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SG11201703152RA - Reducing viscosity of pharmaceutical formulations - Google Patents

Reducing viscosity of pharmaceutical formulations

Info

Publication number
SG11201703152RA
SG11201703152RA SG11201703152RA SG11201703152RA SG11201703152RA SG 11201703152R A SG11201703152R A SG 11201703152RA SG 11201703152R A SG11201703152R A SG 11201703152RA SG 11201703152R A SG11201703152R A SG 11201703152RA SG 11201703152R A SG11201703152R A SG 11201703152RA
Authority
SG
Singapore
Prior art keywords
pharmaceutical formulations
reducing viscosity
viscosity
reducing
formulations
Prior art date
Application number
SG11201703152RA
Inventor
Christopher James Sloey
Sekhar Kanapuram
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54427875&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201703152R(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG11201703152RA publication Critical patent/SG11201703152RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201703152RA 2014-10-23 2015-10-22 Reducing viscosity of pharmaceutical formulations SG11201703152RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462067637P 2014-10-23 2014-10-23
PCT/US2015/056972 WO2016065181A1 (en) 2014-10-23 2015-10-22 Reducing viscosity of pharmaceutical formulations

Publications (1)

Publication Number Publication Date
SG11201703152RA true SG11201703152RA (en) 2017-05-30

Family

ID=54427875

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201703152RA SG11201703152RA (en) 2014-10-23 2015-10-22 Reducing viscosity of pharmaceutical formulations

Country Status (17)

Country Link
US (3) US11813328B2 (en)
EP (2) EP3209332B1 (en)
JP (3) JP2017531682A (en)
KR (1) KR102534017B1 (en)
CN (2) CN114569716A (en)
AU (2) AU2015335743B2 (en)
BR (1) BR112017008125B1 (en)
CA (1) CA2964786C (en)
CL (2) CL2017000984A1 (en)
EA (3) EA202191513A1 (en)
ES (1) ES2964713T3 (en)
IL (2) IL287947B2 (en)
MA (1) MA54716A (en)
MX (2) MX388858B (en)
SG (1) SG11201703152RA (en)
WO (1) WO2016065181A1 (en)
ZA (1) ZA201702762B (en)

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US12257343B2 (en) 2017-04-28 2025-03-25 Amgen Inc. Excipients to reduce the viscosity of antibody formulations and formulation compositions
US12103979B2 (en) * 2017-04-28 2024-10-01 Amgen Inc. N-acetylated and non-acetylated dipeptides containing arginine to reduce the viscosity of viscous compositions of therapeutic polypeptides
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JP6577683B2 (en) * 2017-09-22 2019-09-18 旭化成ファーマ株式会社 Liquid pharmaceutical composition containing teriparatide having excellent stability
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WO2022217021A1 (en) * 2021-04-09 2022-10-13 Avantor Performance Materials, Llc Performance-enhancing excipients and methods of reducing viscosity and increasing stability of biologic formulations
WO2025175164A1 (en) * 2024-02-16 2025-08-21 Regeneron Pharmaceuticals, Inc. Methods of producing concentrated formulated drug substances comprising proteins, and concentrated formulated drug substance made by the methods

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Also Published As

Publication number Publication date
CL2019002190A1 (en) 2019-11-22
JP2017531682A (en) 2017-10-26
EA201790787A1 (en) 2017-08-31
IL251726B (en) 2021-12-01
JP6965321B2 (en) 2021-11-10
AU2015335743B2 (en) 2020-12-24
ZA201702762B (en) 2022-12-21
CA2964786A1 (en) 2016-04-28
AU2015335743A1 (en) 2017-05-04
US20250345421A1 (en) 2025-11-13
JP7411615B2 (en) 2024-01-11
EA033444B1 (en) 2019-10-31
EP3909611B1 (en) 2023-08-30
CN107206070A (en) 2017-09-26
US20170333559A1 (en) 2017-11-23
CA2964786C (en) 2023-10-17
MA54716A (en) 2021-11-17
MX2021015789A (en) 2022-01-27
AU2021200990A1 (en) 2021-03-11
EA038462B1 (en) 2021-08-31
CL2017000984A1 (en) 2018-01-05
EA202191513A1 (en) 2021-11-30
EP3209332A1 (en) 2017-08-30
KR102534017B1 (en) 2023-05-19
US20240066124A1 (en) 2024-02-29
JP2022009223A (en) 2022-01-14
US12318447B2 (en) 2025-06-03
BR112017008125B1 (en) 2023-11-21
ES2964713T3 (en) 2024-04-09
IL287947A (en) 2022-01-01
WO2016065181A1 (en) 2016-04-28
US11813328B2 (en) 2023-11-14
CN107206070B (en) 2022-01-18
MX388858B (en) 2025-03-20
MX2017005243A (en) 2017-08-18
IL287947B2 (en) 2024-08-01
IL251726A0 (en) 2017-06-29
IL287947B1 (en) 2024-04-01
KR20170071518A (en) 2017-06-23
CN114569716A (en) 2022-06-03
AU2021200990B2 (en) 2023-02-16
EA201991447A1 (en) 2019-11-29
JP2020037559A (en) 2020-03-12
BR112017008125A2 (en) 2018-06-19
EP3909611A1 (en) 2021-11-17
EP3209332B1 (en) 2021-05-26

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