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SG11201704523WA - A process for the manufacture of idalopirdine - Google Patents

A process for the manufacture of idalopirdine

Info

Publication number
SG11201704523WA
SG11201704523WA SG11201704523WA SG11201704523WA SG11201704523WA SG 11201704523W A SG11201704523W A SG 11201704523WA SG 11201704523W A SG11201704523W A SG 11201704523WA SG 11201704523W A SG11201704523W A SG 11201704523WA SG 11201704523W A SG11201704523W A SG 11201704523WA
Authority
SG
Singapore
Prior art keywords
idalopirdine
manufacture
Prior art date
Application number
SG11201704523WA
Inventor
Mikkel Fog Jacobsen
Ole Nielsen
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of SG11201704523WA publication Critical patent/SG11201704523WA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
SG11201704523WA 2014-12-12 2015-12-10 A process for the manufacture of idalopirdine SG11201704523WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK201400721 2014-12-12
PCT/EP2015/079209 WO2016091997A1 (en) 2014-12-12 2015-12-10 A process for the manufacture of idalopirdine

Publications (1)

Publication Number Publication Date
SG11201704523WA true SG11201704523WA (en) 2017-07-28

Family

ID=55077474

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201704523WA SG11201704523WA (en) 2014-12-12 2015-12-10 A process for the manufacture of idalopirdine

Country Status (5)

Country Link
US (1) US20160168089A1 (en)
AR (1) AR102980A1 (en)
SG (1) SG11201704523WA (en)
TW (1) TW201630881A (en)
WO (1) WO2016091997A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS60352B1 (en) 2014-12-12 2020-07-31 Japan Tobacco Inc Dihydropyrimidine-2-one compounds and medicinal uses thereof
WO2017174691A1 (en) 2016-04-08 2017-10-12 H. Lundbeck A/S A process for the manufacture of idalopirdine via hydrogenation of an imine
WO2018013686A1 (en) * 2016-07-12 2018-01-18 Concert Pharmaceuticals, Inc. Deuterated idalopirdine
JP7282546B2 (en) 2018-02-28 2023-05-29 日本たばこ産業株式会社 4-methyldihydropyrimidinone compound and pharmaceutical use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042685A (en) * 1962-07-03 Process of making g-fluoro tryptamine
EP0807631B1 (en) * 1996-05-15 2003-03-12 Sankyo Company Limited Tricyclic compounds having fungicidal activity, their preparation and their use
PT1859798E (en) 2001-03-29 2016-03-31 Lilly Co Eli N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor
US7022645B2 (en) * 2003-08-04 2006-04-04 Catalytic Distillation Technologies Ni hydrogenation catalysts, manufacture and use
AR065804A1 (en) * 2007-03-23 2009-07-01 Smithkline Beecham Corp COMPOSITE OF INDOL CARBOXAMIDE, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS IT AND USE OF THIS COMPOUND TO PREPARE A MEDICINAL PRODUCT
JP5373764B2 (en) * 2007-04-16 2013-12-18 マリンクロッド エルエルシー Novel opiate reduction using catalytic hydrogen transfer reaction
TW201139370A (en) 2009-12-23 2011-11-16 Lundbeck & Co As H Processes for the manufacture of a pharmaceutically active agent

Also Published As

Publication number Publication date
AR102980A1 (en) 2017-04-05
TW201630881A (en) 2016-09-01
WO2016091997A1 (en) 2016-06-16
US20160168089A1 (en) 2016-06-16

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