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SG11201811433TA - Mmp1 gene transcript for use as marker for diagnosis of ovarian cancer prognosis, and test method - Google Patents

Mmp1 gene transcript for use as marker for diagnosis of ovarian cancer prognosis, and test method

Info

Publication number
SG11201811433TA
SG11201811433TA SG11201811433TA SG11201811433TA SG11201811433TA SG 11201811433T A SG11201811433T A SG 11201811433TA SG 11201811433T A SG11201811433T A SG 11201811433TA SG 11201811433T A SG11201811433T A SG 11201811433TA SG 11201811433T A SG11201811433T A SG 11201811433TA
Authority
SG
Singapore
Prior art keywords
marker
ovarian cancer
cancer prognosis
diagnosis
prediction
Prior art date
Application number
SG11201811433TA
Inventor
Takahiro Ochiya
Akira Yokoi
Tomoyasu Kato
Original Assignee
Nat Cancer Ct
Biomimetics Sympathies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Cancer Ct, Biomimetics Sympathies Inc filed Critical Nat Cancer Ct
Publication of SG11201811433TA publication Critical patent/SG11201811433TA/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

MMP1 GENE TRANSCRIPT FOR USE AS MARKER FOR DIAGNOSIS OF OVARIAN CANCER PROGNOSIS, AND TEST METHOD 5 [Problem] To provide: a marker and a kit both for use in the prediction of ovarian cancer prognosis; and a prognosis prediction method. [Solution] A marker and a kit, both for use in the prediction of ovarian cancer prognosis, each of said marker and kit containing a transcript of matrix metalloprotease (MMP) 1gene; and a method for 10 predicting ovarian cancer prognosis using the marker or the kit, in which the expression level of matrix metalloprotease (MMP) 1 gene in a biological sample collected from a subject is by detecting an ovarian cancer prognosis prediction marker comprising a transcript of matrix metalloprotease (MMP) 1gene and then obtaining a detection value of the ovarian cancer prognosis prediction marker. 15 [Figure 1]
SG11201811433TA 2016-06-20 2017-06-20 Mmp1 gene transcript for use as marker for diagnosis of ovarian cancer prognosis, and test method SG11201811433TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016121392A JP6143920B1 (en) 2016-06-20 2016-06-20 MMP1 gene transcripts and test methods as prognostic markers for ovarian cancer
PCT/JP2017/022680 WO2017221927A1 (en) 2016-06-20 2017-06-20 Mmp1 gene transcript for use as marker for diagnosis of ovarian cancer prognosis, and test method

Publications (1)

Publication Number Publication Date
SG11201811433TA true SG11201811433TA (en) 2019-01-30

Family

ID=59012109

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201811433TA SG11201811433TA (en) 2016-06-20 2017-06-20 Mmp1 gene transcript for use as marker for diagnosis of ovarian cancer prognosis, and test method

Country Status (8)

Country Link
US (1) US20190316205A1 (en)
EP (1) EP3473729A4 (en)
JP (1) JP6143920B1 (en)
CN (1) CN110023510A (en)
AU (1) AU2017282420A1 (en)
CA (1) CA3067527A1 (en)
SG (1) SG11201811433TA (en)
WO (1) WO2017221927A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120366453A (en) * 2020-12-22 2025-07-25 复旦大学附属华山医院 Gene set for prognosis evaluation of adrenocortical carcinoma
CN114752673B (en) * 2022-04-30 2023-07-28 重庆大学附属肿瘤医院 Application of reagent for detecting ISYNA1 expression level in preparation of ovarian cancer dryness identification reagent
JPWO2024009946A1 (en) * 2022-07-08 2024-01-11
CN115966254A (en) * 2022-11-23 2023-04-14 广东药科大学 Paclitaxel drug-resistant molecular marker for epithelial ovarian cancer and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003048734A2 (en) * 2001-12-03 2003-06-12 Oncomedx, Inc. Detection of matrix metalloproteinase rna in plasma and serum
CA2828119A1 (en) * 2011-02-24 2012-08-30 Vermillion, Inc. Biomarker panels, diagnostic methods and test kits for ovarian cancer
CA2847290A1 (en) 2011-08-30 2013-03-07 Dcb-Usa Llc Gene biomarkers for prediction of susceptibility of ovarian neoplasms and/or prognosis or malignancy of ovarian cancers
AU2013331154B2 (en) * 2012-10-17 2018-02-01 Cedars-Sinai Medical Center Molecular signatures of ovarian cancer

Also Published As

Publication number Publication date
EP3473729A4 (en) 2020-02-26
JP2017225352A (en) 2017-12-28
WO2017221927A1 (en) 2017-12-28
CN110023510A (en) 2019-07-16
EP3473729A1 (en) 2019-04-24
CA3067527A1 (en) 2017-12-28
JP6143920B1 (en) 2017-06-07
US20190316205A1 (en) 2019-10-17
AU2017282420A1 (en) 2019-02-07

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