SG11201603131RA - Tau imaging probe - Google Patents
Tau imaging probeInfo
- Publication number
- SG11201603131RA SG11201603131RA SG11201603131RA SG11201603131RA SG11201603131RA SG 11201603131R A SG11201603131R A SG 11201603131RA SG 11201603131R A SG11201603131R A SG 11201603131RA SG 11201603131R A SG11201603131R A SG 11201603131RA SG 11201603131R A SG11201603131R A SG 11201603131RA
- Authority
- SG
- Singapore
- Prior art keywords
- imaging probe
- tau imaging
- tau
- probe
- imaging
- Prior art date
Links
- 238000003384 imaging method Methods 0.000 title 1
- 239000000523 sample Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Optics & Photonics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013233470 | 2013-10-22 | ||
| PCT/JP2014/078146 WO2015060365A1 (en) | 2013-10-22 | 2014-10-22 | Tau imaging probe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201603131RA true SG11201603131RA (en) | 2016-05-30 |
Family
ID=52992954
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201803294PA SG10201803294PA (en) | 2013-10-22 | 2014-10-22 | Tau imaging probe |
| SG11201603131RA SG11201603131RA (en) | 2013-10-22 | 2014-10-22 | Tau imaging probe |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201803294PA SG10201803294PA (en) | 2013-10-22 | 2014-10-22 | Tau imaging probe |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20160244411A1 (en) |
| EP (1) | EP3061748A4 (en) |
| JP (1) | JPWO2015060365A1 (en) |
| KR (1) | KR20160072226A (en) |
| CN (1) | CN105814023A (en) |
| AU (1) | AU2014338155B2 (en) |
| BR (1) | BR112016008871A8 (en) |
| CA (1) | CA2928313A1 (en) |
| IL (1) | IL245221A0 (en) |
| MX (1) | MX2016005233A (en) |
| RU (1) | RU2016119524A (en) |
| SG (2) | SG10201803294PA (en) |
| WO (1) | WO2015060365A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201522414D0 (en) * | 2015-12-18 | 2016-02-03 | Clino Ltd | Monoamine oxidase B binders |
| ES2846833T3 (en) | 2016-07-18 | 2021-07-29 | Janssen Pharmaceutica Nv | PET imaging ligands |
| WO2019014429A1 (en) * | 2017-07-12 | 2019-01-17 | Dana-Farber Cancer Institute, Inc. | Compounds for tau protein degradation |
| CN107488144B (en) * | 2017-08-09 | 2021-06-04 | 复旦大学 | Molecule capable of specifically binding and inhibiting Tau protein aggregation and preparation method and application thereof |
| JP7284490B2 (en) | 2018-08-07 | 2023-05-31 | 国立大学法人東北大学 | Monoamine oxidase B imaging probe |
| KR102344676B1 (en) | 2020-02-12 | 2021-12-30 | 한국과학기술연구원 | Novel compounds useful as near infrared fluorescent probes selectively binding to tau aggregates and preparation method thereof |
| KR20210128125A (en) * | 2020-04-16 | 2021-10-26 | 연세대학교 산학협력단 | A Contrast Agent Composition for Detecting Lesional Margin of Dementia Caused by Degenerative Brain Disease Comprising Quinoline Derivatives as Active Ingredients |
| KR102369838B1 (en) * | 2020-04-16 | 2022-03-04 | 연세대학교 산학협력단 | A Contrast Agent Composition for Detecting Lesional Margin of Astrocytosis-Related Disease Comprising Quinoline Derivatives as Active Ingredients |
| CN111892534A (en) * | 2020-08-04 | 2020-11-06 | 中国科学技术大学 | A pH-sensitive fluorescent probe, its preparation method and its application |
| CN113754583A (en) * | 2021-09-03 | 2021-12-07 | 湖南工程学院 | 2- ([2, 2' -biquinolyl ] -3-ether) -1-ethanol and derivative and synthetic method thereof |
| CN113999172A (en) * | 2021-11-17 | 2022-02-01 | 湖南工程学院 | 2- ((2-phenylquinoline-3-yl) ether) -1-ethanol and derivative and synthetic method thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2004054978A1 (en) * | 2002-12-16 | 2006-04-20 | 株式会社 ビーエフ研究所 | Quinoline derivatives as diagnostic probes for tau protein storage diseases |
| ES2797523T3 (en) | 2009-03-23 | 2020-12-02 | Lilly Co Eli | Imaging agents to detect neurological disorders |
| US8691187B2 (en) * | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
| US8483197B2 (en) * | 2009-03-23 | 2013-07-09 | Qualcomm Incorporated | AP to legacy station SDMA protocol |
| KR101101977B1 (en) | 2009-04-09 | 2012-01-02 | (주)에스메디 | 2-arylnaphthalene, 2-arylquinoline derivative or pharmaceutically acceptable salt thereof, preparation method thereof, and pharmaceutical composition for diagnosis or treatment of degenerative brain disease containing the same as an active ingredient |
| DK2634177T3 (en) * | 2010-10-29 | 2016-08-15 | Clino Ltd | TAU IMAGE SOUND |
| US9040021B2 (en) * | 2010-11-16 | 2015-05-26 | Ge Healthcare Limited | Heterocyclic compounds as imaging probes of tau pathology |
| GB201411571D0 (en) * | 2014-06-30 | 2014-08-13 | Ge Healthcare Ltd | Radiolabelling method |
-
2014
- 2014-10-22 SG SG10201803294PA patent/SG10201803294PA/en unknown
- 2014-10-22 CA CA2928313A patent/CA2928313A1/en not_active Abandoned
- 2014-10-22 MX MX2016005233A patent/MX2016005233A/en unknown
- 2014-10-22 BR BR112016008871A patent/BR112016008871A8/en not_active Application Discontinuation
- 2014-10-22 EP EP14855618.6A patent/EP3061748A4/en not_active Withdrawn
- 2014-10-22 KR KR1020167013070A patent/KR20160072226A/en not_active Withdrawn
- 2014-10-22 CN CN201480070144.2A patent/CN105814023A/en active Pending
- 2014-10-22 US US15/030,924 patent/US20160244411A1/en not_active Abandoned
- 2014-10-22 AU AU2014338155A patent/AU2014338155B2/en not_active Ceased
- 2014-10-22 SG SG11201603131RA patent/SG11201603131RA/en unknown
- 2014-10-22 JP JP2015543896A patent/JPWO2015060365A1/en active Pending
- 2014-10-22 WO PCT/JP2014/078146 patent/WO2015060365A1/en not_active Ceased
- 2014-10-22 RU RU2016119524A patent/RU2016119524A/en not_active Application Discontinuation
-
2016
- 2016-04-20 IL IL245221A patent/IL245221A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL245221A0 (en) | 2016-06-30 |
| EP3061748A1 (en) | 2016-08-31 |
| KR20160072226A (en) | 2016-06-22 |
| WO2015060365A1 (en) | 2015-04-30 |
| CN105814023A (en) | 2016-07-27 |
| EP3061748A4 (en) | 2017-04-05 |
| RU2016119524A3 (en) | 2018-06-14 |
| BR112016008871A8 (en) | 2020-03-24 |
| US20160244411A1 (en) | 2016-08-25 |
| SG10201803294PA (en) | 2018-06-28 |
| RU2016119524A (en) | 2017-11-28 |
| MX2016005233A (en) | 2017-01-05 |
| AU2014338155B2 (en) | 2018-08-23 |
| AU2014338155A1 (en) | 2016-05-19 |
| CA2928313A1 (en) | 2015-04-30 |
| JPWO2015060365A1 (en) | 2017-03-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB201315248D0 (en) | Imaging | |
| IL240271A0 (en) | Multiple-swath stripmap sar imaging | |
| EP2951642A4 (en) | OMNISTEREO IMAGING | |
| GB201304149D0 (en) | Ultrasound imaging | |
| PT2846180T (en) | Stereoscopic imaging device | |
| EP3007435A4 (en) | Solid state imaging apparatus | |
| IL245221A0 (en) | Tau imaging probe | |
| EP3076432A4 (en) | Imaging element | |
| GB201318404D0 (en) | An image sensor | |
| SG11201507628WA (en) | Medical imaging | |
| EP2951582A4 (en) | Testing device | |
| EP3028622A4 (en) | Imaging device | |
| EP3077009A4 (en) | Molecular imaging probes | |
| GB2518957B (en) | Imaging apparatus | |
| EP2933672A4 (en) | Imaging optics | |
| EP3041214A4 (en) | Imaging device | |
| EP3021577A4 (en) | Imaging device | |
| EP3026489A4 (en) | Imaging device | |
| GB2510372B (en) | Imaging sensor | |
| EP2980838A4 (en) | Probe device | |
| GB2521888B (en) | Ultrasound testing | |
| PL2976637T3 (en) | Testing device | |
| GB201410076D0 (en) | Testing device | |
| EP2980561A4 (en) | Imaging system | |
| EP3000380A4 (en) | Imaging device |