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SG11201705701UA - Cyclic amine derivative and pharmaceutical use thereof - Google Patents

Cyclic amine derivative and pharmaceutical use thereof

Info

Publication number
SG11201705701UA
SG11201705701UA SG11201705701UA SG11201705701UA SG11201705701UA SG 11201705701U A SG11201705701U A SG 11201705701UA SG 11201705701U A SG11201705701U A SG 11201705701UA SG 11201705701U A SG11201705701U A SG 11201705701UA SG 11201705701U A SG11201705701U A SG 11201705701UA
Authority
SG
Singapore
Prior art keywords
amine derivative
pharmaceutical use
cyclic amine
cyclic
pharmaceutical
Prior art date
Application number
SG11201705701UA
Other languages
English (en)
Inventor
Tadamasa Arai
Yasuhiro Morita
Shuji Udagawa
Katsuhiko Iseki
Naoki Izumimoto
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of SG11201705701UA publication Critical patent/SG11201705701UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11201705701UA 2015-02-27 2016-02-26 Cyclic amine derivative and pharmaceutical use thereof SG11201705701UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015038809 2015-02-27
PCT/JP2016/055814 WO2016136944A1 (fr) 2015-02-27 2016-02-26 Dérivé d'amine cyclique et utilisation pharmaceutique de celui-ci

Publications (1)

Publication Number Publication Date
SG11201705701UA true SG11201705701UA (en) 2017-08-30

Family

ID=56788746

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201705701UA SG11201705701UA (en) 2015-02-27 2016-02-26 Cyclic amine derivative and pharmaceutical use thereof

Country Status (20)

Country Link
US (1) US10173999B2 (fr)
EP (1) EP3263565B1 (fr)
JP (1) JP6569671B2 (fr)
KR (1) KR102488848B1 (fr)
CN (1) CN107250128B (fr)
AU (1) AU2016224420B2 (fr)
CA (1) CA2977614C (fr)
DK (1) DK3263565T3 (fr)
ES (1) ES2744785T3 (fr)
HU (1) HUE044722T2 (fr)
IL (1) IL253410A (fr)
MX (1) MX2017010624A (fr)
PH (1) PH12017501297B1 (fr)
PL (1) PL3263565T3 (fr)
PT (1) PT3263565T (fr)
RU (1) RU2667062C1 (fr)
SG (1) SG11201705701UA (fr)
TW (1) TWI682927B (fr)
WO (1) WO2016136944A1 (fr)
ZA (1) ZA201705293B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3275878B1 (fr) * 2015-03-24 2020-05-20 Toray Industries, Inc. Dérivé d'amine cyclique et son utilisation à des fins médicales
US10117853B2 (en) * 2015-03-24 2018-11-06 Toray Industries, Inc. Cyclic amine derivative and pharmaceutical use thereof
HUE057370T2 (hu) * 2016-08-26 2022-05-28 Toray Industries Ciklusos amin-származékok kristályai és ezek gyógyszerészeti felhasználása
MY201356A (en) 2017-03-31 2024-02-20 Toray Industries Therapeutic or prophylactic agent for peripheral neuropathies
US11510914B2 (en) 2018-03-30 2022-11-29 Toray Industries, Inc. Agent for inhibiting rise in intraneuronal calcium concentration
CA3123833A1 (fr) * 2018-12-26 2020-07-02 Toray Industries, Inc. Derive d'amine cyclique utile en tant que promoteur dela fonction advilline et nouveau derive d'amine cyclique et utilisation pharmaceutique de celui-ci
WO2021153744A1 (fr) * 2020-01-31 2021-08-05 東レ株式会社 Cristaux de dérivé d'amine cyclique et leur utilisation pharmaceutique
JPWO2021172488A1 (fr) * 2020-02-28 2021-09-02
CN111410181A (zh) * 2020-03-31 2020-07-14 福建省龙德新能源股份有限公司 一种利用醚及其衍生物回用六氟磷酸锂合成尾气中五氟化磷的方法
CN111929392B (zh) * 2020-06-18 2023-11-14 吉林医药学院 一种柱前衍生化分析n-(对甲苯磺酰基)-l-丙氨酰氯及其对映异构体的方法
CN111574437A (zh) * 2020-06-22 2020-08-25 上海长车生物科技有限公司 (e)-3-芳杂环基丙-2-烯酸衍生物及其制备和用途
CN115215803B (zh) * 2022-09-19 2022-12-30 苏州美诺医药科技有限公司 一种4-卤代-1-(二氟甲基)-1h-咪唑的制备方法
CN115260103B (zh) * 2022-09-19 2023-01-17 苏州美诺医药科技有限公司 一种4,5-二卤代-1-(二氟甲基)-1h-咪唑的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2163150B (en) 1984-07-19 1988-05-25 Sandoz Ltd 3-aminopropoxyaryl derivatives
JP2567885B2 (ja) 1987-12-15 1996-12-25 東燃化学株式会社 検体の密封方法
WO2003031432A1 (fr) 2001-10-12 2003-04-17 Novo Nordisk A/S Nouvelles piperidines substituees
DE10211770A1 (de) * 2002-03-14 2003-10-02 Boehringer Ingelheim Pharma Neue substituierte Piperidine, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US7026312B2 (en) * 2002-03-14 2006-04-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituted piperidines, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof
FR2862647B1 (fr) * 2003-11-25 2008-07-04 Aventis Pharma Sa Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant
JP2006008664A (ja) 2004-05-21 2006-01-12 Takeda Chem Ind Ltd イミダゾール誘導体、その製造法及び用途
CN102395589A (zh) * 2009-04-14 2012-03-28 安斯泰来制药株式会社 稠合吡咯并吡啶衍生物
WO2013147160A1 (fr) * 2012-03-29 2013-10-03 東レ株式会社 Dérivé d'amine cyclique et son utilisation à des fins médicales
TWI652264B (zh) * 2013-09-26 2019-03-01 東麗股份有限公司 Cyclic amine derivatives and their medical uses

Also Published As

Publication number Publication date
RU2667062C1 (ru) 2018-09-14
TWI682927B (zh) 2020-01-21
EP3263565B1 (fr) 2019-06-26
WO2016136944A1 (fr) 2016-09-01
US20180065950A1 (en) 2018-03-08
IL253410A (en) 2017-12-31
KR102488848B1 (ko) 2023-01-17
CA2977614C (fr) 2023-01-17
EP3263565A4 (fr) 2018-10-17
CN107250128B (zh) 2019-07-26
PH12017501297B1 (en) 2020-01-24
IL253410A0 (en) 2017-09-28
MX2017010624A (es) 2017-12-07
ZA201705293B (en) 2019-02-27
DK3263565T3 (da) 2019-10-07
PH12017501297A1 (en) 2018-01-29
PL3263565T3 (pl) 2019-11-29
KR20170122712A (ko) 2017-11-06
PT3263565T (pt) 2019-09-27
JPWO2016136944A1 (ja) 2017-12-07
CN107250128A (zh) 2017-10-13
AU2016224420A1 (en) 2017-08-03
BR112017017859A2 (pt) 2018-04-10
JP6569671B2 (ja) 2019-09-04
US10173999B2 (en) 2019-01-08
AU2016224420B2 (en) 2019-08-22
HUE044722T2 (hu) 2019-11-28
ES2744785T3 (es) 2020-02-26
EP3263565A1 (fr) 2018-01-03
TW201639826A (zh) 2016-11-16
CA2977614A1 (fr) 2016-09-01

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