SG11201605597VA - Duocarmycin adcs for use in treatment of endometrial cancer - Google Patents
Duocarmycin adcs for use in treatment of endometrial cancerInfo
- Publication number
- SG11201605597VA SG11201605597VA SG11201605597VA SG11201605597VA SG11201605597VA SG 11201605597V A SG11201605597V A SG 11201605597VA SG 11201605597V A SG11201605597V A SG 11201605597VA SG 11201605597V A SG11201605597V A SG 11201605597VA SG 11201605597V A SG11201605597V A SG 11201605597VA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- endometrial cancer
- duocarmycin
- adcs
- duocarmycin adcs
- Prior art date
Links
Classifications
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Veterinary Medicine (AREA)
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- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14150791 | 2014-01-10 | ||
| PCT/EP2015/050332 WO2015104373A2 (en) | 2014-01-10 | 2015-01-09 | Duocarmycin adcs for use in treatment of endometrial cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201605597VA true SG11201605597VA (en) | 2016-08-30 |
Family
ID=49917013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201605597VA SG11201605597VA (en) | 2014-01-10 | 2015-01-09 | Duocarmycin adcs for use in treatment of endometrial cancer |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US9427480B2 (pl) |
| EP (1) | EP2948183B1 (pl) |
| JP (1) | JP6224268B2 (pl) |
| KR (2) | KR20160099725A (pl) |
| CN (1) | CN105899237B (pl) |
| AU (1) | AU2015205588B2 (pl) |
| CA (1) | CA2935430C (pl) |
| CL (1) | CL2016001743A1 (pl) |
| CY (1) | CY1117712T1 (pl) |
| DK (1) | DK2948183T3 (pl) |
| ES (1) | ES2578831T3 (pl) |
| HR (1) | HRP20160797T1 (pl) |
| HU (1) | HUE029672T2 (pl) |
| MX (1) | MX368234B (pl) |
| MY (1) | MY189713A (pl) |
| PL (1) | PL2948183T3 (pl) |
| PT (1) | PT2948183T (pl) |
| RU (1) | RU2686085C2 (pl) |
| SG (1) | SG11201605597VA (pl) |
| WO (1) | WO2015104373A2 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9901567B2 (en) | 2007-08-01 | 2018-02-27 | Syntarga B.V. | Substituted CC-1065 analogs and their conjugates |
| HUE035798T2 (en) | 2008-11-03 | 2018-05-28 | Syntarga Bv | CC-1065 analogues and conjugates |
| HUE030846T2 (en) | 2010-04-21 | 2017-06-28 | Syntarga Bv | Conjugates of cc-1065 analogs and bifunctional linkers |
| EP2948184B1 (en) | 2014-01-10 | 2016-03-23 | Synthon Biopharmaceuticals B.V. | Duocarmycin adcs showing improved in vivo antitumor activity |
| LT3092010T (lt) | 2014-01-10 | 2018-10-25 | Synthon Biopharmaceuticals B.V. | Metodas, skirtas gryninimui cys-sujungtų antikūno-vaisto konjugatų |
| RU2686085C2 (ru) | 2014-01-10 | 2019-04-24 | Синтон Байофармасьютикалс Б. В. | Конъюгаты антитело-лекарственное средство (adc) с дуокармицином, применяемые для лечения рака эндометрия |
| KR102419766B1 (ko) | 2014-05-22 | 2022-07-13 | 비온디스 비.브이. | 항체에 대한 링커 약물의 부위 특이적 접합 및 그 결과로 얻어지는 adc |
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