SG11201507673WA - Use of microparticles and endothelial cells with decellularized organs and tissues - Google Patents
Use of microparticles and endothelial cells with decellularized organs and tissuesInfo
- Publication number
- SG11201507673WA SG11201507673WA SG11201507673WA SG11201507673WA SG11201507673WA SG 11201507673W A SG11201507673W A SG 11201507673WA SG 11201507673W A SG11201507673W A SG 11201507673WA SG 11201507673W A SG11201507673W A SG 11201507673WA SG 11201507673W A SG11201507673W A SG 11201507673WA
- Authority
- SG
- Singapore
- Prior art keywords
- microparticles
- tissues
- endothelial cells
- decellularized organs
- decellularized
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3808—Endothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Botany (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361790118P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/026456 WO2014168719A1 (en) | 2013-03-15 | 2014-03-13 | Use of microparticles and endothelial cells with decellularized organs and tissues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201507673WA true SG11201507673WA (en) | 2015-10-29 |
Family
ID=50736149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201507673WA SG11201507673WA (en) | 2013-03-15 | 2014-03-13 | Use of microparticles and endothelial cells with decellularized organs and tissues |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20160030637A1 (en) |
| EP (1) | EP2968672B1 (en) |
| JP (1) | JP6491187B2 (en) |
| KR (2) | KR102282769B1 (en) |
| CN (1) | CN105188786B (en) |
| AU (1) | AU2014251336B2 (en) |
| BR (1) | BR112015023641A2 (en) |
| CA (1) | CA2907144C (en) |
| MX (2) | MX385864B (en) |
| SG (1) | SG11201507673WA (en) |
| WO (1) | WO2014168719A1 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007025233A1 (en) | 2005-08-26 | 2007-03-01 | Regents Of The University Of Minnesota | Decellularization and recellularization of organs and tissues |
| CN103458935B (en) | 2010-09-01 | 2016-08-03 | 明尼苏达大学董事会 | Make tissue or the most cellularised method to improve its portability of organ |
| WO2014110300A1 (en) * | 2013-01-09 | 2014-07-17 | Harvard Apparatus Regenerative Technology | Synthetic scaffolds |
| CN105164250A (en) | 2013-03-15 | 2015-12-16 | 米罗马特里克斯医疗公司 | Use of Perfused Decellularized Liver for Recellularization of Islet Cells |
| WO2016141137A1 (en) | 2015-03-03 | 2016-09-09 | President And Fellows Of Harvard College | Methods of generating functional human tissue |
| CN114672451A (en) | 2015-09-11 | 2022-06-28 | 通用医疗公司 | Regeneration of functional pulmonary vascular beds |
| US11045582B2 (en) * | 2016-02-12 | 2021-06-29 | University Of Ottawa | Decellularised cell wall structures from plants and fungus and use thereof as scaffold materials |
| WO2018048899A1 (en) | 2016-09-06 | 2018-03-15 | Micromatrix Medical Inc. | Use of resected liver serum for whole liver engineering |
| CN108295311A (en) * | 2018-03-07 | 2018-07-20 | 南京市第医院 | A kind of preparation method of temperature sensitive type extracellular matrix of kidney hydrogel |
| CN110343659A (en) * | 2018-04-08 | 2019-10-18 | 生物角（厦门）科技有限公司 | A kind of mescenchymal stem cell complete medium composition |
| GB201807788D0 (en) * | 2018-05-14 | 2018-06-27 | Ucl Business Plc | Method |
| WO2019236622A1 (en) * | 2018-06-04 | 2019-12-12 | Miromatrix Medical Inc. | Methods of liver recellularization |
| US12263275B2 (en) | 2018-06-13 | 2025-04-01 | Miromatrix Medical Inc. | Fistula filler and deployment system |
| CN110732041A (en) * | 2019-10-12 | 2020-01-31 | 广东省人民医院(广东省医学科学院) | decellularized small-caliber intravascular stent and preparation method thereof |
| CN111518755A (en) * | 2020-05-09 | 2020-08-11 | 苏州大学 | A kind of bionic periosteum, periosteum-bone substitute and preparation method |
| CN218059021U (en) * | 2022-09-22 | 2022-12-16 | 舩本诚一 | High-voltage equipment for medical material treatment |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101366978B (en) * | 2008-09-03 | 2013-06-05 | 陕西瑞盛生物科技有限公司 | Fine particle tissue filling material for injection and preparation method thereof |
| ES2650450T3 (en) * | 2010-06-30 | 2018-01-18 | Miromatrix Medical Inc. | Use of perfused decellularized organs for adapted recellularization |
| CN102477172B (en) * | 2010-11-29 | 2016-01-13 | 吴忠仕 | Chitosan-heparin nano particle and remove cytostromatic biomaterial with this nano particle process |
-
2014
- 2014-03-13 CA CA2907144A patent/CA2907144C/en active Active
- 2014-03-13 WO PCT/US2014/026456 patent/WO2014168719A1/en not_active Ceased
- 2014-03-13 EP EP14725270.4A patent/EP2968672B1/en active Active
- 2014-03-13 KR KR1020157029696A patent/KR102282769B1/en active Active
- 2014-03-13 JP JP2016502149A patent/JP6491187B2/en active Active
- 2014-03-13 CN CN201480024707.4A patent/CN105188786B/en active Active
- 2014-03-13 SG SG11201507673WA patent/SG11201507673WA/en unknown
- 2014-03-13 US US14/777,397 patent/US20160030637A1/en not_active Abandoned
- 2014-03-13 BR BR112015023641A patent/BR112015023641A2/en not_active Application Discontinuation
- 2014-03-13 MX MX2015013152A patent/MX385864B/en unknown
- 2014-03-13 KR KR1020217023310A patent/KR102417995B1/en active Active
- 2014-03-13 AU AU2014251336A patent/AU2014251336B2/en active Active
-
2015
- 2015-09-15 MX MX2021010536A patent/MX2021010536A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2968672A1 (en) | 2016-01-20 |
| AU2014251336A1 (en) | 2015-10-29 |
| AU2014251336B2 (en) | 2017-03-16 |
| KR102282769B1 (en) | 2021-07-29 |
| KR102417995B1 (en) | 2022-07-06 |
| MX2021010536A (en) | 2021-10-01 |
| EP2968672B1 (en) | 2019-02-06 |
| JP6491187B2 (en) | 2019-03-27 |
| HK1218888A1 (en) | 2017-03-17 |
| CA2907144C (en) | 2022-10-11 |
| CN105188786A (en) | 2015-12-23 |
| MX2015013152A (en) | 2016-06-21 |
| CN105188786B (en) | 2017-12-26 |
| WO2014168719A1 (en) | 2014-10-16 |
| BR112015023641A2 (en) | 2017-07-18 |
| MX385864B (en) | 2025-03-18 |
| KR20160026840A (en) | 2016-03-09 |
| JP2016513654A (en) | 2016-05-16 |
| KR20210095722A (en) | 2021-08-02 |
| WO2014168719A8 (en) | 2015-04-23 |
| US20160030637A1 (en) | 2016-02-04 |
| CA2907144A1 (en) | 2014-10-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG11201507673WA (en) | Use of microparticles and endothelial cells with decellularized organs and tissues | |
| IL272325B (en) | Hematopoietic stem cells and modified non-effector T cells and their uses | |
| IL268976B (en) | Prostamide-containing intraocular implants and methods of use thereof | |
| IL240252B (en) | Solid substrates to encourage cell and tissue growth | |
| IL244296A0 (en) | Cell penetrating conjugates and methods of use thereof | |
| ME03747B (en) | Compositions for improving cell viability and methods of use thereof | |
| DK2994173T3 (en) | Wound healing and tissue engineering | |
| EP2951348A4 (en) | Tissue having high strength and low modulus | |
| PL3004833T3 (en) | Improvements in and relating to tissue sampling | |
| EP2958492A4 (en) | Tissue expanders, implants, and methods of use | |
| ZA201504824B (en) | ANTI- INTEGRIN ß1 ANTIBODY COMPOSITIONS AND METHODS OF USE THEREOF | |
| SG11201504771RA (en) | Host cells and methods of use | |
| IL245272B (en) | Pif-transfected cells and methods of use | |
| HUE036094T2 (en) | Cells expressing Th1 characteristics and cytolytic properties | |
| EP2968374A4 (en) | Methods and compositions for enhancing oxygen levels in tissues | |
| IL245214B (en) | Post-natal hematopoetic endothelial cells and their isolation and use | |
| ZA201602151B (en) | Therapy with cells from human placenta and hematopoietic cells | |
| IL233826A0 (en) | Β-arrestin effectors and compositions and methods of use thereof | |
| GB201304038D0 (en) | Treated cells and therapeutic uses | |
| HRP20190041T1 (en) | INSTALLATIONS TO ENCOURAGE THE INTEGRATION OF SOFT AND SOLID TISSUE | |
| GB2519072B (en) | Composition comprising collagen and honey | |
| EP3006561A4 (en) | Peripheral blood stem cells with improved angiogenic properties and use thereof |