SG11201701455SA - Cytotoxic benzodiazepine derivatives - Google Patents

Cytotoxic benzodiazepine derivatives

Info

Publication number: SG11201701455SA
Authority: SG; Singapore
Prior art keywords: benzodiazepine derivatives; cytotoxic benzodiazepine; cytotoxic; derivatives; benzodiazepine
Prior art date: 2014-09-03

Application number

SG11201701455SA

Inventor

Ravi V J Chari

Michael Louis Miller

Manami Shizuka

Original Assignee

Immunogen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-09-03

Filing date

2015-09-02

Publication date

2017-03-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54140691&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201701455S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2015-09-02 Application filed by Immunogen Inc filed Critical Immunogen Inc

2017-03-30 Publication of SG11201701455SA publication Critical patent/SG11201701455SA/en

Classifications

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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
- C—CHEMISTRY; METALLURGY
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- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Physical Education & Sports Medicine (AREA)
Neurology (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Oncology (AREA)
Crystallography & Structural Chemistry (AREA)
Urology & Nephrology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Reproductive Health (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Virology (AREA)

SG11201701455SA 2014-09-03 2015-09-02 Cytotoxic benzodiazepine derivatives SG11201701455SA (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US201462045248P	2014-09-03	2014-09-03
US201462087040P	2014-12-03	2014-12-03
US201562149370P	2015-04-17	2015-04-17
US201562164305P	2015-05-20	2015-05-20
PCT/US2015/048059 WO2016036801A1 (en)	2014-09-03	2015-09-02	Cytotoxic benzodiazepine derivatives

Publications (1)

Publication Number	Publication Date
SG11201701455SA true SG11201701455SA (en)	2017-03-30

Family

ID=54140691

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SG11201701455SA SG11201701455SA (en)	2014-09-03	2015-09-02	Cytotoxic benzodiazepine derivatives
SG10201901824UA SG10201901824UA (en)	2014-09-03	2015-09-02	Cytotoxic benzodiazepine derivatives

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SG10201901824UA SG10201901824UA (en)	2014-09-03	2015-09-02	Cytotoxic benzodiazepine derivatives

Country Status (33)

Country	Link
US (5)	US9669102B2 (en)
EP (2)	EP3189056B1 (en)
JP (4)	JP6606545B2 (en)
KR (2)	KR20240023671A (en)
CN (2)	CN116514903A (en)
AU (3)	AU2015311987B2 (en)
BR (1)	BR112017002963A2 (en)
CA (1)	CA2959630A1 (en)
CL (1)	CL2017000507A1 (en)
CO (1)	CO2017003011A2 (en)
CR (1)	CR20170111A (en)
CY (1)	CY1123325T1 (en)
DK (1)	DK3189056T3 (en)
DO (1)	DOP2017000053A (en)
EA (1)	EA034138B1 (en)
EC (1)	ECSP17020133A (en)
ES (1)	ES2815353T3 (en)
HU (1)	HUE051002T2 (en)
IL (4)	IL250712B (en)
LT (1)	LT3189056T (en)
MA (1)	MA54254A (en)
MX (1)	MX2017002758A (en)
PE (1)	PE20170775A1 (en)
PH (1)	PH12017500358A1 (en)
PL (1)	PL3189056T3 (en)
PT (1)	PT3189056T (en)
RS (1)	RS60751B1 (en)
SG (2)	SG11201701455SA (en)
SI (1)	SI3189056T1 (en)
SM (1)	SMT202000449T1 (en)
TN (1)	TN2017000070A1 (en)
TW (4)	TWI697493B (en)
WO (1)	WO2016036801A1 (en)

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WO2018183494A1 (en)	2017-03-31	2018-10-04	Immunogen, Inc.	Cd19-targeting antibody-drug conjugates
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TWI897855B (en)	2018-10-26	2025-09-21	美商免疫遺傳股份有限公司	Epcam antibodies, activatable antibodies, and immunoconjugates, and uses thereof
AU2020240310A1 (en) *	2019-03-21	2021-10-07	Immunogen, Inc.	Methods of preparing cell-binding agent-drug conjugates
CN113631191B (en) *	2019-03-27	2024-09-27	第一三共株式会社	Combination of antibody-pyrrolobenzodiazepine derivative conjugate and PARP inhibitor
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AU2023298568A1 (en)	2022-06-30	2025-01-09	Toray Industries, Inc.	Pharmaceutical composition for cancer treatment and/or prevention
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IL250712B (en)	2020-04-30
DOP2017000053A (en)	2017-05-31
PH12017500358A1 (en)	2017-07-17
IL281317B (en)	2022-04-01
AU2015311987B2 (en)	2020-06-04
AU2020227006B2 (en)	2022-05-12
SMT202000449T1 (en)	2020-09-10
RS60751B1 (en)	2020-10-30
TW202417447A (en)	2024-05-01
US11116845B2 (en)	2021-09-14
US10238751B2 (en)	2019-03-26
IL291598A (en)	2022-05-01
TW202037596A (en)	2020-10-16
JP7132311B2 (en)	2022-09-06
EP3189056B1 (en)	2020-06-10
KR20240023671A (en)	2024-02-22
EP3189056A1 (en)	2017-07-12
CL2017000507A1 (en)	2017-11-03
MA54254A (en)	2021-09-22
JP2017527563A (en)	2017-09-21
US20160082114A1 (en)	2016-03-24
CY1123325T1 (en)	2021-12-31
WO2016036801A1 (en)	2016-03-10
IL250712A0 (en)	2017-08-31
KR102632830B1 (en)	2024-02-02
US10722588B2 (en)	2020-07-28
EA034138B1 (en)	2020-01-09
AU2022202418B2 (en)	2024-06-06
PE20170775A1 (en)	2017-07-04
CR20170111A (en)	2017-05-23
ES2815353T3 (en)	2021-03-29
JP2021042234A (en)	2021-03-18
JP6802340B2 (en)	2020-12-16
MX2017002758A (en)	2017-10-20
PL3189056T3 (en)	2020-11-02
AU2015311987A1 (en)	2017-03-09
US20170340748A1 (en)	2017-11-30
JP2022166293A (en)	2022-11-01
TN2017000070A1 (en)	2018-07-04
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TWI697493B (en)	2020-07-01
US20230233697A1 (en)	2023-07-27
AU2020227006A1 (en)	2020-09-24
PT3189056T (en)	2020-09-04
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BR112017002963A2 (en)	2019-07-16
CA2959630A1 (en)	2016-03-10
ECSP17020133A (en)	2018-02-28
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EP3778601A1 (en)	2021-02-17
CN106604927B (en)	2022-08-09
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SG10201901824UA (en)	2019-03-28
SI3189056T1 (en)	2020-10-30
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JP6606545B2 (en)	2019-11-13
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US9669102B2 (en)	2017-06-06
TWI757759B (en)	2022-03-11
EA201790446A1 (en)	2017-07-31
CO2017003011A2 (en)	2017-07-11
US20190269786A1 (en)	2019-09-05
DK3189056T3 (en)	2020-09-14

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