SG11201607796TA - Nanopore-based analysis of protein characteristics - Google Patents
Nanopore-based analysis of protein characteristicsInfo
- Publication number
- SG11201607796TA SG11201607796TA SG11201607796TA SG11201607796TA SG11201607796TA SG 11201607796T A SG11201607796T A SG 11201607796TA SG 11201607796T A SG11201607796T A SG 11201607796TA SG 11201607796T A SG11201607796T A SG 11201607796TA SG 11201607796T A SG11201607796T A SG 11201607796TA
- Authority
- SG
- Singapore
- Prior art keywords
- nanopore
- based analysis
- protein characteristics
- protein
- analysis
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44743—Introducing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6818—Sequencing of polypeptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Nanotechnology (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461941919P | 2014-02-19 | 2014-02-19 | |
| PCT/US2014/067732 WO2015126494A1 (en) | 2014-02-19 | 2014-11-26 | Nanopore-based analysis of protein characteristics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201607796TA true SG11201607796TA (en) | 2016-11-29 |
Family
ID=53878776
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202111841TA SG10202111841TA (en) | 2014-02-19 | 2014-11-26 | Nanopore-based analysis of protein characteristics |
| SG11201607796TA SG11201607796TA (en) | 2014-02-19 | 2014-11-26 | Nanopore-based analysis of protein characteristics |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202111841TA SG10202111841TA (en) | 2014-02-19 | 2014-11-26 | Nanopore-based analysis of protein characteristics |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US10359395B2 (en) |
| EP (2) | EP3108229B1 (en) |
| CN (1) | CN106133513B (en) |
| ES (1) | ES3035698T3 (en) |
| SG (2) | SG10202111841TA (en) |
| WO (1) | WO2015126494A1 (en) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10359395B2 (en) | 2014-02-19 | 2019-07-23 | University Of Washington | Nanopore-based analysis of protein characteristics |
| SG11201609692SA (en) | 2014-06-03 | 2016-12-29 | Illumina Inc | Compositions, systems, and methods for detecting events using tethers anchored to or adjacent to nanopores |
| CN107835858B (en) | 2015-06-03 | 2022-04-12 | 亿明达股份有限公司 | Compositions, systems, and methods for sequencing polynucleotides using tethers anchored to polymerases adjacent to nanopores |
| AU2016326867B2 (en) * | 2015-09-22 | 2018-09-13 | F. Hoffmann-La Roche Ag | OmpG variants |
| US20190064110A1 (en) * | 2015-10-24 | 2019-02-28 | University Of Notre Dame | A picometer-diameter pore in an inorganic membrane for sequencing protein |
| KR102885764B1 (en) * | 2017-06-29 | 2025-11-13 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | Deterministic stepping of polymers through a nanopore |
| CN107942070B (en) * | 2017-11-16 | 2020-12-01 | 苏州市东挺河智能科技发展有限公司 | A nanobiomonitor for blood cruise and its emergency information AR display |
| EP3752284A4 (en) * | 2018-02-12 | 2022-05-25 | Oxford Nanopore Technologies plc | Nanopore assemblies and uses thereof |
| JP2020031557A (en) * | 2018-08-28 | 2020-03-05 | 株式会社日立ハイテクノロジーズ | Biomolecule analyzer |
| CN109270154A (en) * | 2018-10-29 | 2019-01-25 | 东南大学 | Based on the tetrahedral solid nano hole unimolecule protein detection method for amplifying signal of DNA and DNA tetrahedron |
| CN111499705B (en) * | 2019-01-30 | 2023-08-08 | 深圳市梅丽纳米孔科技有限公司 | Mutant NfpAB nanopore, testing system, manufacturing method and application |
| US12321837B2 (en) * | 2019-02-14 | 2025-06-03 | University Of Washington | Systems and methods for improved nanopore-based analysis of nucleic acids |
| CN112147185B (en) | 2019-06-29 | 2022-07-01 | 清华大学 | Method for controlling speed of polypeptide passing through nanopore and application of method |
| CN110729915B (en) * | 2019-11-20 | 2022-04-19 | 西南大学 | Preparation method of water supermolecule motor |
| NL2024579B1 (en) | 2019-12-24 | 2021-09-06 | Univ Delft Tech | Protein and peptide fingerprinting and sequencing by nanopore translocation of peptide-oligonucleotide complexes |
| CN112578106B (en) * | 2020-04-13 | 2022-04-22 | 南京大学 | Nano-pore single-molecule protein sequencer |
| WO2021208936A1 (en) * | 2020-04-14 | 2021-10-21 | 成都今是科技有限公司 | Nanopore preparation and detection method and detection apparatus thereof |
| CN111413383B (en) * | 2020-04-20 | 2021-03-02 | 深圳市梅丽纳米孔科技有限公司 | Method for constructing double-recognition-site nanopore |
| WO2022010935A2 (en) | 2020-07-08 | 2022-01-13 | Quan Qing | Method for constructing magnetic tunneling junction devices and use of device for spin-dependent transport characterization |
| JP2023549796A (en) * | 2020-11-13 | 2023-11-29 | ナンジン、ユニバーシティ | Programmable Nanoreactor for Probabilistic Sensing (PNRSS) |
| US12241857B2 (en) | 2021-03-16 | 2025-03-04 | Arizona Board Of Regents On Behalf Of Arizona State University | High density and multiplexed nanopore devices with transverse tunneling junction for biomolecule detection and sequencing |
| CN115219558A (en) * | 2021-04-15 | 2022-10-21 | 苏州罗岛纳米科技有限公司 | Method and equipment for positioning combination position of protein molecule and DNA |
| EP4352499A4 (en) * | 2021-05-13 | 2025-05-07 | Nanjing University | Structural-profiling of analytes by nanopore trapping |
| CN113322180B (en) * | 2021-05-31 | 2022-07-15 | 中国科学院物理研究所 | Force spectrum analysis method and analysis device based on nanopore sequencing |
| CN116165373A (en) * | 2021-08-30 | 2023-05-26 | 四川大学 | Polypeptide component analysis method based on copper ion modified MspA nanopore |
| CN114199971B (en) * | 2021-12-16 | 2024-03-22 | 中国科学院重庆绿色智能技术研究院 | Method for detecting integrin conformation based on chemically modified nanopores |
| CN115877018A (en) * | 2022-08-05 | 2023-03-31 | 四川大学华西医院 | Application of porin in preparation of kit for detecting dehydroepiandrosterone sulfate |
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| US6362002B1 (en) | 1995-03-17 | 2002-03-26 | President And Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
| WO2000039333A1 (en) | 1998-12-23 | 2000-07-06 | Jones Elizabeth Louise | Sequencing method using magnifying tags |
| US7258838B2 (en) | 1999-06-22 | 2007-08-21 | President And Fellows Of Harvard College | Solid state molecular probe device |
| US6800195B1 (en) | 2002-06-04 | 2004-10-05 | Thermaco, Inc. | Low cost grease removal system |
| EP1573043A2 (en) * | 2002-11-13 | 2005-09-14 | Pfizer Products Inc. | A continuous-read assay for the detection of de novo hcv rna polymerase activity |
| US7163658B2 (en) * | 2003-04-23 | 2007-01-16 | Rouvain Bension | Rapid sequencing of polymers |
| US7846738B2 (en) | 2003-08-15 | 2010-12-07 | President And Fellows Of Harvard College | Study of polymer molecules and conformations with a nanopore |
| WO2006028508A2 (en) * | 2004-03-23 | 2006-03-16 | President And Fellows Of Harvard College | Methods and apparatus for characterizing polynucleotides |
| US20130071837A1 (en) | 2004-10-06 | 2013-03-21 | Stephen N. Winters-Hilt | Method and System for Characterizing or Identifying Molecules and Molecular Mixtures |
| GB0504184D0 (en) | 2005-03-01 | 2005-04-06 | Lingvitae As | Method |
| US20110005918A1 (en) | 2007-04-04 | 2011-01-13 | Akeson Mark A | Compositions, devices, systems, and methods for using a nanopore |
| EP2195648B1 (en) | 2007-09-12 | 2019-05-08 | President and Fellows of Harvard College | High-resolution molecular graphene sensor comprising an aperture in the graphene layer |
| JP5309145B2 (en) | 2007-10-02 | 2013-10-09 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | Molecular capture, recapture and trapping by nanopores |
| CA2931824C (en) * | 2008-09-22 | 2020-09-08 | University Of Washington | Msp nanopores and related methods |
| KR20110125226A (en) | 2009-01-30 | 2011-11-18 | 옥스포드 나노포어 테크놀로지즈 리미티드 | Hybridization linker |
| DE202009004160U1 (en) | 2009-03-25 | 2009-05-28 | Burgmann Industries Gmbh & Co. Kg | Thermally decoupled bearing arrangement |
| US9017937B1 (en) * | 2009-04-10 | 2015-04-28 | Pacific Biosciences Of California, Inc. | Nanopore sequencing using ratiometric impedance |
| CA2772789C (en) | 2009-09-18 | 2018-10-30 | President And Fellows Of Harvard College | Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis |
| US8324914B2 (en) | 2010-02-08 | 2012-12-04 | Genia Technologies, Inc. | Systems and methods for characterizing a molecule |
| CA3211104A1 (en) * | 2010-02-23 | 2011-09-01 | University Of Washington | Artificial mycolic acid membranes |
| AR077206A1 (en) | 2010-06-23 | 2011-08-10 | Consejo Nac Invest Cient Tec | QUANTIFICATION METHOD OF THE ABSORPTION OF MAGNETIC NANOPARTICLES IN ANIMAL FABRICS, AND EQUIPMENT TO PERFORM IT |
| CN103392008B (en) * | 2010-09-07 | 2017-10-20 | 加利福尼亚大学董事会 | Movement by continuation enzyme with the precision controlling DNA of a nucleotides in nano-pore |
| CN103370617B (en) | 2010-10-01 | 2015-11-25 | 牛津纳米孔技术有限公司 | Biochemical analysis equipment and rotary valves |
| CN103460040B (en) * | 2011-02-11 | 2016-08-17 | 牛津纳米孔技术有限公司 | mutant hole |
| IN2014DN00221A (en) | 2011-07-25 | 2015-06-05 | Oxford Nanopore Tech Ltd | |
| EP2987870B1 (en) | 2011-10-21 | 2020-02-19 | Oxford Nanopore Technologies Limited | Method of characterizing a target polynucleotide using a transmembrane pore and molecular motor |
| US9267917B2 (en) | 2011-11-04 | 2016-02-23 | Pacific Biosciences Of California, Inc. | Nanopores in zero mode waveguides |
| GB201120910D0 (en) | 2011-12-06 | 2012-01-18 | Cambridge Entpr Ltd | Nanopore functionality control |
| JP6228128B2 (en) * | 2011-12-29 | 2017-11-08 | オックスフォード ナノポール テクノロジーズ リミテッド | Enzyme method |
| US20130256139A1 (en) * | 2012-03-30 | 2013-10-03 | International Business Machines Corporation | Functionalized graphene or graphene oxide nanopore for bio-molecular sensing and dna sequencing |
| KR102083695B1 (en) | 2012-04-10 | 2020-03-02 | 옥스포드 나노포어 테크놀로지즈 리미티드 | Mutant lysenin pores |
| WO2013159042A1 (en) | 2012-04-19 | 2013-10-24 | University Of Washington Through Its Center For Commercialization | Methods and compositions for generating reference maps for nanopore-based polymer analysis |
| CN103509852B (en) | 2012-06-18 | 2014-11-19 | 北京大学 | A method for detecting specific sites of biomolecular probe-marked DNA based on nanopore devices |
| US10808231B2 (en) | 2012-07-19 | 2020-10-20 | Oxford Nanopore Technologies Limited | Modified helicases |
| DK3527280T3 (en) | 2013-08-30 | 2021-08-30 | Univ Washington Through Its Center For Commercialization | Selective modification of polymer subunits to enhance nanopore-based analysis |
| WO2015051378A1 (en) | 2013-10-04 | 2015-04-09 | University Of Washington Through Its Center For Commercialization | Systems and methods for nanopore-based analysis of nucleic acids |
| DK3074534T3 (en) * | 2013-11-26 | 2019-07-29 | Illumina Inc | Polynucleotide Sequencing Methods |
| US10359395B2 (en) * | 2014-02-19 | 2019-07-23 | University Of Washington | Nanopore-based analysis of protein characteristics |
-
2014
- 2014-11-26 US US15/120,286 patent/US10359395B2/en active Active
- 2014-11-26 SG SG10202111841TA patent/SG10202111841TA/en unknown
- 2014-11-26 ES ES14883310T patent/ES3035698T3/en active Active
- 2014-11-26 CN CN201480077395.3A patent/CN106133513B/en active Active
- 2014-11-26 SG SG11201607796TA patent/SG11201607796TA/en unknown
- 2014-11-26 EP EP14883310.6A patent/EP3108229B1/en active Active
- 2014-11-26 EP EP25172584.2A patent/EP4603838A3/en active Pending
- 2014-11-26 WO PCT/US2014/067732 patent/WO2015126494A1/en not_active Ceased
-
2019
- 2019-07-22 US US16/517,996 patent/US10948454B2/en active Active
-
2021
- 2021-03-15 US US17/202,118 patent/US11808734B2/en active Active
-
2023
- 2023-09-27 US US18/475,534 patent/US12085533B2/en active Active
-
2024
- 2024-07-31 US US18/789,966 patent/US20240377357A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN106133513B (en) | 2019-08-13 |
| US20200049656A1 (en) | 2020-02-13 |
| EP4603838A3 (en) | 2025-11-19 |
| CN106133513A (en) | 2016-11-16 |
| EP3108229A1 (en) | 2016-12-28 |
| US11808734B2 (en) | 2023-11-07 |
| US12085533B2 (en) | 2024-09-10 |
| US20170199149A1 (en) | 2017-07-13 |
| US10359395B2 (en) | 2019-07-23 |
| EP4603838A2 (en) | 2025-08-20 |
| US10948454B2 (en) | 2021-03-16 |
| EP3108229C0 (en) | 2025-06-18 |
| US20240085372A1 (en) | 2024-03-14 |
| US20240377357A1 (en) | 2024-11-14 |
| ES3035698T3 (en) | 2025-09-08 |
| EP3108229B1 (en) | 2025-06-18 |
| US20210293748A1 (en) | 2021-09-23 |
| WO2015126494A1 (en) | 2015-08-27 |
| EP3108229A4 (en) | 2017-09-06 |
| SG10202111841TA (en) | 2021-12-30 |
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