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SG11201609248WA - Nox inhibitor and nfκb inhibitor containing methoxyflavone - Google Patents

Nox inhibitor and nfκb inhibitor containing methoxyflavone

Info

Publication number
SG11201609248WA
SG11201609248WA SG11201609248WA SG11201609248WA SG11201609248WA SG 11201609248W A SG11201609248W A SG 11201609248WA SG 11201609248W A SG11201609248W A SG 11201609248WA SG 11201609248W A SG11201609248W A SG 11201609248WA SG 11201609248W A SG11201609248W A SG 11201609248WA
Authority
SG
Singapore
Prior art keywords
inhibitor
nox
nfκb
methoxyflavone
containing methoxyflavone
Prior art date
Application number
SG11201609248WA
Inventor
Daisuke Takemoto
Yoshiko Ono
Sumio Asami
Satomi Shimoyoshi
Original Assignee
Suntory Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Holdings Ltd filed Critical Suntory Holdings Ltd
Publication of SG11201609248WA publication Critical patent/SG11201609248WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/304Foods, ingredients or supplements having a functional effect on health having a modulation effect on allergy and risk of allergy
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
SG11201609248WA 2014-05-09 2015-05-01 Nox inhibitor and nfκb inhibitor containing methoxyflavone SG11201609248WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014097875 2014-05-09
PCT/JP2015/063100 WO2015170683A1 (en) 2014-05-09 2015-05-01 Nox inhibitor and nfκb inhibitor containing methoxyflavone

Publications (1)

Publication Number Publication Date
SG11201609248WA true SG11201609248WA (en) 2016-12-29

Family

ID=54392533

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201609248WA SG11201609248WA (en) 2014-05-09 2015-05-01 Nox inhibitor and nfκb inhibitor containing methoxyflavone
SG10201808940WA SG10201808940WA (en) 2014-05-09 2015-05-01 Nox inhibitor and nfкb inhibitor containing methoxyflavone

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201808940WA SG10201808940WA (en) 2014-05-09 2015-05-01 Nox inhibitor and nfкb inhibitor containing methoxyflavone

Country Status (9)

Country Link
US (1) US20170071902A1 (en)
JP (3) JP2015227329A (en)
KR (1) KR20170002565A (en)
CN (1) CN106456597A (en)
AU (1) AU2015256997B2 (en)
CA (1) CA2948127A1 (en)
SG (2) SG11201609248WA (en)
TW (1) TWI700278B (en)
WO (1) WO2015170683A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017145221A (en) * 2016-02-18 2017-08-24 株式会社レーネ Tau protein aggregation inhibitor
JP6909559B2 (en) * 2016-03-31 2021-07-28 株式会社アンチエイジングコミュニケーション OPH activity enhancer
JP6462755B2 (en) * 2017-04-04 2019-01-30 丸善製薬株式会社 Brain function improving agent and food and drink for improving brain function
TWI646943B (en) * 2017-12-08 2019-01-11 財團法人自行車暨健康科技工業研究發展中心 Method for screening for muscular dysfunction through functional fitness
KR102032739B1 (en) * 2018-01-31 2019-10-16 한림대학교 산학협력단 Pharmaceutical composition for preventing and treating diabetic complications containing the novel chrysin derivative
CN110237066B (en) * 2018-03-07 2022-03-29 上海市生物医药技术研究院 Application of 3-methoxyflavone and derivatives thereof in preparation of medicines for treating or preventing nephropathy
CN108904489A (en) * 2018-06-19 2018-11-30 杭州勃锐思莫生物医药科技有限责任公司 The purposes of the preventing respiratory diseases associated with inflammation of 3,4 ' flavonol of 5,7- methoxyl group
JP7229513B2 (en) * 2018-10-16 2023-02-28 丸善製薬株式会社 Brain function improving agent and food and drink for improving brain function
JP2022509359A (en) 2018-10-26 2022-01-20 ガラニン、アイバン Topical compositions and methods for promoting optimal dermal white adipose tissue formation in vivo
CN109288834A (en) * 2018-11-28 2019-02-01 武汉科技大学 Application of 5-methoxyflavones in the preparation of nonsense mutation read-through drugs
WO2020178267A1 (en) * 2019-03-04 2020-09-10 Universite D'aix-Marseille Nox inhibitors for preventing epileptic seizures
EA202193251A1 (en) 2019-06-05 2022-03-10 Эмори Юниверсити PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS
CN110357846B (en) * 2019-07-11 2021-06-15 上海健康医学院 A kind of flavonoid and monoterpenoid compound and its preparation method and application
KR20220120561A (en) * 2019-12-26 2022-08-30 마루젠세이야쿠 가부시키가이샤 Composition containing black ginger extract and composition for oral use
JP7467138B2 (en) * 2020-01-30 2024-04-15 株式会社 資生堂 Intestinal barrier improver
CN111374970B (en) * 2020-03-17 2023-05-30 广西壮族自治区中医药研究院 Composition with anti-colitis activity and application thereof
CN111617076B (en) * 2020-06-24 2021-09-28 江苏吴中医药集团有限公司 Compound pharmaceutical composition containing arbidol hydrochloride and application thereof
JP7081843B2 (en) * 2020-10-26 2022-06-07 株式会社東洋新薬 Autonomic nerve regulator
JPWO2022137964A1 (en) * 2020-12-23 2022-06-30
US20240415815A1 (en) 2022-01-26 2024-12-19 Universidade De Aveiro Ionic-liquid-based formulations for the prevention or treatment of neurological diseases
CN116650476B (en) * 2023-05-30 2025-09-09 南华大学附属第一医院 Compound, composition and application thereof in preparation of medicines for treating heart diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005505506A (en) * 2001-06-12 2005-02-24 イーラン ファーマスーティカルズ、インコーポレイテッド Macrocycles useful for the treatment of Alzheimer's disease
JP2007314468A (en) * 2006-05-25 2007-12-06 Meiji Milk Prod Co Ltd Endoplasmic reticulum stress control compound and pharmaceutical composition comprising the same
JP2009051790A (en) * 2007-08-29 2009-03-12 Maruzen Pharmaceut Co Ltd Antioxidant, anti-aging agent, anti-inflammatory agent, hair restoration agent, anti-obesity agent, skin-lightening agent, cosmetic and food and drink for cosmetic use
JP5756264B2 (en) * 2010-05-06 2015-07-29 日本タブレット株式会社 Xanthine oxidase inhibitor, xanthine oxidase and 5α-reductase inhibitor, and pharmaceutical composition containing the inhibitor
KR101811303B1 (en) * 2011-07-26 2017-12-26 에스케이하이닉스 주식회사 Semiconductor integrated circuit and method of driving the same
WO2013100111A1 (en) * 2011-12-27 2013-07-04 油田 正樹 Sirtuin activator
JP2013144659A (en) * 2012-01-16 2013-07-25 Nippon Tablet Kk 5α-REDUCTASE INHIBITOR AND FOOD, DRINK, COSMETIC COMPOSITION AND PHARMACEUTICAL COMPOSITION CONTAINING THE INHIBITOR
CN104411310B (en) * 2012-05-16 2018-03-16 Aat 考斯泰克有限公司 Use of kaempferia floret extract or flavonoids for prevention or treatment of muscle diseases and improvement of muscle function
JP2013241354A (en) * 2012-05-18 2013-12-05 Oriza Yuka Kk Phosphodiesterase 2 inhibitor
JP2013253047A (en) * 2012-06-07 2013-12-19 Kinki Univ Hemorheology improving agent, and food and drink and pharmaceutical composition including the same
WO2013185301A1 (en) * 2012-06-13 2013-12-19 Jin Yongri Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs

Also Published As

Publication number Publication date
JP2020063283A (en) 2020-04-23
JP2015227329A (en) 2015-12-17
JP6666837B2 (en) 2020-03-18
JPWO2015170683A1 (en) 2017-04-20
JP7015822B2 (en) 2022-02-15
TWI700278B (en) 2020-08-01
AU2015256997B2 (en) 2020-07-09
CN106456597A (en) 2017-02-22
CA2948127A1 (en) 2015-11-12
AU2015256997A1 (en) 2016-11-24
TW201625574A (en) 2016-07-16
US20170071902A1 (en) 2017-03-16
SG10201808940WA (en) 2018-11-29
WO2015170683A1 (en) 2015-11-12
KR20170002565A (en) 2017-01-06

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