SG11201603433UA - Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor - Google Patents

Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor

Info

Publication number: SG11201603433UA
Authority: SG; Singapore
Prior art keywords: indoleamine; synthesis; dioxygenase inhibitor; dioxygenase; inhibitor
Prior art date: 2013-11-08

Application number

SG11201603433UA

Inventor

Ming Tao

William Frietze

David J Meloni

Lingkai Weng

Jiacheng Zhou

Yongchun Pan

Original Assignee

Incyte Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-11-08

Filing date

2014-11-07

Publication date

2016-05-30

2014-11-07 Application filed by Incyte Corp filed Critical Incyte Corp

2016-05-30 Publication of SG11201603433UA publication Critical patent/SG11201603433UA/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/06—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/08—1,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Indole Compounds (AREA)

SG11201603433UA 2013-11-08 2014-11-07 Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor SG11201603433UA (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201361901689P	2013-11-08	2013-11-08
PCT/US2014/064531 WO2015070007A1 (en)	2013-11-08	2014-11-07	Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor

Publications (1)

Publication Number	Publication Date
SG11201603433UA true SG11201603433UA (en)	2016-05-30

Family

ID=52023608

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SG11201603433UA SG11201603433UA (en)	2013-11-08	2014-11-07	Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor
SG10201803874PA SG10201803874PA (en)	2013-11-08	2014-11-07	Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SG10201803874PA SG10201803874PA (en)	2013-11-08	2014-11-07	Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor

Country Status (33)

Country	Link
US (3)	US9321755B2 (en)
EP (2)	EP3744715A1 (en)
JP (4)	JP6461953B2 (en)
KR (2)	KR102370067B1 (en)
CN (2)	CN105899498B (en)
AR (2)	AR098343A1 (en)
AU (2)	AU2014346647B2 (en)
BR (2)	BR112016009786B1 (en)
CA (1)	CA2929552C (en)
CL (1)	CL2016001082A1 (en)
CR (2)	CR20190351A (en)
CY (1)	CY1123164T1 (en)
DK (1)	DK3066085T3 (en)
EA (2)	EA201991770A1 (en)
ES (1)	ES2799582T3 (en)
HR (1)	HRP20201089T1 (en)
HU (1)	HUE049337T2 (en)
IL (2)	IL245314B (en)
LT (1)	LT3066085T (en)
ME (1)	ME03792B (en)
MX (2)	MX385075B (en)
MY (1)	MY174254A (en)
PE (2)	PE20160863A1 (en)
PH (2)	PH12019500770B1 (en)
PL (1)	PL3066085T3 (en)
PT (1)	PT3066085T (en)
RS (1)	RS60598B1 (en)
SG (2)	SG11201603433UA (en)
SI (1)	SI3066085T1 (en)
SM (1)	SMT202000381T1 (en)
TW (5)	TWI651311B (en)
UA (1)	UA121741C2 (en)
WO (1)	WO2015070007A1 (en)

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CA2929552C (en)	2013-11-08	2022-05-17	Incyte Holdings Corporation	Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor
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2014
- 2014-11-07 CA CA2929552A patent/CA2929552C/en active Active
- 2014-11-07 CN CN201480071825.0A patent/CN105899498B/en active Active
- 2014-11-07 MY MYPI2016000827A patent/MY174254A/en unknown
- 2014-11-07 TW TW103138838A patent/TWI651311B/en not_active IP Right Cessation
- 2014-11-07 KR KR1020167015077A patent/KR102370067B1/en not_active Expired - Fee Related
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CR20160252A (en)	2016-09-19
CA2929552A1 (en)	2015-05-14
PH12019500770A1 (en)	2020-09-21
PH12016500818B1 (en)	2019-09-18
JP2020019806A (en)	2020-02-06
TW202309014A (en)	2023-03-01
JP6913725B2 (en)	2021-08-04
CR20190351A (en)	2019-10-07
US9321755B2 (en)	2016-04-26
IL245314B (en)	2019-07-31
TWI775079B (en)	2022-08-21
SMT202000381T1 (en)	2020-09-10
US20180244663A1 (en)	2018-08-30
KR102617531B1 (en)	2023-12-27
ME03792B (en)	2021-04-20
MX2019008378A (en)	2019-09-09
JP2017500284A (en)	2017-01-05
PH12019500770B1 (en)	2024-02-02
KR102370067B1 (en)	2022-03-04
IL245314A0 (en)	2016-06-30
AU2014346647A1 (en)	2016-05-26
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EA201690959A1 (en)	2016-08-31
TWI696618B (en)	2020-06-21
RS60598B1 (en)	2020-08-31
CN109810104A (en)	2019-05-28
CN105899498B (en)	2019-01-25
US20150133674A1 (en)	2015-05-14
DK3066085T3 (en)	2020-06-02
SG10201803874PA (en)	2018-07-30
AU2014346647B2 (en)	2018-10-25
PE20220430A1 (en)	2022-03-29
AR133922A2 (en)	2025-11-12
PE20160863A1 (en)	2016-09-03
CY1123164T1 (en)	2021-10-29
EP3066085B1 (en)	2020-05-13
UA121741C2 (en)	2020-07-27
JP6883079B2 (en)	2021-06-09
JP6461953B2 (en)	2019-01-30
BR122020009912B1 (en)	2022-11-01
TW202100523A (en)	2021-01-01
KR20210126157A (en)	2021-10-19
BR112016009786B1 (en)	2021-01-05
KR20160094971A (en)	2016-08-10
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JP2020019805A (en)	2020-02-06
CL2016001082A1 (en)	2016-12-09
TWI651311B (en)	2019-02-21
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US10280157B2 (en)	2019-05-07
US9873688B2 (en)	2018-01-23
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MY174254A (en)	2020-04-01
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AU2019200404B2 (en)	2021-03-04
AR098343A1 (en)	2016-05-26
PT3066085T (en)	2020-07-16
HUE049337T2 (en)	2020-09-28
EA033667B1 (en)	2019-11-14
TW202440069A (en)	2024-10-16
TWI859554B (en)	2024-10-21
HRP20201089T1 (en)	2020-10-30
LT3066085T (en)	2020-06-25
PH12016500818A1 (en)	2016-06-20
MX385075B (en)	2025-03-14
CN105899498A (en)	2016-08-24
MX2016005954A (en)	2016-12-07
AU2019200404A1 (en)	2019-02-07

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