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SG11201604371PA - Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease - Google Patents

Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease

Info

Publication number
SG11201604371PA
SG11201604371PA SG11201604371PA SG11201604371PA SG11201604371PA SG 11201604371P A SG11201604371P A SG 11201604371PA SG 11201604371P A SG11201604371P A SG 11201604371PA SG 11201604371P A SG11201604371P A SG 11201604371PA SG 11201604371P A SG11201604371P A SG 11201604371PA
Authority
SG
Singapore
Prior art keywords
pharmaceutical composition
inflammatory disease
metabolic syndrome
phenol derivative
treating metabolic
Prior art date
Application number
SG11201604371PA
Inventor
Sang Ku Yoo
Jin Wook Chung
In Geun Jo
Jeong Ho Im
Ku Suk Kang
Jin Young Kim
Original Assignee
Erum Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erum Biotechnologies Inc filed Critical Erum Biotechnologies Inc
Publication of SG11201604371PA publication Critical patent/SG11201604371PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D497/00Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SG11201604371PA 2013-12-24 2014-12-23 Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease SG11201604371PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20130162909 2013-12-24
KR1020140181951A KR102344479B1 (en) 2013-12-24 2014-12-17 Pyranochromenylphenol derivatives and a pharmaceutical composition for treating metabolic syndrome or inflammatory disease
PCT/KR2014/012688 WO2015099392A1 (en) 2013-12-24 2014-12-23 Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease

Publications (1)

Publication Number Publication Date
SG11201604371PA true SG11201604371PA (en) 2016-07-28

Family

ID=53788040

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201604371PA SG11201604371PA (en) 2013-12-24 2014-12-23 Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease

Country Status (21)

Country Link
US (1) US9783551B2 (en)
EP (1) EP3098224B1 (en)
JP (2) JP6620096B2 (en)
KR (1) KR102344479B1 (en)
CN (1) CN105849111B (en)
AU (1) AU2014370697B2 (en)
BR (1) BR112016011281B1 (en)
CA (1) CA2929001C (en)
CY (1) CY1121554T1 (en)
DK (1) DK3098224T3 (en)
ES (1) ES2718878T3 (en)
HR (1) HRP20190573T1 (en)
HU (1) HUE043902T2 (en)
IL (1) IL245908B (en)
MX (1) MX374944B (en)
NZ (1) NZ720328A (en)
PL (1) PL3098224T3 (en)
PT (1) PT3098224T (en)
SG (1) SG11201604371PA (en)
TW (1) TWI585093B (en)
WO (1) WO2015099392A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102344479B1 (en) * 2013-12-24 2021-12-29 주식회사 글라세움 Pyranochromenylphenol derivatives and a pharmaceutical composition for treating metabolic syndrome or inflammatory disease
ES2964146T3 (en) * 2016-06-29 2024-04-04 Glaceum Inc Optically active pyranochromenylphenol derivative and pharmaceutical composition comprising it
PT3524609T (en) * 2016-10-04 2021-07-15 Glaceum Inc 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and method for synthesizing optical isomer thereof
TWI804600B (en) 2018-04-03 2023-06-11 南韓商格雷森伍股份有限公司 METHOD FOR SYNTHESIZING 3-PHENYL-2,8-DIHYDROPYRANO[2,3-ƒ]CHROMENE DERIVATIVES
WO2019194583A1 (en) * 2018-04-03 2019-10-10 주식회사 글라세움 3-phenyl-2,8-dihydropyrano[2,3-f]chromene derivative and pharmaceutical composition comprising same
KR20200105198A (en) 2019-02-28 2020-09-07 주식회사 글라세움 Pharmaceutical composition for the prevention or treatment of neurological diseases
KR102692932B1 (en) 2019-07-30 2024-08-07 주식회사 글라세움 Synthesizing Method Of 2-((6-(hydroxymethyl)chromene-5-yl)oxy)-1-phenylethanone Derivative
EP4353226A4 (en) 2021-06-08 2024-10-16 Glaceum, Inc. Pharmaceutical composition for preventing or treating degenerative eye diseases
CN113616548B (en) * 2021-09-02 2023-04-28 河南科技大学 Water-soluble glabridin inclusion compound and preparation method thereof
US20250250279A1 (en) * 2022-04-12 2025-08-07 Glaceum Inc. METHOD FOR SYNTHESIZING 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-f]CHROMENE DERIVATIVES
CN114903879B (en) * 2022-06-23 2023-10-31 东北大学 Use of 3-hydrocarbylphenol derivatives in the preparation of products for preventing or treating hyperlipidemia and related metabolic diseases
KR20240113389A (en) 2023-01-12 2024-07-22 주식회사 글라세움 Pharmaceutical composition for the prevention or treatment of degenerative arthritis
KR20250081177A (en) 2023-11-29 2025-06-05 한국화학연구원 Composition for preventing, improving or treating obesity in companion animals containing HSG4112 R-form as an active ingredient

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL160964A0 (en) 2001-10-11 2004-08-31 Kaneka Corp Peroxisome proliferator activated receptor ligand and process for producing the same
KR100565423B1 (en) * 2003-10-20 2006-03-30 빅 바이오 주식회사 Method for preparing isoflavone derivatives or isoflavone derivatives
JP2006008604A (en) 2004-06-25 2006-01-12 Kuraray Co Ltd Method for producing isoflavan derivative
KR20070052211A (en) * 2005-11-16 2007-05-21 주식회사 엠디바이오알파 Composition for preventing and treating disease syndrome containing glabridine as an active ingredient
KR102344479B1 (en) * 2013-12-24 2021-12-29 주식회사 글라세움 Pyranochromenylphenol derivatives and a pharmaceutical composition for treating metabolic syndrome or inflammatory disease

Also Published As

Publication number Publication date
KR102344479B1 (en) 2021-12-29
CA2929001C (en) 2018-02-20
BR112016011281A2 (en) 2017-08-08
IL245908B (en) 2020-08-31
JP6620096B2 (en) 2019-12-11
DK3098224T3 (en) 2019-05-13
US20160272650A1 (en) 2016-09-22
MX2016008429A (en) 2017-02-23
JP2018135343A (en) 2018-08-30
PT3098224T (en) 2019-04-26
HUE043902T2 (en) 2019-10-28
AU2014370697A1 (en) 2016-06-16
MX374944B (en) 2025-03-06
PL3098224T3 (en) 2019-07-31
CN105849111A (en) 2016-08-10
WO2015099392A1 (en) 2015-07-02
EP3098224A1 (en) 2016-11-30
TW201607949A (en) 2016-03-01
BR112016011281B1 (en) 2021-11-16
KR20150075030A (en) 2015-07-02
JP2017501163A (en) 2017-01-12
EP3098224B1 (en) 2019-01-30
CN105849111B (en) 2018-05-04
CA2929001A1 (en) 2015-07-02
TWI585093B (en) 2017-06-01
CY1121554T1 (en) 2020-05-29
US9783551B2 (en) 2017-10-10
HRP20190573T1 (en) 2019-05-17
AU2014370697B2 (en) 2017-01-19
NZ720328A (en) 2018-02-23
IL245908A0 (en) 2016-08-02
ES2718878T3 (en) 2019-07-05
EP3098224A4 (en) 2017-07-05

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