SG11201703403TA - Anti-tim-3 antibodies - Google Patents
Anti-tim-3 antibodiesInfo
- Publication number
- SG11201703403TA SG11201703403TA SG11201703403TA SG11201703403TA SG11201703403TA SG 11201703403T A SG11201703403T A SG 11201703403TA SG 11201703403T A SG11201703403T A SG 11201703403TA SG 11201703403T A SG11201703403T A SG 11201703403TA SG 11201703403T A SG11201703403T A SG 11201703403TA
- Authority
- SG
- Singapore
- Prior art keywords
- tim
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/7051—T-cell receptor (TcR)-CD3 complex
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201419089A GB201419089D0 (en) | 2014-10-27 | 2014-10-27 | Anti-TIM-3 antibodies |
| GB201419092A GB201419092D0 (en) | 2014-10-27 | 2014-10-27 | Anti-TIM-3 antibodies |
| PCT/SG2015/050415 WO2016068803A1 (en) | 2014-10-27 | 2015-10-27 | Anti-tim-3 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201703403TA true SG11201703403TA (en) | 2017-05-30 |
Family
ID=55857945
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201803042PA SG10201803042PA (en) | 2014-10-27 | 2015-10-27 | Anti-tim-3 antibodies |
| SG11201703403TA SG11201703403TA (en) | 2014-10-27 | 2015-10-27 | Anti-tim-3 antibodies |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201803042PA SG10201803042PA (en) | 2014-10-27 | 2015-10-27 | Anti-tim-3 antibodies |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10259874B2 (en) |
| EP (1) | EP3212231B1 (en) |
| JP (1) | JP6709215B2 (en) |
| KR (1) | KR20170075778A (en) |
| CN (2) | CN110294807B (en) |
| AU (1) | AU2015340056A1 (en) |
| CA (1) | CA2965960A1 (en) |
| SG (2) | SG10201803042PA (en) |
| WO (1) | WO2016068803A1 (en) |
Families Citing this family (63)
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|---|---|---|---|---|
| GB201419094D0 (en) * | 2014-10-27 | 2014-12-10 | Agency Science Tech & Res | Anti-TIM-3-antibodies |
| US10259874B2 (en) | 2014-10-27 | 2019-04-16 | Agency For Science, Technology And Research | Anti-TIM-3 antibodies |
| CA2978892A1 (en) | 2015-03-06 | 2016-09-15 | Sorrento Therapeutics, Inc. | Antibody therapeutics that bind tim3 |
| WO2017031242A1 (en) * | 2015-08-20 | 2017-02-23 | Sutro Biopharma, Inc. | Anti-tim-3 antibodies, compositions comprising anti-tim-3 antibodies and methods of making and using anti-tim-3 antibodies |
| KR20230091191A (en) * | 2016-05-27 | 2023-06-22 | 아게누스 인코포레이티드 | Anti-tim-3 antibodies and methods of use thereof |
| WO2017220989A1 (en) | 2016-06-20 | 2017-12-28 | Kymab Limited | Anti-pd-l1 and il-2 cytokines |
| SG10201911972QA (en) | 2016-07-14 | 2020-02-27 | Bristol Myers Squibb Co | Antibodies against tim3 and uses thereof |
| JOP20190013A1 (en) * | 2016-08-25 | 2019-01-31 | Lilly Co Eli | Anti-tim-3 antibodies |
| EP3970749A1 (en) * | 2016-08-26 | 2022-03-23 | BeiGene, Ltd. | Anti-tim-3 antibodies and use thereof |
| AU2017345759B2 (en) | 2016-10-21 | 2024-06-20 | Adimab, Llc | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
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| EP3565598A4 (en) * | 2017-01-03 | 2020-10-28 | Trellis Bioscience, LLC | NATIVE HUMAN ANTIBODIES FOR IMMUNCHECKPOINT MODULATION TARGETS TIM-3 AND B7-H3 |
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| CN111886255B (en) | 2018-01-12 | 2025-04-04 | 百时美施贵宝公司 | Anti-TIM3 antibodies and uses thereof |
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| CN110272489B (en) * | 2018-03-15 | 2023-08-22 | 上海健信生物医药科技有限公司 | A fully humanized antibody molecule against TIM-3, an antigen-binding fragment and its medical application |
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| CN102492038B (en) * | 2011-12-09 | 2014-05-28 | 中国人民解放军军事医学科学院基础医学研究所 | Anti-human Tim-3 neutralized monoclonal antibody L3D and application thereof |
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| US10259874B2 (en) | 2014-10-27 | 2019-04-16 | Agency For Science, Technology And Research | Anti-TIM-3 antibodies |
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-
2015
- 2015-10-27 US US15/521,685 patent/US10259874B2/en active Active
- 2015-10-27 JP JP2017522640A patent/JP6709215B2/en active Active
- 2015-10-27 SG SG10201803042PA patent/SG10201803042PA/en unknown
- 2015-10-27 CN CN201910641759.0A patent/CN110294807B/en active Active
- 2015-10-27 CA CA2965960A patent/CA2965960A1/en not_active Abandoned
- 2015-10-27 EP EP15855010.3A patent/EP3212231B1/en active Active
- 2015-10-27 SG SG11201703403TA patent/SG11201703403TA/en unknown
- 2015-10-27 KR KR1020177014444A patent/KR20170075778A/en not_active Withdrawn
- 2015-10-27 AU AU2015340056A patent/AU2015340056A1/en not_active Abandoned
- 2015-10-27 WO PCT/SG2015/050415 patent/WO2016068803A1/en not_active Ceased
- 2015-10-27 CN CN201580071169.9A patent/CN107405397B/en active Active
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2019
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Also Published As
| Publication number | Publication date |
|---|---|
| US20170240633A1 (en) | 2017-08-24 |
| US11142574B2 (en) | 2021-10-12 |
| KR20170075778A (en) | 2017-07-03 |
| EP3212231A1 (en) | 2017-09-06 |
| JP6709215B2 (en) | 2020-06-10 |
| CA2965960A1 (en) | 2016-05-06 |
| EP3212231B1 (en) | 2021-04-28 |
| CN110294807A (en) | 2019-10-01 |
| SG10201803042PA (en) | 2018-06-28 |
| CN107405397B (en) | 2020-08-25 |
| CN110294807B (en) | 2023-05-12 |
| AU2015340056A1 (en) | 2017-05-25 |
| WO2016068803A1 (en) | 2016-05-06 |
| US10259874B2 (en) | 2019-04-16 |
| US20190185564A1 (en) | 2019-06-20 |
| JP2017536111A (en) | 2017-12-07 |
| EP3212231A4 (en) | 2018-03-28 |
| CN107405397A (en) | 2017-11-28 |
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