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SG11201705606PA - Production of steviol glycosides in recombinant hosts - Google Patents

Production of steviol glycosides in recombinant hosts

Info

Publication number
SG11201705606PA
SG11201705606PA SG11201705606PA SG11201705606PA SG11201705606PA SG 11201705606P A SG11201705606P A SG 11201705606PA SG 11201705606P A SG11201705606P A SG 11201705606PA SG 11201705606P A SG11201705606P A SG 11201705606PA SG 11201705606P A SG11201705606P A SG 11201705606PA
Authority
SG
Singapore
Prior art keywords
production
steviol glycosides
recombinant hosts
hosts
recombinant
Prior art date
Application number
SG11201705606PA
Inventor
Kim Olsson
Ernesto Simon
Mikkelsen Michael Dalgaard
Simon Carlsen
Veronique Douchin
Swee Chuang Lim
Louis During
Original Assignee
Evolva Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolva Sa filed Critical Evolva Sa
Publication of SG11201705606PA publication Critical patent/SG11201705606PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/56Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/256Polyterpene radicals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P15/00Preparation of compounds containing at least three condensed carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
SG11201705606PA 2015-01-30 2016-01-29 Production of steviol glycosides in recombinant hosts SG11201705606PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562110207P 2015-01-30 2015-01-30
PCT/EP2016/052007 WO2016120486A1 (en) 2015-01-30 2016-01-29 Production of steviol glycosides in recombinant hosts

Publications (1)

Publication Number Publication Date
SG11201705606PA true SG11201705606PA (en) 2017-08-30

Family

ID=55398256

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201705606PA SG11201705606PA (en) 2015-01-30 2016-01-29 Production of steviol glycosides in recombinant hosts

Country Status (9)

Country Link
US (4) US10364450B2 (en)
EP (2) EP4148137A1 (en)
JP (1) JP2018503388A (en)
CN (1) CN108337892B (en)
AU (3) AU2016211124B2 (en)
BR (1) BR112017016338A2 (en)
CA (1) CA2973674A1 (en)
SG (1) SG11201705606PA (en)
WO (1) WO2016120486A1 (en)

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WO2017178632A1 (en) 2016-04-13 2017-10-19 Evolva Sa Production of steviol glycosides in recombinant hosts
EP3458599A1 (en) * 2016-05-16 2019-03-27 Evolva SA Production of steviol glycosides in recombinant hosts
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AU2017285444B2 (en) * 2016-06-17 2021-07-29 Cargill, Incorporated Steviol glycoside compositions for oral ingestion or use
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CN113302298B (en) 2018-11-09 2025-02-25 银杏生物制品公司 Biosynthesis of Mogroside
EP3887383A4 (en) * 2018-11-27 2022-11-09 PureCircle USA Inc. High-purity steviol glycosides
MX2021006986A (en) * 2018-12-12 2021-08-16 Conagen Inc Biosynthetic production of variant steviol glycosides.
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CA3131818A1 (en) * 2019-03-29 2020-10-08 Guohong MAO Biosynthetic production of udp-rhamnose
PH12021552730A1 (en) * 2019-05-03 2022-11-14 Amyris Inc Kaurenoic acid 13-hydroxylase (kah) variants and uses thereof
CN112080480B (en) * 2019-06-14 2023-01-03 中国科学院分子植物科学卓越创新中心 Glycosyltransferase mutants and uses thereof
CN110305855B (en) * 2019-06-26 2022-03-22 昆明理工大学 Gastrodia elata GeCPR gene and application thereof
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