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SG11201603118TA - A telomerase encoding dna vaccine - Google Patents

A telomerase encoding dna vaccine

Info

Publication number
SG11201603118TA
SG11201603118TA SG11201603118TA SG11201603118TA SG11201603118TA SG 11201603118T A SG11201603118T A SG 11201603118TA SG 11201603118T A SG11201603118T A SG 11201603118TA SG 11201603118T A SG11201603118T A SG 11201603118TA SG 11201603118T A SG11201603118T A SG 11201603118TA
Authority
SG
Singapore
Prior art keywords
encoding dna
dna vaccine
telomerase
telomerase encoding
vaccine
Prior art date
Application number
SG11201603118TA
Inventor
Demoyen Pierre Langlade
Simon Wain-Hobson
Thierry Huet
Christelle Liard
Elodie Pliquet
Original Assignee
Invectys
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Invectys filed Critical Invectys
Publication of SG11201603118TA publication Critical patent/SG11201603118TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001154Enzymes
    • A61K39/001157Telomerase or TERT [telomerase reverse transcriptase]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1276RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/35Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07Nucleotidyltransferases (2.7.7)
    • C12Y207/07049RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
SG11201603118TA 2013-10-28 2014-10-28 A telomerase encoding dna vaccine SG11201603118TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13190547 2013-10-28
PCT/EP2014/073164 WO2015063117A1 (en) 2013-10-28 2014-10-28 A telomerase encoding dna vaccine

Publications (1)

Publication Number Publication Date
SG11201603118TA true SG11201603118TA (en) 2016-05-30

Family

ID=49515221

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201603118TA SG11201603118TA (en) 2013-10-28 2014-10-28 A telomerase encoding dna vaccine

Country Status (25)

Country Link
US (2) US10183065B2 (en)
EP (2) EP3666290A1 (en)
JP (1) JP6545162B2 (en)
KR (1) KR102252756B1 (en)
CN (1) CN106061509B (en)
AU (1) AU2014343813B2 (en)
BR (1) BR112016009002B1 (en)
CA (1) CA2927702C (en)
CY (1) CY1122839T1 (en)
DK (1) DK3062824T3 (en)
EA (1) EA034928B1 (en)
ES (1) ES2771862T3 (en)
HR (1) HRP20200211T1 (en)
HU (1) HUE047898T2 (en)
IL (1) IL245186B (en)
LT (1) LT3062824T (en)
MX (1) MX372778B (en)
NZ (1) NZ719098A (en)
PL (1) PL3062824T3 (en)
PT (1) PT3062824T (en)
RS (1) RS60232B1 (en)
SG (1) SG11201603118TA (en)
SI (1) SI3062824T1 (en)
WO (1) WO2015063117A1 (en)
ZA (1) ZA201603452B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3062824T (en) 2013-10-28 2020-02-21 Invectys TELOMERASE CODING DNA VACCINE
WO2017060360A1 (en) * 2015-10-06 2017-04-13 Invectys Polyepitope constructs for use in immunotherapy
US11351246B2 (en) 2017-05-09 2022-06-07 Invectys SAS Recombinant measles vaccine expressing hTERT
US20220307053A1 (en) * 2019-07-25 2022-09-29 Novartis Ag Regulatable expression systems
EP4103717A4 (en) * 2020-02-12 2024-02-28 The Children's Hospital of Philadelphia COMPOSITIONS AND METHODS FOR INDUCIBLE ALTERNATIVE SPLICING REGULATION OF GENE EXPRESSION
EP4171619A4 (en) * 2020-06-26 2024-08-07 National Breast Cancer Coalition BREAST CANCER VACCINE
AU2021298886A1 (en) * 2020-07-03 2023-02-09 Statens Serum Institut A dna plasmid SARS-Coronavirus-2/covid-19 vaccine
CN116870195A (en) * 2020-09-22 2023-10-13 浙江愈方生物科技有限公司 Inactivated telomerase, adenovirus and artificial mRNA with same and application
WO2022236301A1 (en) * 2021-05-05 2022-11-10 Inovio Pharmaceuticals Inc. Vaccines against coronavirus and methods of use
WO2024126758A2 (en) * 2022-12-14 2024-06-20 Ultimovacs Ab A nucleic acid molecule and a chimeric polypeptide

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2075196T3 (en) 1989-02-17 1995-10-01 Chiron Mimotopes Pty Ltd METHOD FOR USE AND SYNTHESIS OF PEPTIDES.
US5840839A (en) 1996-02-09 1998-11-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein
DE69723531T3 (en) 1996-10-01 2012-09-06 Geron Corp. Catalytic subunit of human telomerase
AU2002363231A1 (en) 2001-10-29 2003-05-12 Baylor College Of Medicine Human telomerase reverse transcriptase as a class-ii restricted tumor-associated antigen
AU2003249357A1 (en) 2002-06-27 2004-01-19 Geron Corporation Cancer vaccine containing cross-species epitopes of telomerase reverse transcriptase
EP1748067A1 (en) * 2005-07-29 2007-01-31 Institut Pasteur Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes
US20090162405A1 (en) 2006-12-14 2009-06-25 Yong Qian Proteinase-engineered cancer vaccine induces immune responses to prevent cancer and to systemically kill cancer cells
CN101522706B (en) * 2006-10-12 2013-09-04 P.安杰莱蒂分子生物学研究所 Telomerase reverse transcriptase fusion protein, nucleotide encoding it and use thereof
WO2009125607A1 (en) * 2008-04-11 2009-10-15 Sapporo Medical University Apoptosis inducer
US20110318380A1 (en) 2008-10-01 2011-12-29 Dako Denmark A/S MHC Multimers in Cancer Vaccines and Immune Monitoring
JP2012039877A (en) 2009-04-10 2012-03-01 Fukuoka Univ Ubiquitin fusion gene, and dna vaccine using the same
RU2539991C2 (en) 2009-12-16 2015-01-27 Кронтек Фарма Аб Injector and device
US10138488B2 (en) 2013-03-28 2018-11-27 Invectys Cancer vaccine for dogs
DK2978445T3 (en) 2013-03-28 2018-10-15 Invectys A CANCERVACCINE FOR CAT
PT3062824T (en) 2013-10-28 2020-02-21 Invectys TELOMERASE CODING DNA VACCINE
CN112851769A (en) * 2014-01-27 2021-05-28 分子模板公司 Deimmunized Shiga toxin subunit A effector polypeptides for use in mammals

Also Published As

Publication number Publication date
BR112016009002B1 (en) 2023-05-02
MX2016005389A (en) 2016-08-03
KR102252756B1 (en) 2021-05-17
EP3666290A1 (en) 2020-06-17
NZ719098A (en) 2022-08-26
US12064474B2 (en) 2024-08-20
ZA201603452B (en) 2020-08-26
US10183065B2 (en) 2019-01-22
EA201690884A1 (en) 2016-11-30
WO2015063117A1 (en) 2015-05-07
AU2014343813B2 (en) 2020-02-27
JP2017502649A (en) 2017-01-26
US20160263204A1 (en) 2016-09-15
EP3062824A1 (en) 2016-09-07
HK1225986A1 (en) 2017-09-22
ES2771862T3 (en) 2020-07-07
IL245186B (en) 2021-02-28
CY1122839T1 (en) 2021-10-29
KR20160111362A (en) 2016-09-26
PL3062824T3 (en) 2020-06-15
CN106061509B (en) 2022-04-08
IL245186A0 (en) 2016-06-30
DK3062824T3 (en) 2020-02-17
EA034928B1 (en) 2020-04-08
US20190000946A1 (en) 2019-01-03
LT3062824T (en) 2020-05-25
MX372778B (en) 2020-06-29
HUE047898T2 (en) 2020-05-28
JP6545162B2 (en) 2019-07-17
PT3062824T (en) 2020-02-21
AU2014343813A1 (en) 2016-05-19
CA2927702C (en) 2022-06-07
SI3062824T1 (en) 2020-04-30
CN106061509A (en) 2016-10-26
RS60232B1 (en) 2020-06-30
BR112016009002A2 (en) 2017-10-03
EP3062824B1 (en) 2019-11-27
HRP20200211T1 (en) 2020-05-15
CA2927702A1 (en) 2015-05-07

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