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SG11201604965RA - Differentiation therapy with cd137 ligand agonists - Google Patents

Differentiation therapy with cd137 ligand agonists

Info

Publication number
SG11201604965RA
SG11201604965RA SG11201604965RA SG11201604965RA SG11201604965RA SG 11201604965R A SG11201604965R A SG 11201604965RA SG 11201604965R A SG11201604965R A SG 11201604965RA SG 11201604965R A SG11201604965R A SG 11201604965RA SG 11201604965R A SG11201604965R A SG 11201604965RA
Authority
SG
Singapore
Prior art keywords
differentiation therapy
ligand agonists
agonists
ligand
differentiation
Prior art date
Application number
SG11201604965RA
Inventor
Herbert Schwarz
Cheong Kin Cheng
Original Assignee
Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Singapore filed Critical Univ Singapore
Priority to SG11201604965RA priority Critical patent/SG11201604965RA/en
Publication of SG11201604965RA publication Critical patent/SG11201604965RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201604965RA 2013-12-20 2014-12-18 Differentiation therapy with cd137 ligand agonists SG11201604965RA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG11201604965RA SG11201604965RA (en) 2013-12-20 2014-12-18 Differentiation therapy with cd137 ligand agonists

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG2013094545 2013-12-20
PCT/SG2014/000606 WO2015094123A1 (en) 2013-12-20 2014-12-18 Differentiation therapy with cd137 ligand agonists
SG11201604965RA SG11201604965RA (en) 2013-12-20 2014-12-18 Differentiation therapy with cd137 ligand agonists

Publications (1)

Publication Number Publication Date
SG11201604965RA true SG11201604965RA (en) 2016-07-28

Family

ID=53403270

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201604965RA SG11201604965RA (en) 2013-12-20 2014-12-18 Differentiation therapy with cd137 ligand agonists

Country Status (4)

Country Link
US (1) US20170000850A1 (en)
EP (1) EP3082839A4 (en)
SG (1) SG11201604965RA (en)
WO (1) WO2015094123A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018137045A1 (en) 2017-01-30 2018-08-02 Litens Automotive Partnership Clutched vacuum pump system
CN111511762B (en) 2017-08-21 2025-05-06 天演药业公司 Anti-CD137 molecules and their uses
WO2019094710A1 (en) * 2017-11-09 2019-05-16 Duke University Lymphovascular invasion bioreactor and methods of making and using same
WO2019104716A1 (en) * 2017-12-01 2019-06-06 Adagene Inc. Methods for using cd137 ligand as biomarker for treatment with anti-cd137 antibody
WO2019148445A1 (en) 2018-02-02 2019-08-08 Adagene Inc. Precision/context-dependent activatable antibodies, and methods of making and using the same
CN113366117B (en) * 2018-08-28 2025-08-05 10X基因组学股份有限公司 Methods for transposase-mediated spatial labeling and analysis of genomic DNA in biological samples
SG11202113221RA (en) * 2019-06-05 2021-12-30 Adagene Pte Ltd Anti-cd137l antibodies and methods of using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050232896A1 (en) * 2001-10-04 2005-10-20 Herbert Schwarz Cd137 as a proliferation factor for hematopoietic stem cells
US20060121030A1 (en) * 2002-12-16 2006-06-08 Herbert Schwarz Use of cd 137 antagonists for the treatment of tumors
ES2336873B1 (en) * 2007-11-07 2011-01-24 Proyecto De Biomedicina Cima, S.L. PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT.

Also Published As

Publication number Publication date
EP3082839A4 (en) 2017-08-09
US20170000850A1 (en) 2017-01-05
WO2015094123A1 (en) 2015-06-25
EP3082839A1 (en) 2016-10-26

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