SG11201901834WA - Micrornas as biomarkers for endometriosis - Google Patents
Micrornas as biomarkers for endometriosisInfo
- Publication number
- SG11201901834WA SG11201901834WA SG11201901834WA SG11201901834WA SG11201901834WA SG 11201901834W A SG11201901834W A SG 11201901834WA SG 11201901834W A SG11201901834W A SG 11201901834WA SG 11201901834W A SG11201901834W A SG 11201901834WA SG 11201901834W A SG11201901834W A SG 11201901834WA
- Authority
- SG
- Singapore
- Prior art keywords
- mir
- international
- pct
- endometriosis
- english
- Prior art date
Links
- 201000009273 Endometriosis Diseases 0.000 title abstract 3
- 108091070501 miRNA Proteins 0.000 title abstract 3
- 239000000090 biomarker Substances 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 108091027766 Mir-143 Proteins 0.000 abstract 1
- 108091028684 Mir-145 Proteins 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108091090860 miR-150 stem-loop Proteins 0.000 abstract 1
- 108091041042 miR-18 stem-loop Proteins 0.000 abstract 1
- 108091062221 miR-18a stem-loop Proteins 0.000 abstract 1
- 108091065175 miR-3613 stem-loop Proteins 0.000 abstract 1
- 108091032770 miR-451 stem-loop Proteins 0.000 abstract 1
- 108091030646 miR-451a stem-loop Proteins 0.000 abstract 1
- 108091040808 miR-675 stem-loop Proteins 0.000 abstract 1
- 239000002679 microRNA Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/364—Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Biophysics (AREA)
- Pregnancy & Childbirth (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1#11101111 0 11101 HOE 100011101 1110 MIN 111110111110111 OEN Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2018/044979 Al 08 March 2018 (08.03.2018) WIP0 I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 31/7105 (2006.01) G01N 33/50 (2006.01) kind of national protection available): AE, AG, AL, AM, C12Q 1/68 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (21) International Application Number: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, PCT/US2017/049284 DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, (22) International Filing Date: KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, 30 August 2017 (30.08.2017) MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (25) Filing Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (26) Publication Language: English TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: (84) Designated States (unless otherwise indicated, for every 62/381,130 30 August 2016 (30.08.2016) US kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (71) Applicant: YALE UNIVERSITY [US/US]; Two Whitney UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, Avenue, New Haven, CT 06511 (US). TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, (72) Inventor: TAYLOR, Hugh; 14 Sport Hill Road, Easton, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, CT 06612 (US). MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, — (74) Agent: SINGH, Pallab et al.; Riverside Law, LLP, Glen- KM, ML, MR, NE, SN, TD, TG). hardie Corporate Center, 1285 Drummers Lane, Suite 202, Wayne, PA 19087 (US). = (54) Title: MICRORNAS AS BIOMARKERS FOR ENDOMETRIOSIS miR-125b-. miR-150-5p miR- miR-145 = = = = miR-143 miR-500a- miR-451a miR-18a miR-675 miR-3613 _ = ce = = _ ,—, t:I ' IN ii- ii- Fold Chang . © Figure 1 00 1 -1 (57) : Disclosed herein are compositions and methods useful for the diagnosis, assessment, and characterization of endometrio- C:::: ) eqi sis in a subject in need thereof, based upon the expression level of at least one miRNA that is associated with endometriosis. C [Continued on next page] WO 2018/044979 Al MIDEDIMOMMIDIREIERNHOIRIEIMOMER Published: — with international search report (Art. 21(3)) — with sequence listing part of description (Rule 5.2(a))
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381130P | 2016-08-30 | 2016-08-30 | |
| PCT/US2017/049284 WO2018044979A1 (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201901834WA true SG11201901834WA (en) | 2019-03-28 |
Family
ID=61301726
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201901834WA SG11201901834WA (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
| SG10202102509TA SG10202102509TA (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202102509TA SG10202102509TA (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10982282B2 (en) |
| EP (1) | EP3506912B1 (en) |
| JP (2) | JP2019528081A (en) |
| KR (1) | KR20190057305A (en) |
| CN (1) | CN109890394A (en) |
| AU (1) | AU2017319325A1 (en) |
| BR (1) | BR112019004075A2 (en) |
| CA (1) | CA3035429A1 (en) |
| MX (1) | MX2019002425A (en) |
| SG (2) | SG11201901834WA (en) |
| WO (1) | WO2018044979A1 (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3122905B1 (en) | 2014-03-27 | 2020-09-09 | Yale University | Circulating micrornas as biomarkers for endometriosis |
| WO2018044979A1 (en) | 2016-08-30 | 2018-03-08 | Yale University | Micrornas as biomarkers for endometriosis |
| MX2020002216A (en) * | 2017-08-30 | 2020-08-20 | Dot Laboratories Inc | Methods and compositions for detecting and treating endometriosis. |
| EP3820483A4 (en) | 2018-07-13 | 2023-03-01 | Yale University | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ENDOMETRIOSIS |
| KR102089559B1 (en) * | 2018-08-31 | 2020-03-16 | 차의과학대학교 산학협력단 | Biomarker for diagnosing or predicting reactivity to FSH of ovary |
| EP3873487A4 (en) * | 2018-10-31 | 2022-08-03 | Yale University | QUANTITATIVE ALGORITHM FOR ENDOMETRIOSIS |
| US11315660B2 (en) | 2018-10-31 | 2022-04-26 | Dot Laboratories, Inc. | Method of detecting and treating endometriosis in a female subject |
| WO2020146544A1 (en) * | 2019-01-09 | 2020-07-16 | Research Institute At Nationwide Children's Hospital | A novel method for monitoring endometriosis and associated disorders |
| JPWO2020179895A1 (en) | 2019-03-07 | 2020-09-10 | ||
| ES2787725A1 (en) * | 2019-04-15 | 2020-10-16 | Univ Granada | METHOD OF OBTAINING USEFUL DATA TO DIAGNOSE HEREDITARY HEMORRHAGE TELANGIECTASIA |
| CN110144394A (en) * | 2019-04-18 | 2019-08-20 | 辽宁省肿瘤医院 | A kind of endometriosis diagnosis, prognostic marker and application thereof |
| EP4004554A1 (en) * | 2019-07-22 | 2022-06-01 | F. Hoffmann-La Roche AG | S100a9 as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2021013781A1 (en) * | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | Substance p as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2021013784A1 (en) * | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a8 as blood biomarker for the non-invasive diagnosis of endometriosis |
| US11965879B2 (en) | 2019-08-23 | 2024-04-23 | Mcmaster University | Method for diagnosing and assessing endometriosis |
| KR102242639B1 (en) * | 2020-01-28 | 2021-04-21 | 고려대학교 산학협력단 | Biomaker miRNA4668-5p for diagnosing liver fibrosis |
| KR102316507B1 (en) * | 2020-02-28 | 2021-10-22 | 차의과학대학교 산학협력단 | Biomarker for Ovarian reserve and use thereof |
| CN111909997B (en) * | 2020-09-09 | 2021-09-28 | 上海交通大学 | Application of miRNA marker in preparation of product for evaluating curative effect of olanzapine on schizophrenia treatment and kit |
| JP2022063860A (en) * | 2020-10-12 | 2022-04-22 | 学校法人近畿大学 | Boron compound and production method thereof |
| KR20240084586A (en) * | 2022-12-06 | 2024-06-14 | 연세대학교 산학협력단 | A composition for diagnosing endometriosis |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090317820A1 (en) | 2008-05-19 | 2009-12-24 | The Regents Of The University Of California | Micro-rna profile in human saliva and its use for detection of oral cancer |
| BRPI0921043A2 (en) | 2008-11-12 | 2018-08-07 | Caris Life Sciences Luxembourg Holdings | methods and systems for using exosomes to determine phenotypes |
| AU2010237191A1 (en) | 2009-04-07 | 2011-11-03 | Velin-Pharma A/S | Method and device for treatment of conditions associated with inflammation or undesirable activation of the immune system |
| AU2011223789A1 (en) * | 2010-03-01 | 2012-09-20 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
| JP2014513521A (en) * | 2011-01-26 | 2014-06-05 | セファイド | How to detect lung cancer |
| WO2012112883A1 (en) | 2011-02-18 | 2012-08-23 | Yale University | The kras-variant and endometriosis |
| FR2984358A1 (en) | 2011-12-16 | 2013-06-21 | Genethon | METHODS FOR THE DIAGNOSIS OF MUSCLE DYSTROPHIES |
| WO2013148151A1 (en) | 2012-03-29 | 2013-10-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Plasma microribonucleic acids as biomarkers for endometriosis and endometriosis-associated ovarian cancer |
| WO2015050875A1 (en) | 2013-10-01 | 2015-04-09 | The Regents Of The University Of California | Endometriosis classifier |
| EP3071712B1 (en) * | 2013-11-18 | 2020-06-24 | DiamiR, LLC | Methods of using mirnas from bodily fluids for detection and monitoring of parkinson's disease (pd) |
| GB201403489D0 (en) * | 2014-02-27 | 2014-04-16 | Univ London Queen Mary | Biomarkers for endometriosis |
| US9650676B2 (en) | 2014-03-19 | 2017-05-16 | University Of South Carolina | Leukocyte MicroRNAS for use in diagnosis and treatment of endometriosis |
| EP3122905B1 (en) | 2014-03-27 | 2020-09-09 | Yale University | Circulating micrornas as biomarkers for endometriosis |
| EP2924126B1 (en) * | 2014-03-28 | 2018-04-18 | Tervisetehnoloogiate Arenduskeskus AS | Method for using microRNA (miRNA) for detection of endometriosis |
| GB201603967D0 (en) * | 2016-03-08 | 2016-04-20 | Univ Birmingham | Biomarkers of traumatic brain injury |
| WO2018044979A1 (en) | 2016-08-30 | 2018-03-08 | Yale University | Micrornas as biomarkers for endometriosis |
| MX2020002216A (en) | 2017-08-30 | 2020-08-20 | Dot Laboratories Inc | Methods and compositions for detecting and treating endometriosis. |
| US11315660B2 (en) | 2018-10-31 | 2022-04-26 | Dot Laboratories, Inc. | Method of detecting and treating endometriosis in a female subject |
| EP3873487A4 (en) | 2018-10-31 | 2022-08-03 | Yale University | QUANTITATIVE ALGORITHM FOR ENDOMETRIOSIS |
| JP2022530636A (en) | 2019-04-29 | 2022-06-30 | イェール ユニバーシティー | Classifier for detection of endometriosis |
-
2017
- 2017-08-30 WO PCT/US2017/049284 patent/WO2018044979A1/en not_active Ceased
- 2017-08-30 US US16/329,436 patent/US10982282B2/en active Active
- 2017-08-30 JP JP2019511953A patent/JP2019528081A/en active Pending
- 2017-08-30 BR BR112019004075A patent/BR112019004075A2/en unknown
- 2017-08-30 SG SG11201901834WA patent/SG11201901834WA/en unknown
- 2017-08-30 CA CA3035429A patent/CA3035429A1/en active Pending
- 2017-08-30 SG SG10202102509TA patent/SG10202102509TA/en unknown
- 2017-08-30 CN CN201780066779.9A patent/CN109890394A/en active Pending
- 2017-08-30 KR KR1020197009115A patent/KR20190057305A/en not_active Ceased
- 2017-08-30 AU AU2017319325A patent/AU2017319325A1/en not_active Abandoned
- 2017-08-30 MX MX2019002425A patent/MX2019002425A/en unknown
- 2017-08-30 EP EP17847431.8A patent/EP3506912B1/en active Active
-
2021
- 2021-02-25 US US17/184,894 patent/US11220713B2/en active Active
- 2021-11-02 US US17/517,014 patent/US12077803B2/en active Active
-
2022
- 2022-09-16 JP JP2022147738A patent/JP2022188086A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR112019004075A2 (en) | 2019-05-28 |
| WO2018044979A1 (en) | 2018-03-08 |
| US20220049312A1 (en) | 2022-02-17 |
| US11220713B2 (en) | 2022-01-11 |
| JP2019528081A (en) | 2019-10-10 |
| SG10202102509TA (en) | 2021-04-29 |
| CA3035429A1 (en) | 2018-03-08 |
| EP3506912A4 (en) | 2020-08-19 |
| CN109890394A (en) | 2019-06-14 |
| MX2019002425A (en) | 2019-08-16 |
| US20210180134A1 (en) | 2021-06-17 |
| US10982282B2 (en) | 2021-04-20 |
| JP2022188086A (en) | 2022-12-20 |
| EP3506912B1 (en) | 2024-04-03 |
| US12077803B2 (en) | 2024-09-03 |
| AU2017319325A1 (en) | 2019-03-21 |
| KR20190057305A (en) | 2019-05-28 |
| EP3506912A1 (en) | 2019-07-10 |
| US20190276893A1 (en) | 2019-09-12 |
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