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SG11201701870PA - Injectable microparticles for hyper-localized release of therapeutic agents - Google Patents

Injectable microparticles for hyper-localized release of therapeutic agents

Info

Publication number
SG11201701870PA
SG11201701870PA SG11201701870PA SG11201701870PA SG11201701870PA SG 11201701870P A SG11201701870P A SG 11201701870PA SG 11201701870P A SG11201701870P A SG 11201701870PA SG 11201701870P A SG11201701870P A SG 11201701870PA SG 11201701870P A SG11201701870P A SG 11201701870PA
Authority
SG
Singapore
Prior art keywords
hyper
therapeutic agents
localized release
injectable microparticles
microparticles
Prior art date
Application number
SG11201701870PA
Inventor
James A Helliwell
Amanda M Malone
Original Assignee
Eupraxia Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eupraxia Pharmaceuticals Inc filed Critical Eupraxia Pharmaceuticals Inc
Publication of SG11201701870PA publication Critical patent/SG11201701870PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
SG11201701870PA 2014-09-19 2015-09-18 Injectable microparticles for hyper-localized release of therapeutic agents SG11201701870PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462052959P 2014-09-19 2014-09-19
PCT/US2015/051072 WO2016044799A1 (en) 2014-09-19 2015-09-18 Injectable microparticles for hyper-localized release of therapeutic agents

Publications (1)

Publication Number Publication Date
SG11201701870PA true SG11201701870PA (en) 2017-04-27

Family

ID=55533935

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201902407PA SG10201902407PA (en) 2014-09-19 2015-09-18 Injectable microparticles for hyper-localized release of therapeutic agents
SG11201701870PA SG11201701870PA (en) 2014-09-19 2015-09-18 Injectable microparticles for hyper-localized release of therapeutic agents

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201902407PA SG10201902407PA (en) 2014-09-19 2015-09-18 Injectable microparticles for hyper-localized release of therapeutic agents

Country Status (14)

Country Link
US (1) US20170246117A1 (en)
EP (1) EP3193847A4 (en)
JP (1) JP2017528527A (en)
KR (1) KR20170056573A (en)
CN (1) CN107106506A (en)
AU (1) AU2015317339A1 (en)
BR (1) BR112017005666A2 (en)
CA (1) CA2960860A1 (en)
CL (1) CL2017000664A1 (en)
IL (1) IL251216A0 (en)
MX (1) MX2017003638A (en)
RU (1) RU2017113354A (en)
SG (2) SG10201902407PA (en)
WO (1) WO2016044799A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201604814WA (en) 2013-03-21 2016-08-30 Eupraxia Pharmaceuticals USA LLC Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
PT3206672T (en) 2015-10-27 2018-06-20 Eupraxia Pharmaceuticals Inc FORMULATIONS OF PROLONGED RELEASE OF LOCAL ANESTHETICS
JP2020536955A (en) 2017-10-06 2020-12-17 ファウンドリー セラピューティクス, インコーポレイテッド Implantable depot for controlled release of therapeutic agent
CN111655303A (en) 2018-01-08 2020-09-11 铸造疗法股份有限公司 Devices, systems and methods for treating intraluminal cancer via controlled delivery of therapeutic agents
CN112367980A (en) 2018-05-12 2021-02-12 铸造疗法股份有限公司 Implantable reservoir for controlled release of therapeutic agents
MX2020012458A (en) 2018-05-24 2021-04-28 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound.
US11689849B2 (en) 2018-05-24 2023-06-27 Nureva, Inc. Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones
US11690806B2 (en) 2018-05-24 2023-07-04 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
CN112867484A (en) 2018-08-28 2021-05-28 铸造疗法股份有限公司 Polymeric implants
JP7547364B2 (en) * 2019-04-10 2024-09-09 ユープラシア ファーマシューティカルズ インク. Process for Producing Drug Crystals of Desired Particle Size Distribution and Morphology
WO2022231930A1 (en) 2021-04-26 2022-11-03 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
WO2025006497A1 (en) * 2023-06-26 2025-01-02 Eupraxia Pharmaceuticals Inc. Long-acting intra-articular dosage forms containing fluticasone propionate and use thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
GB0027357D0 (en) * 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
WO2002058670A1 (en) * 2001-01-25 2002-08-01 Euroceltique S.A. Local anesthetic, and method of use
CA2510320C (en) * 2002-12-20 2012-10-09 St. James Associates Llc/Faber Research Series Coated particles for sustained-release pharmaceutical administration
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
CA2533406C (en) * 2003-07-31 2013-01-22 Sol-Gel Technologies Ltd. Microcapsules loaded with active ingredients and a method for their preparation
WO2009001697A2 (en) * 2007-06-25 2008-12-31 Otsuka Pharmaceutical Co., Ltd. Microspheres having core/shell structure
US8846068B2 (en) * 2008-04-18 2014-09-30 Warsaw Orthopedic, Inc. Methods and compositions for treating post-operative pain comprising a local anesthetic
KR101423237B1 (en) * 2010-05-04 2014-07-30 주식회사 삼양바이오팜 Release controlled pharmaceutical composition comprising tamsulosin or pharmaceutically acceptable salts thereof, and oral dosage form comprising the composition
JP5222917B2 (en) * 2010-09-21 2013-06-26 財團法人工業技術研究院 Sustained release composition and method for producing the same
CN102070895B (en) * 2010-11-17 2013-03-27 无锡中科光远生物材料有限公司 Core-shell microcapsule and preparation method thereof
JP6083936B2 (en) * 2011-03-11 2017-02-22 大阪ガスケミカル株式会社 Method for producing sustained release particles
CA2853965A1 (en) * 2011-11-03 2013-05-10 Gtx, Inc. Pharmaceutical compositions of selective androgen receptor modulators and methods of use thereof
US20150044271A1 (en) * 2012-02-27 2015-02-12 O-Ray Pharma, Inc. Solid drug implants for intracochlear delivery of therapeutics for the treatment of otic disorders
SG10201604814WA (en) * 2013-03-21 2016-08-30 Eupraxia Pharmaceuticals USA LLC Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith

Also Published As

Publication number Publication date
EP3193847A4 (en) 2018-06-06
RU2017113354A (en) 2018-10-19
SG10201902407PA (en) 2019-04-29
RU2017113354A3 (en) 2019-04-18
AU2015317339A1 (en) 2017-04-27
BR112017005666A2 (en) 2017-12-19
WO2016044799A1 (en) 2016-03-24
JP2017528527A (en) 2017-09-28
CA2960860A1 (en) 2016-03-24
MX2017003638A (en) 2017-11-08
CN107106506A (en) 2017-08-29
KR20170056573A (en) 2017-05-23
US20170246117A1 (en) 2017-08-31
EP3193847A1 (en) 2017-07-26
IL251216A0 (en) 2017-05-29
CL2017000664A1 (en) 2018-03-02

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