/fr not_active Withdrawn
- 2019-02-19 KR KR1020217036461A patent/KR102430323B1/ko active Active
- 2019-02-19 MX MX2019015011A patent/MX2019015011A/es unknown
- 2019-02-19 AU AU2019221691A patent/AU2019221691B2/en not_active Ceased
- 2019-02-19 RU RU2019141361A patent/RU2751359C2/ru active
- 2019-02-19 JP JP2019571441A patent/JP6938690B2/ja not_active Expired - Fee Related
- 2019-02-19 SG SG11201912273WA patent/SG11201912273WA/en unknown
- 2019-02-19 CN CN201980003313.3A patent/CN111164222A/zh active Pending
- 2019-02-19 US US16/627,035 patent/US10851131B2/en not_active Expired - Fee Related
- 2019-02-19 CA CA3067433A patent/CA3067433C/fr active Active
- 2019-02-19 BR BR112019027628-9A patent/BR112019027628A2/pt not_active IP Right Cessation
- 2019-02-19 KR KR1020197038685A patent/KR102330071B1/ko not_active Expired - Fee Related
- 2019-12-10 IL IL271303A patent/IL271303A/en unknown
- 2019-12-11 ZA ZA2019/08276A patent/ZA201908276B/en unknown
- 2019-12-20 PH PH12019502905A patent/PH12019502905A1/en unknown
- 2019-12-25 SA SA519410901A patent/SA519410901B1/ar unknown
-
2020
- 2020-11-30 US US17/106,963 patent/US11578094B2/en active Active
-
2021
- 2021-09-01 JP JP2021142695A patent/JP2022000029A/ja active Pending
-
2022
- 2022-04-12 AU AU2022202417A patent/AU2022202417A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3752631A4 (fr) | 2021-11-10 |
| US11578094B2 (en) | 2023-02-14 |
| US10851131B2 (en) | 2020-12-01 |
| ZA201908276B (en) | 2022-07-27 |
| WO2019161381A1 (fr) | 2019-08-22 |
| CN111164222A (zh) | 2020-05-15 |
| KR102430323B1 (ko) | 2022-08-08 |
| US20200123193A1 (en) | 2020-04-23 |
| RU2019141361A3 (fr) | 2021-06-15 |
| BR112019027628A2 (pt) | 2020-08-25 |
| US20210179657A1 (en) | 2021-06-17 |
| JP6938690B2 (ja) | 2021-09-22 |
| KR20210138136A (ko) | 2021-11-18 |
| CA3067433C (fr) | 2022-11-22 |
| PH12019502905A1 (en) | 2020-09-14 |
| KR102330071B1 (ko) | 2021-11-23 |
| AU2019221691A1 (en) | 2020-01-16 |
| EP3752631A1 (fr) | 2020-12-23 |
| WO2019161381A9 (fr) | 2019-11-28 |
| KR20200028344A (ko) | 2020-03-16 |
| IL271303A (en) | 2020-01-30 |
| MX2019015011A (es) | 2021-01-08 |
| SA519410901B1 (ar) | 2022-07-17 |
| RU2019141361A (ru) | 2021-06-15 |
| AU2019221691B2 (en) | 2022-04-28 |
| JP2020534790A (ja) | 2020-12-03 |
| RU2751359C2 (ru) | 2021-07-13 |
| AU2022202417A1 (en) | 2022-05-05 |
| JP2022000029A (ja) | 2022-01-04 |
| CA3067433A1 (fr) | 2019-08-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL277889A (en) | Preparations of oligonucleotides and methods of using them | |
| SG11202010131QA (en) | Oligonucleotide compositions and methods of use thereof | |
| IL271903A (en) | Combination of unnatural nucleotides and methods therefor | |
| ZA201905677B (en) | Glycan-interacting compounds and methods of use | |
| IL267291B (en) | Actonucleotidase inhibitors and methods of using them | |
| IL276687A (en) | Trialkyne coupling agents and methods of using them | |
| IL283782A (en) | Analosomes and methods of use | |
| IL274504A (en) | 2ACSS inhibitors and methods of their use | |
| IL281438A (en) | Pyridazinones and methods of using them | |
| IL289748A (en) | Heterodimers and methods of using them | |
| IL279475A (en) | Actonucleotidase inhibitors and methods of using them | |
| IL265359A (en) | Modified Oligonucleotides and Methods of Use | |
| IL283387A (en) | Diarylhydantoin compounds and methods of use thereof | |
| IL276135A (en) | Preparations and methods of use | |
| ZA202005674B (en) | Glucoamylases and methods of use thereof | |
| ZA202100780B (en) | Bismuth-thiol compositions and methods of use | |
| PL3717650T3 (pl) | Zdarzenie mon87429 kukurydzy i sposoby jego zastosowania | |
| IL276053B1 (en) | Therapeutic Gard and methods of its use | |
| ZA201908276B (en) | Charge-tagged nucleotides and methods of use thereof | |
| GB2589398B (en) | Compounds and methods of use | |
| EP3775172A4 (fr) | Oligonucléotides à permutation d'épissage et méthodes d'utilisation | |
| GB201709186D0 (en) | Construction block and methods of use | |
| HK40044292A (en) | Charge-tagged nucleotides and methods of use thereof | |
| GB201908573D0 (en) | Compounds and methods of use | |
| HK40046153A (en) | Splice-switching oligonucleotides and methods of use |