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SG11201507483PA - Methods for treating crohn's disease using an anti-il23 antibody - Google Patents

Methods for treating crohn's disease using an anti-il23 antibody

Info

Publication number
SG11201507483PA
SG11201507483PA SG11201507483PA SG11201507483PA SG11201507483PA SG 11201507483P A SG11201507483P A SG 11201507483PA SG 11201507483P A SG11201507483P A SG 11201507483PA SG 11201507483P A SG11201507483P A SG 11201507483PA SG 11201507483P A SG11201507483P A SG 11201507483PA
Authority
SG
Singapore
Prior art keywords
antibody
disease
methods
treating crohn
crohn
Prior art date
Application number
SG11201507483PA
Inventor
Wei-Jian Pan
Wayne Tsuji
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG11201507483PA publication Critical patent/SG11201507483PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
SG11201507483PA 2013-03-15 2014-02-25 Methods for treating crohn's disease using an anti-il23 antibody SG11201507483PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361789976P 2013-03-15 2013-03-15
PCT/US2014/018308 WO2014143540A1 (en) 2013-03-15 2014-02-25 Methods for treating crohn's disease using an anti-il23 antibody

Publications (1)

Publication Number Publication Date
SG11201507483PA true SG11201507483PA (en) 2015-10-29

Family

ID=50236361

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201507483PA SG11201507483PA (en) 2013-03-15 2014-02-25 Methods for treating crohn's disease using an anti-il23 antibody
SG10201805015TA SG10201805015TA (en) 2013-03-15 2014-02-25 Methods for treating crohn's disease using an anti-il23 antibody

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201805015TA SG10201805015TA (en) 2013-03-15 2014-02-25 Methods for treating crohn's disease using an anti-il23 antibody

Country Status (17)

Country Link
US (5) US20160031983A1 (en)
EP (2) EP2968486A1 (en)
JP (4) JP2016516686A (en)
KR (1) KR20150128859A (en)
CN (1) CN105307675A (en)
AP (1) AP2015008801A0 (en)
AU (1) AU2014228553B2 (en)
CA (1) CA2906384A1 (en)
CL (1) CL2015002724A1 (en)
EA (1) EA201591579A1 (en)
HK (1) HK1220605A1 (en)
IL (2) IL241343A0 (en)
NZ (1) NZ712294A (en)
PH (1) PH12015502133A1 (en)
SG (2) SG11201507483PA (en)
TN (1) TN2015000402A1 (en)
WO (1) WO2014143540A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3244B1 (en) 2009-10-26 2018-03-08 Amgen Inc Proteins bind to human IL-23 antigens
EP2635601B1 (en) 2010-11-04 2016-07-20 Boehringer Ingelheim International GmbH Anti-il-23 antibodies
WO2013165791A1 (en) 2012-05-03 2013-11-07 Boehringer Ingelheim International Gmbh Anti-il-23p19 antibodies
EP3172339A1 (en) 2014-07-24 2017-05-31 Boehringer Ingelheim International GmbH Biomarkers useful in the treatment of il-23a related diseases
US10059763B2 (en) 2014-09-03 2018-08-28 Boehringer Ingelheim International Gmbh Compound targeting IL-23A and TNF-alpha and uses thereof
AR102417A1 (en) 2014-11-05 2017-03-01 Lilly Co Eli ANTI-TNF- / ANTI-IL-23 BIESPECTIFIC ANTIBODIES
IL307578A (en) 2015-02-04 2023-12-01 Boehringer Ingelheim Int Methods for treating inflammatory diseases
AR103782A1 (en) * 2015-02-26 2017-05-31 Genentech Inc INTEGRINE b7 ANTAGONISTS AND METHODS OF TREATMENT OF CROHN'S DISEASE
TWI811716B (en) * 2015-09-18 2023-08-11 德商百靈佳殷格翰國際股份有限公司 Methods of treating inflammatory diseases
US10765724B2 (en) * 2016-03-29 2020-09-08 Janssen Biotech, Inc. Method of treating psoriasis with increased interval dosing of anti-IL12/23 antibody
EP3526252A2 (en) * 2016-10-14 2019-08-21 Boehringer Ingelheim International GmbH Methods of treating diseases with il-23a antibody
SG11202100185VA (en) * 2018-07-13 2021-02-25 Astrazeneca Collaboration Ventures Llc Treating ulcerative colitis with brazikumab
TWI850365B (en) 2019-04-22 2024-08-01 美商美國禮來大藥廠 Methods of treating crohn's disease
AU2020332371A1 (en) * 2019-08-21 2022-03-03 Astrazeneca Collaboration Ventures, Llc Use of brazikumab to treat crohn's disease
EP4125849A4 (en) * 2020-03-31 2024-04-17 ChemoCentryx, Inc. COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE INVOLVING CCR9 INHIBITOR AND ANTI-IL-23 BLOCKING ANTIBODIES
CN111956606B (en) * 2020-08-31 2021-05-14 江苏荃信生物医药有限公司 Low viscosity liquid formulations comprising high concentrations of anti-human interleukin 23 monoclonal antibodies

Family Cites Families (24)

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US6171586B1 (en) 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
CO4810232A1 (en) 1997-07-25 1999-06-30 Schering Corp MAMMALIAN CYTOKINES AND THEIR CODING SEQUENCES
ES2410406T3 (en) 2005-06-30 2013-07-01 Janssen Biotech, Inc. Anti-IL-23 antibodies, compositions, procedures and uses
EP1937721B1 (en) 2005-08-25 2010-07-28 Eli Lilly And Company Anti-il-23 antibodies
US20070050011A1 (en) 2005-08-26 2007-03-01 Medlogics Device Corporation Lumen-supporting stents and methods for creating lumen-supporting stents with various open/closed designs
HUE032131T2 (en) 2005-08-31 2017-09-28 Merck Sharp & Dohme Engineered anti-il-23 antibodies
US7686047B2 (en) * 2005-11-04 2010-03-30 Roger Cleveland Golf Co., Inc. Golf club cover
EP3219328B1 (en) * 2005-12-29 2020-06-17 Janssen Biotech, Inc. Human anti-il-23 antibodies, compositions, method and uses
AU2007260787A1 (en) 2006-06-13 2007-12-21 Zymogenetics, Inc IL-17 and IL-23 antagonists and methods of using the same
ATE554791T1 (en) 2007-02-23 2012-05-15 Schering Corp GENETICALLY ENGINEERED ANTI-IL-23P19 ANTIBODIES
EP2064242A1 (en) * 2007-02-23 2009-06-03 Schering Corporation Engineered anti-il-23p19 antibodies
AR068723A1 (en) 2007-10-05 2009-12-02 Glaxo Group Ltd PROTEIN THAT JOINS ANTIGENS THAT JOINS HUMAN IL-23 AND ITS USES
US20090117289A1 (en) * 2007-10-09 2009-05-07 Enerize Corporation Method and apparatus for deposition of thin film materials for energy storage devices
WO2009082624A2 (en) 2007-12-10 2009-07-02 Zymogenetics, Inc. Antagonists of il-17a, il-17f, and il-23 and methods of using the same
TWI461210B (en) * 2008-03-18 2014-11-21 Abbvie Inc Methods for treating psoriasis
WO2010027766A1 (en) 2008-08-27 2010-03-11 Schering Corporation Lyophilized formulatons of engineered anti-il-23p19 antibodies
WO2010115786A1 (en) 2009-04-01 2010-10-14 Glaxo Group Limited Anti-il-23 immunoglobulins
WO2010142534A1 (en) * 2009-05-27 2010-12-16 Ablynx Nv Biparatopic protein constructs directed against il-23
JO3244B1 (en) * 2009-10-26 2018-03-08 Amgen Inc Proteins bind to human IL-23 antigens
WO2011088120A1 (en) 2010-01-15 2011-07-21 Amgen Inc. Antibody formulation and therapeutic regimens
US9127057B2 (en) 2010-07-20 2015-09-08 Teva Pharmaceuticals Ausralia Pty Ltd Anti-IL-23 heterodimer specific antibodies
CN103154031A (en) * 2010-10-08 2013-06-12 诺华有限公司 Methods of treating psoriasis using il-17 antagonists
EP2635601B1 (en) 2010-11-04 2016-07-20 Boehringer Ingelheim International GmbH Anti-il-23 antibodies
JP2014506132A (en) * 2011-01-07 2014-03-13 アッヴィ・インコーポレイテッド Anti-IL-12 / IL-23 antibody and use thereof

Also Published As

Publication number Publication date
US20160031983A1 (en) 2016-02-04
EP3693007A1 (en) 2020-08-12
US20170218062A1 (en) 2017-08-03
AU2014228553A1 (en) 2015-10-08
JP2021107397A (en) 2021-07-29
US20200017581A1 (en) 2020-01-16
CL2015002724A1 (en) 2016-03-28
NZ712294A (en) 2020-04-24
CA2906384A1 (en) 2014-09-18
AU2014228553B2 (en) 2019-01-24
JP2016516686A (en) 2016-06-09
CN105307675A (en) 2016-02-03
EA201591579A1 (en) 2016-01-29
IL241343A0 (en) 2015-11-30
JP2023012516A (en) 2023-01-25
SG10201805015TA (en) 2018-07-30
WO2014143540A1 (en) 2014-09-18
US20200283517A1 (en) 2020-09-10
KR20150128859A (en) 2015-11-18
AP2015008801A0 (en) 2015-10-31
PH12015502133A1 (en) 2016-01-25
US20180327490A1 (en) 2018-11-15
EP2968486A1 (en) 2016-01-20
HK1220605A1 (en) 2017-05-12
IL275092A (en) 2020-07-30
TN2015000402A1 (en) 2017-01-03
JP2020073470A (en) 2020-05-14

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