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SG11201706367WA - Systems and methods for assessing biological samples - Google Patents

Systems and methods for assessing biological samples

Info

Publication number
SG11201706367WA
SG11201706367WA SG11201706367WA SG11201706367WA SG11201706367WA SG 11201706367W A SG11201706367W A SG 11201706367WA SG 11201706367W A SG11201706367W A SG 11201706367WA SG 11201706367W A SG11201706367W A SG 11201706367WA SG 11201706367W A SG11201706367W A SG 11201706367WA
Authority
SG
Singapore
Prior art keywords
systems
methods
biological samples
assessing biological
assessing
Prior art date
Application number
SG11201706367WA
Inventor
Mingsong Chen
Kuan Moon Boo
Tiong Han Toh
Mauro Aguanno
Soo Yong Lau
Huei Steven Yeo
Wei Fuh Teo
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55404853&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201706367W(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of SG11201706367WA publication Critical patent/SG11201706367WA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0332—Cuvette constructions with temperature control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6402—Atomic fluorescence; Laser induced fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/244—Devices for focusing using image analysis techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
SG11201706367WA 2015-02-06 2016-02-05 Systems and methods for assessing biological samples SG11201706367WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562112910P 2015-02-06 2015-02-06
PCT/US2016/016886 WO2016127128A1 (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples

Publications (1)

Publication Number Publication Date
SG11201706367WA true SG11201706367WA (en) 2017-09-28

Family

ID=55404853

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10202103903UA SG10202103903UA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples
SG10201811725SA SG10201811725SA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples
SG11201706367WA SG11201706367WA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SG10202103903UA SG10202103903UA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples
SG10201811725SA SG10201811725SA (en) 2015-02-06 2016-02-05 Systems and methods for assessing biological samples

Country Status (10)

Country Link
US (4) US20160230210A1 (en)
EP (4) EP3719481B1 (en)
JP (3) JP6985144B2 (en)
KR (3) KR102494654B1 (en)
CN (2) CN113049553B (en)
BR (1) BR112017016937B1 (en)
ES (1) ES2943159T3 (en)
RU (1) RU2708542C2 (en)
SG (3) SG10202103903UA (en)
WO (1) WO2016127128A1 (en)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4480582A1 (en) 2013-01-18 2024-12-25 Biomeme, Inc. Analytic device
SG10202103903UA (en) 2015-02-06 2021-06-29 Life Technologies Corp Systems and methods for assessing biological samples
US10324041B2 (en) * 2016-12-21 2019-06-18 Abbott Japan Co., Ltd. Optical imaging system using lateral illumination for digital assays
CN106707487B (en) * 2016-12-23 2019-03-15 卡尔蔡司医疗技术股份公司 Surgical operation microscope and the device for switching it between multiple-working mode
US11047854B2 (en) 2017-02-06 2021-06-29 Abbott Japan Llc Methods for reducing noise in signal-generating digital assays
CN111356768A (en) 2017-09-15 2020-06-30 生米公司 Methods and systems for automated sample processing
CN112326652B (en) * 2017-09-20 2021-09-03 深圳市真迈生物科技有限公司 Imaging method, device and system for controlling sequence determination reaction
CN111712581A (en) * 2017-12-15 2020-09-25 生米公司 Portable device and method for analyzing samples
NL2020636B1 (en) * 2017-12-28 2019-07-08 Illumina Inc Light energy fluorescence excitation
KR102133633B1 (en) * 2018-04-17 2020-07-13 (주)로고스바이오시스템스 A device for real-time detecting nucleic acids amplification products
KR102113217B1 (en) * 2018-07-23 2020-05-21 광주과학기술원 Target protein tracing equipment using in laser inducing X-ray
CN109324024A (en) * 2018-09-17 2019-02-12 中国人民解放军陆军军医大学第三附属医院（野战外科研究所） Small integrated immunofluorescence analysis device
US10883925B2 (en) * 2018-09-24 2021-01-05 Hf Scientific, Inc. Spectrophotometer for use in explosive atmospheres
USD1016325S1 (en) 2019-01-04 2024-02-27 Meso Scale Technologies, Llc. Instrument
USD921222S1 (en) * 2019-01-04 2021-06-01 Meso Scale Technologies, Llc. Instrument
WO2020161384A1 (en) 2019-02-04 2020-08-13 Thermo Fisher Scientific Oy Method of analyzing samples, analyzing device and computer program
CA3131142A1 (en) 2019-03-21 2020-09-24 Peter EISENHOWER Multi-function analytic devices
CN110057808A (en) * 2019-05-27 2019-07-26 中国人民解放军军事科学院军事医学研究院 Sample swivel mount and Raman spectrum detector
KR102220353B1 (en) * 2019-06-10 2021-02-25 한국전자기술연구원 Fluorescence reader system measuring by time control using image sensor
KR102400907B1 (en) * 2019-06-30 2022-05-24 주식회사 진시스템 Multiplex pcr apparatus
CN110672550B (en) * 2019-09-10 2021-11-19 中国科学院上海技术物理研究所 Image spectrum analyzer for important biological resources in micro-area
CN112904013B (en) * 2019-12-04 2023-06-20 中国科学院大连化学物理研究所 A high-energy ultraviolet cross-linking instrument for biological samples
WO2021246745A1 (en) * 2020-06-03 2021-12-09 Seegene, Inc. Optical signal detection device for detecting multiple optical signals for multiple target analytes from sample
US20230304932A1 (en) 2020-07-23 2023-09-28 Life Technologies Corporation Compositions, systems and methods for biological analysis involving energy transfer dye conjugates and analytes comprising the same
KR20230054379A (en) 2020-07-23 2023-04-24 라이프 테크놀로지스 코포레이션 Systems and Methods for Biological Assays
CN112824521A (en) * 2020-07-24 2021-05-21 北京金诺美生物技术有限公司 Fluorescence excitation system, optical system and real-time fluorescence quantitative PCR instrument
US20230168198A1 (en) * 2020-08-12 2023-06-01 University Of Washington Systems and methods for imaging of real-time nucleic acid amplification tests (naats)
KR102559634B1 (en) * 2020-08-26 2023-07-26 한국전자통신연구원 Apparatus and method for pcr diagnosis based on multiwavelength light source
US12054770B2 (en) 2020-08-26 2024-08-06 Electronics And Telecommunications Research Institute Apparatus and method for PCR diagnosis based on multi-wavelength light source
KR102380565B1 (en) * 2020-09-18 2022-03-30 (주)얼라인드제네틱스 Sample inspection device for detecting fluorescence in the sample
CN116457099A (en) * 2020-09-18 2023-07-18 生米公司 Portable device and method for analyzing a sample
TWI859369B (en) * 2020-11-27 2024-10-21 緯創資通股份有限公司 Detection device and method thereof
CN113092424B (en) * 2021-03-18 2023-02-10 上海医本医疗器械有限公司 High-flux biochip analyzer
CN113122614B (en) * 2021-04-15 2021-11-16 珠海市尚维高科生物技术有限公司 Fluorescent quantitative PCR processing method and system
WO2023055340A1 (en) * 2021-09-28 2023-04-06 Hewlett-Packard Development Company, L.P. Apparatuses with immobilized capture agents in a reaction region of a chamber
CN113777768A (en) * 2021-10-13 2021-12-10 大连理工大学 Microscopic imaging and optical sensing Internet of things system based on 3D printing and manufacturing
EP4419893A4 (en) * 2021-10-20 2025-08-06 Bio Rad Laboratories Inc FLUORESCENCE DETECTION SYSTEM
KR102821812B1 (en) * 2021-11-08 2025-06-17 한국전자통신연구원 Apparatus and method for pcr diagnosis based on multiwavelength light source and orthogonal code signals
US12320747B2 (en) 2021-11-08 2025-06-03 Electronics And Telecommunications Research Institute Apparatus and method for PCR diagnosis based on multi-wavelength light source and orthogonal code signals
KR102506675B1 (en) * 2022-03-14 2023-03-08 서강대학교산학협력단 Internet of things-based portable multiplex digital polymerase chain reaction sysyem
DE102023116945B3 (en) * 2023-06-27 2024-07-11 Jenoptik Optical Systems Gmbh Multispectral light source and method

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02293651A (en) * 1989-05-08 1990-12-04 Hitachi Ltd Spectrochemical analysis of radioactive liquid
DE4013586C2 (en) * 1990-04-27 1994-08-18 Suzuki Motor Co Device for the detection of immunological agglutination
JPH05149789A (en) * 1991-11-26 1993-06-15 Sumitomo Metal Ind Ltd Raman spectroscopic measurement method and apparatus
CA2129787A1 (en) * 1993-08-27 1995-02-28 Russell G. Higuchi Monitoring multiple amplification reactions simultaneously and analyzing same
JPH07318427A (en) 1994-05-30 1995-12-08 Shimadzu Corp Fluorescence analyzer
US5932872A (en) * 1994-07-01 1999-08-03 Jeffrey H. Price Autofocus system for scanning microscopy having a volume image formation
US5672881A (en) * 1994-09-14 1997-09-30 Glyko, Inc. Charge-coupled device imaging apparatus
DE19616151A1 (en) * 1996-04-23 1997-10-30 Boehringer Mannheim Gmbh Video system for evaluating analytical test elements
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
US5754291A (en) 1996-09-19 1998-05-19 Molecular Dynamics, Inc. Micro-imaging system
JPH10170239A (en) * 1996-10-08 1998-06-26 Matsushita Electric Ind Co Ltd 3D shape measuring device
AU7103598A (en) * 1997-04-23 1998-11-13 Packard Instrument Company Inc. Measurement of fluorescence
JPH11119309A (en) 1997-10-09 1999-04-30 Minolta Co Ltd Camera
AU759974B2 (en) 1998-05-16 2003-05-01 Applied Biosystems, Llc Instrument for monitoring polymerase chain reaction of DNA
US6236456B1 (en) * 1998-08-18 2001-05-22 Molecular Devices Corporation Optical system for a scanning fluorometer
JP3761054B2 (en) 1998-10-09 2006-03-29 富士写真フイルム株式会社 Image information reader
JP3585753B2 (en) * 1998-12-15 2004-11-04 富士写真フイルム株式会社 Shooting system
DE19919092A1 (en) * 1999-04-27 2000-11-02 Zeiss Carl Jena Gmbh Arrangement for the optical evaluation of an array of objects
US20050279949A1 (en) 1999-05-17 2005-12-22 Applera Corporation Temperature control for light-emitting diode stabilization
US7387891B2 (en) * 1999-05-17 2008-06-17 Applera Corporation Optical instrument including excitation source
US7423750B2 (en) * 2001-11-29 2008-09-09 Applera Corporation Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion
DE60039062D1 (en) * 1999-11-12 2008-07-10 Du Pont FLUORIMETER WITH LIGHT SOURCE WITH LOW HEAT GENERATION
US6775567B2 (en) * 2000-02-25 2004-08-10 Xenogen Corporation Imaging apparatus
US7027932B2 (en) * 2001-03-21 2006-04-11 Olympus Optical Co., Ltd. Biochemical examination method
US7635588B2 (en) 2001-11-29 2009-12-22 Applied Biosystems, Llc Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength
JP3723145B2 (en) * 2002-03-28 2005-12-07 富士写真フイルム株式会社 Imaging apparatus, image processing apparatus, and imaging system
US9157860B2 (en) * 2002-05-16 2015-10-13 Applied Biosystems, Llc Achromatic lens array
AU2003243268A1 (en) * 2002-05-17 2003-12-02 Applera Corporation Optical instrument including excitation source
ATE537438T1 (en) * 2002-05-17 2011-12-15 Life Technologies Corp DEVICE AND METHOD FOR DISTINGUISHING SEVERAL FLUORESCENCE SIGNALS BASED ON THEIR EXCITATION WAVELENGTH
US6970240B2 (en) * 2003-03-10 2005-11-29 Applera Corporation Combination reader
US7148043B2 (en) * 2003-05-08 2006-12-12 Bio-Rad Laboratories, Inc. Systems and methods for fluorescence detection with a movable detection module
WO2004109361A1 (en) * 2003-06-02 2004-12-16 Nikon Corporation Micrroscope device
JP4474663B2 (en) 2003-08-27 2010-06-09 努 升島 Video microscope equipment
CN103884698B (en) * 2004-06-07 2017-04-12 先锋生物科技股份有限公司 Optical lens system and method for microfluidic devices
CA2588122A1 (en) * 2004-11-16 2006-05-26 Helicos Biosciences Corporation Tirf single molecule analysis and method of sequencing nucleic acids
US7417803B2 (en) * 2004-11-18 2008-08-26 Cognex Technology And Investment Corporation Focusing mechanism for a vision detector
US7324202B2 (en) * 2004-12-07 2008-01-29 Novx Systems Inc. Optical system
US7491502B2 (en) 2004-12-17 2009-02-17 The General Hospital Corporation In vivo flow cytometry system and method
US7264794B2 (en) * 2004-12-17 2007-09-04 The General Hospital Methods of in vivo cytometry
ES2285578T3 (en) 2005-01-18 2007-11-16 F. Hoffmann-La Roche Ag VISUALIZATION OF FLUORESCENCE SIGNS USING TELECENTRICITY.
WO2006092317A1 (en) * 2005-03-03 2006-09-08 Ese Embedded System Engineering Gmbh Fluorescence meter
JP4800655B2 (en) * 2005-04-01 2011-10-26 オリンパス株式会社 Light measuring device
JP2007046904A (en) * 2005-08-05 2007-02-22 Sanyo Electric Co Ltd Reaction detector
US20070037135A1 (en) * 2005-08-08 2007-02-15 Barnes Russell H System and method for the identification and quantification of a biological sample suspended in a liquid
DE102005054184B4 (en) 2005-11-14 2020-10-29 Carl Zeiss Microscopy Gmbh Multispectral lighting device and measuring method
EP1962084A1 (en) * 2007-02-21 2008-08-27 Roche Diagnostics GmbH Apparatus for emitting and detecting beams of light
DE102007020610A1 (en) 2007-04-30 2008-11-20 Thomas Dr. Ruckstuhl Container and method for detecting fluorescence
EP2225600A2 (en) * 2007-09-05 2010-09-08 Chroma Technology Corporation Light source
CN101393313B (en) * 2007-09-21 2010-06-02 鸿富锦精密工业（深圳）有限公司 color wheel
CN101419156B (en) 2007-10-23 2012-12-05 深圳迈瑞生物医疗电子股份有限公司 Spectrophotometric detecting method and apparatus , and detecting system
KR100924034B1 (en) * 2007-11-05 2009-10-27 최신규 Handheld digital microscope
US8791427B2 (en) * 2007-12-26 2014-07-29 Olympus Corporation Biological-specimen observation apparatus
JP2009254256A (en) * 2008-04-15 2009-11-05 Konica Minolta Medical & Graphic Inc Inspection apparatus
EP2148187A1 (en) * 2008-07-25 2010-01-27 Roche Diagnostics GmbH Stimulation and optical display system for fluorescence detection
JP2010142570A (en) * 2008-12-22 2010-07-01 Hoya Corp Optical system of endoscope
JP5715068B2 (en) * 2009-01-30 2015-05-07 マイクロニクス， インコーポレイテッド Portable high gain fluorescence detection system
CA2752760C (en) 2009-04-15 2019-12-24 Biocartis Sa Optical detection system for monitoring rtpcr reaction
DE202010010523U1 (en) * 2009-09-09 2010-11-18 Helixis, Inc., Carlsbad Optical system for multiple reactions
CN201622245U (en) * 2009-12-02 2010-11-03 西安工业大学 Combined testing device for laser damage threshold of thin film and optical components
JP2011158419A (en) * 2010-02-03 2011-08-18 Sony Corp Optical detector
US8436321B2 (en) 2010-05-21 2013-05-07 Li-Cor, Inc. Optical background suppression systems and methods for fluorescence imaging
JP2012022206A (en) 2010-07-15 2012-02-02 Olympus Corp Microscopic observation system
CN102243107A (en) * 2011-04-20 2011-11-16 张强 High-sensitivity up-conversion single photon detection system
CN104105957B (en) * 2011-09-30 2018-06-19 生命科技公司 For the optical system and method for bioanalysis
EP2760583B1 (en) 2011-09-30 2020-05-06 Life Technologies Corporation Systems for biological analysis
US10928321B2 (en) 2012-03-09 2021-02-23 Ubiquitome Limited Portable device for detecting molecule(s)
JP2015511015A (en) * 2012-03-16 2015-04-13 ライフ テクノロジーズ コーポレーション System and method for containing biological samples
EP2825313B1 (en) * 2012-03-16 2018-05-16 Life Technologies Corporation Systems and methods for assessing of biological samples
GB201205607D0 (en) 2012-03-29 2012-05-16 Ltd Technopath Distrib A fluorescence microtitre plate reader
WO2013146364A1 (en) * 2012-03-29 2013-10-03 三洋電機株式会社 Sample holding carrier, and fluorescence detection system and fluorescence detection device that use same
CN104143156A (en) 2013-05-06 2014-11-12 上海科斗电子科技有限公司 Intelligent entity trading system
JP6269239B2 (en) * 2013-05-28 2018-01-31 株式会社ニコン Structured illumination device and structured illumination microscope device
SG10202103903UA (en) 2015-02-06 2021-06-29 Life Technologies Corp Systems and methods for assessing biological samples

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