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SG11201903405UA - High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications - Google Patents

High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications

Info

Publication number
SG11201903405UA
SG11201903405UA SG11201903405UA SG11201903405UA SG11201903405UA SG 11201903405U A SG11201903405U A SG 11201903405UA SG 11201903405U A SG11201903405U A SG 11201903405UA SG 11201903405U A SG11201903405U A SG 11201903405UA SG 11201903405U A SG11201903405U A SG 11201903405UA
Authority
SG
Singapore
Prior art keywords
international
california
screening
methods
pct
Prior art date
Application number
SG11201903405UA
Inventor
Alexander Hallock
Kimberly WEMMER
Original Assignee
Gen Automation Lab Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Automation Lab Tech Inc filed Critical Gen Automation Lab Tech Inc
Publication of SG11201903405UA publication Critical patent/SG11201903405UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -,` Organization MD HIM 01E101011M 3E1 0 III11101111 100 HOE NH ill OEN International Bureau (10) International Publication Number 3 (43) International Publication Date .....••'' WO 2018/075701 Al 26 April 2018 (26.04.2018) WIP0 I PCT (51) International Patent Classification: Kimberly; 29 Fleetwood Drive, Daly City, California C12M 1/04 (2006.01) C12Q 1/00 (2006.01) 94015 (US). C12M 1/34 (2006.01) C12Q 1/68 (2018.01) (74) Agent: SUN-HOFFMAN, Lin; P.O. Box 52048, Palo Alto, (21) International Application Number: California 94303 (US). PCT/US2017/057279 (81) Designated States (unless otherwise indicated, for every (22) International Filing Date: kind of national protection available): AE, AG, AL, AM, 19 October 2017 (19.10.2017) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (25) Filing Language: English DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (26) Publication Language: English HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, (30) Priority Data: KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, 62/410,337 19 October 2016 (19.10.2016) US MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (63) Related by continuation (CON) or continuation-in-part SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (CIP) to earlier application: TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. US 15135377 (CIP) (84) Designated States (unless otherwise indicated, for every Filed on 21 April 2016 (21.04.2016) kind of regional protection available): ARIPO (BW, GH, — (71) Applicant: GENERAL AUTOMATION LAB TECH- GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, NOLOGIES, INC. [US/US]; 953 Indiana Street, Suite 372, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, San Francisco, California 94107 (US). TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, Inventors: HALLOCK, Alexander; 105 Camellia Av- (72) MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, enue, Redwood City, California 94061 (US). WEMMER, = (54) Title: HIGH RESOLUTION SYSTEMS, KITS, APPARATUS, AND METHODS FOR SCREENING MICROORGANISMS OTHER HIGH THROUGHPUT MICROBIOLOGY APPLICATIONS AND = = = = = ,-- .., -____ _ = /1117 • 0 illii _ • C:ZZz:22, 00,,,,, ologal oop l gittar • c o „,,, o 0474:7 _ --:: ,.' PoogPa ' ,';' ,Pz 112,2 7§7 27 •egrdiegeg ;.- 0 0 , 76 -811 gaboaggicti • • fapszt, ~ O poo 0 0 p0 ho sze o f = = = = _ = _ • -•, Il - ---- ,-• Il 0 N FIG. 1 11 in N © --- -- GO (57) : A microfabricated device defining a high density array of microwells is described for cultivating cells from a sample. ,-1 The device may be incubated to grow a plurality of cells, which may be split into an analysis portion and a reserve portion. Methods are 0 provided for screening a biological entity of interest using the microfabricated device, for example, for screening phosphate solubilizing \" bacteria or other bacteria producing acids. [Continued on next page] WO 2018/075701 Al MIDEDIMOM0101011EFIDINIIHIEDOEDIROIIMOVOIMIE TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — with sequence listing part of description (Rule 5.2(a))
SG11201903405UA 2016-10-19 2017-10-19 High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications SG11201903405UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662410337P 2016-10-19 2016-10-19
PCT/US2017/057279 WO2018075701A1 (en) 2016-10-19 2017-10-19 High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications

Publications (1)

Publication Number Publication Date
SG11201903405UA true SG11201903405UA (en) 2019-05-30

Family

ID=62019011

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201903405UA SG11201903405UA (en) 2016-10-19 2017-10-19 High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications

Country Status (8)

Country Link
EP (1) EP3532600A4 (en)
JP (1) JP2019535245A (en)
CN (1) CN110168069A (en)
AU (1) AU2017345402A1 (en)
CA (1) CA3041109A1 (en)
IL (1) IL266043A (en)
SG (1) SG11201903405UA (en)
WO (1) WO2018075701A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022525087A (en) * 2019-03-11 2022-05-11 ジェネラル オートメーション ラボ テクノロジーズ インコーポレイテッド How to select microbial isolates on a high density growth platform
US20210115367A1 (en) * 2019-10-18 2021-04-22 General Automation Lab Technologies Inc. Use of Resorufin for Monitoring Metabolic Activity of Cells under Anaerobic Condition
CN112813014A (en) * 2019-11-15 2021-05-18 洛阳华清天木生物科技有限公司 Strain domestication and screening method based on microfluidic technology
JP2023106932A (en) * 2022-01-21 2023-08-02 国立大学法人東北大学 Collecting device, scanning ion conductance microscope provided with the same, and collecting method
US20230279775A1 (en) * 2022-02-16 2023-09-07 Oxy Usa Inc. Using microbial dna in well planning and management
WO2024145249A1 (en) * 2022-12-28 2024-07-04 Scale Biosciences Inc. Single cell combinatorial indexing
JP2025145844A (en) * 2024-03-22 2025-10-03 Ntn株式会社 Method and device for selecting, collecting and arranging samples

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US20050070005A1 (en) * 1997-06-16 2005-03-31 Martin Keller High throughput or capillary-based screening for a bioactivity or biomolecule
US5858770A (en) * 1997-09-30 1999-01-12 Brandeis University Cell culture plate with oxygen and carbon dioxide-permeable waterproof sealing membrane
US6638730B2 (en) * 2001-03-06 2003-10-28 Council Of Scientific & Industrial Research Composition for qualitative screening of phosphate solubilizing microorganisms and a qualitative method for screening microorganisms
US7090994B2 (en) * 2001-03-07 2006-08-15 Xenogen Corporation Methods of screening for introduction of DNA into a target cell
WO2005052582A2 (en) * 2003-11-28 2005-06-09 Pamgene B.V. Methods and apparatus for cell based microarray assays
CA2685326A1 (en) * 2007-04-27 2008-11-06 Dow Global Technologies Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
WO2008157382A1 (en) * 2007-06-15 2008-12-24 Wyeth Methods for measuring ph in a small-scale cell culture system and predicting performance of cells in a large-scale culture system
US9328172B2 (en) * 2008-04-05 2016-05-03 Single Cell Technology, Inc. Method of obtaining antibodies of interest and nucleotides encoding same
JP5718221B2 (en) * 2008-05-30 2015-05-13 マサチューセッツ インスティテュート オブ テクノロジー Compositions and methods for spatial separation and screening of cells
EP2154239A1 (en) * 2008-08-14 2010-02-17 Bio-Iliberis Research and Development S.L. Microorganism capable of solubilizing phosphate and iron and its applications
CN102301002A (en) * 2008-11-12 2011-12-28 卡里斯生命科学卢森堡控股有限责任公司 Methods and systems for determining phenotypes using exosomes
WO2010085275A1 (en) * 2009-01-21 2010-07-29 Massachusetts Institute Of Technology Compositions and methods for assessing cytotoxicity of single cells
JP4674337B2 (en) * 2009-03-10 2011-04-20 国立大学法人 岡山大学 Cell observation device and cell observation method
US9234229B2 (en) * 2009-12-08 2016-01-12 The Board Of Trustees Of The Leland Stanford Junior University High throughput system for isolation, growth, and detection of lipid inclusions in bacteria
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JP2016146752A (en) * 2015-01-23 2016-08-18 株式会社イッコーズ High content analysis and generation method of three-dimensional cell cultivation model under high respiration environment for screening
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Also Published As

Publication number Publication date
EP3532600A1 (en) 2019-09-04
IL266043A (en) 2019-06-30
EP3532600A4 (en) 2020-09-16
AU2017345402A1 (en) 2019-05-23
CA3041109A1 (en) 2018-04-26
JP2019535245A (en) 2019-12-12
WO2018075701A1 (en) 2018-04-26
CN110168069A (en) 2019-08-23

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