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SG11201700201UA - Combination therapy for cancer - Google Patents

Combination therapy for cancer

Info

Publication number
SG11201700201UA
SG11201700201UA SG11201700201UA SG11201700201UA SG11201700201UA SG 11201700201U A SG11201700201U A SG 11201700201UA SG 11201700201U A SG11201700201U A SG 11201700201UA SG 11201700201U A SG11201700201U A SG 11201700201UA SG 11201700201U A SG11201700201U A SG 11201700201UA
Authority
SG
Singapore
Prior art keywords
cancer
combination therapy
therapy
combination
Prior art date
Application number
SG11201700201UA
Other languages
English (en)
Inventor
Michael Pourdehnad
Anita Gandhi
Kenichi Takeshita
Rajesh Chopra
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of SG11201700201UA publication Critical patent/SG11201700201UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG11201700201UA 2014-07-11 2015-07-10 Combination therapy for cancer SG11201700201UA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201462023748P 2014-07-11 2014-07-11
US201462033062P 2014-08-04 2014-08-04
US201462033566P 2014-08-05 2014-08-05
US201562149941P 2015-04-20 2015-04-20
US201562156928P 2015-05-05 2015-05-05
PCT/US2015/039939 WO2016007854A1 (fr) 2014-07-11 2015-07-10 Polythérapie contre le cancer

Publications (1)

Publication Number Publication Date
SG11201700201UA true SG11201700201UA (en) 2017-02-27

Family

ID=53682893

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201700201UA SG11201700201UA (en) 2014-07-11 2015-07-10 Combination therapy for cancer

Country Status (16)

Country Link
US (1) US20170128448A1 (fr)
EP (1) EP3166635A1 (fr)
JP (1) JP2017521396A (fr)
KR (1) KR20170029565A (fr)
CN (1) CN107073122A (fr)
AU (1) AU2015287694A1 (fr)
BR (1) BR112017000556A2 (fr)
CA (1) CA2954652A1 (fr)
CL (1) CL2017000050A1 (fr)
EA (1) EA201790164A1 (fr)
HK (1) HK1231381A1 (fr)
IL (1) IL249898A0 (fr)
MX (1) MX2017000366A (fr)
SG (1) SG11201700201UA (fr)
WO (1) WO2016007854A1 (fr)
ZA (1) ZA201608559B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009003038A (es) 2006-09-26 2009-04-15 Celgene Corp Derivados de quinazolinona 5-sustituidos como agentes antitumorales.
UA113512C2 (xx) 2011-03-11 2017-02-10 Тверда форма 3-(5-аміно-2-метил-4-оксо-4h-хіназолін-3-іл)піперидин-2,6-діону і її фармацевтична композиція та застосування
ES2814952T3 (es) 2012-09-04 2021-03-29 Celgene Corp Isotopólogos de 3-(5-amino-2-metil-4-oxoquinazolin-3(4H)-il) piperidina-2-6-diona y métodos de preparación de los mismos
JP6727237B2 (ja) 2015-07-02 2020-07-22 セルジーン コーポレイション 血液がん及び固形腫瘍の治療のための併用療法
US10159675B2 (en) * 2015-12-02 2018-12-25 Celgene Corporation Cycling therapy using 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione
WO2019083866A1 (fr) 2017-10-23 2019-05-02 Atara Biotherapeutics, Inc. Méthodes de gestion de la flambée tumorale liée à l'immunothérapie adoptive
EP3787751A1 (fr) 2018-05-03 2021-03-10 Juno Therapeutics, Inc. Polythérapie d'une thérapie par lymphocytes t à récepteur antigénique chimérique (car) et d'un inhibiteur de btk
US20230000956A1 (en) * 2019-10-08 2023-01-05 Memorial Sloan Kettering Cancer Center Combination therapy with glucarpidase with methotrexate/rituximab to treat cns lymphoma
JP7581345B2 (ja) 2019-10-21 2024-11-12 セルジーン コーポレーション 2-(2,6-ジオキソピペリジン-3-イル)-4-((2-フルオロ-4-((3-モルホリノアゼチジン-1-イル)メチル)ベンジル)アミノ)イソインドリン-1,3-ジオンを用いて慢性リンパ性白血病を治療する方法
CN115671295B (zh) * 2019-10-21 2025-10-28 新基公司 包含化合物的药物组合物及其使用方法
JP2025503176A (ja) * 2022-01-28 2025-01-30 ジェンマブ エー/エス びまん性大細胞型b細胞リンパ腫を治療するための併用療法におけるcd3及びcd20に対する二重特異性抗体
WO2023220655A1 (fr) 2022-05-11 2023-11-16 Celgene Corporation Méthodes pour surmonter la résistance aux médicaments par ré-sensibilisation de cellules cancéreuses à un traitement avec une thérapie antérieure par l'intermédiaire d'un traitement avec une thérapie par lymphocytes t
WO2024108028A1 (fr) * 2022-11-16 2024-05-23 Salarius Pharmaceuticals, Inc. Méthodes d'utilisation de composés enrichis en deutérium

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001052353A2 (fr) * 2000-01-12 2001-07-19 Emag Technologies L.L.C. Antenne imprimee omnidirectionnelle compacte et peu onereuse
US7346839B2 (en) * 2003-09-30 2008-03-18 Google Inc. Information retrieval based on historical data
US20060003059A1 (en) * 2004-07-02 2006-01-05 Burt Tabora Combined preparation and apparatus for use with a food blender and method for making preparation
TWI423039B (zh) * 2010-07-23 2014-01-11 Quanta Comp Inc 伺服器系統與其操作方法
JP6118273B2 (ja) * 2011-03-11 2017-04-19 セルジーン コーポレイション 免疫関連疾患及び炎症性疾患の治療における3−(5−アミノ−2−メチル−4−オキソキナゾリン−3(4h)−イル)ピペリジン−2,6−ジオンの使用
CA2909579A1 (fr) * 2013-04-17 2014-10-23 Signal Pharmaceuticals, Llc Therapie combinee comprenant un inhibiteur de la kinase tor et du n-(3-(5-fluoro-2-(4-(2-methoxyethoxy)phenylamino)pyrimidin-4-ylamino)phenyl)acrylamide pour le traitement d'un cancer
WO2014172429A1 (fr) * 2013-04-17 2014-10-23 Signal Pharmaceuticals, Llc Polythérapie comportant un inhibiteur de kinase tor et un composé imid pour le traitement du cancer
EP2986322A1 (fr) * 2013-04-17 2016-02-24 Signal Pharmaceuticals, LLC Polythérapie comprenant un inhibiteur de kinase tor et un composé de quinazolinone substitué en 5 pour le traitement du cancer
WO2014179661A1 (fr) * 2013-05-03 2014-11-06 Celgene Corporation Méthodes de traitement du cancer à l'aide d'une polythérapie

Also Published As

Publication number Publication date
EP3166635A1 (fr) 2017-05-17
CL2017000050A1 (es) 2017-08-11
WO2016007854A1 (fr) 2016-01-14
AU2015287694A1 (en) 2017-02-02
IL249898A0 (en) 2017-03-30
CN107073122A (zh) 2017-08-18
US20170128448A1 (en) 2017-05-11
ZA201608559B (en) 2018-04-25
KR20170029565A (ko) 2017-03-15
EA201790164A1 (ru) 2017-10-31
CA2954652A1 (fr) 2016-01-14
BR112017000556A2 (pt) 2017-11-07
MX2017000366A (es) 2017-04-27
JP2017521396A (ja) 2017-08-03
HK1231381A1 (zh) 2017-12-22

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