SG11201505918TA - Immobilized transaminases and process for making and using immobilized transaminase - Google Patents
Immobilized transaminases and process for making and using immobilized transaminaseInfo
- Publication number
- SG11201505918TA SG11201505918TA SG11201505918TA SG11201505918TA SG11201505918TA SG 11201505918T A SG11201505918T A SG 11201505918TA SG 11201505918T A SG11201505918T A SG 11201505918TA SG 11201505918T A SG11201505918T A SG 11201505918TA SG 11201505918T A SG11201505918T A SG 11201505918TA
- Authority
- SG
- Singapore
- Prior art keywords
- immobilized
- making
- transaminases
- transaminase
- immobilized transaminase
- Prior art date
Links
- 102000003929 Transaminases Human genes 0.000 title 2
- 108090000340 Transaminases Proteins 0.000 title 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/087—Acrylic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361770366P | 2013-02-28 | 2013-02-28 | |
| PCT/US2014/017898 WO2014133928A1 (en) | 2013-02-28 | 2014-02-24 | Immobilized transaminases and process for making and using immobilized transaminase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201505918TA true SG11201505918TA (en) | 2015-09-29 |
Family
ID=51428712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201505918TA SG11201505918TA (en) | 2013-02-28 | 2014-02-24 | Immobilized transaminases and process for making and using immobilized transaminase |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9523107B2 (en) |
| EP (1) | EP2961838B1 (en) |
| CN (1) | CN105073983B (en) |
| SG (1) | SG11201505918TA (en) |
| WO (1) | WO2014133928A1 (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109251925A (en) * | 2017-07-14 | 2019-01-22 | 上海蓝木化工有限公司 | A kind of preparation and its application of fixed on ion exchange resin transaminase |
| CN110129306A (en) * | 2018-02-08 | 2019-08-16 | 广东东阳光药业有限公司 | Immobilized transaminase and its application |
| CN108689984B (en) * | 2018-05-02 | 2019-09-20 | 淮阴工学院 | A kind of biosynthesis method and intermediate of ticagrelor intermediate |
| WO2021108957A1 (en) * | 2019-12-02 | 2021-06-10 | 吉林凯莱英医药化学有限公司 | Co-immobilized enzyme, preparation method therefor and application thereof |
| CN112430632B (en) * | 2020-11-18 | 2022-09-13 | 上海合全药物研发有限公司 | Preparation method of 2- ((trans) -4-aminocyclohexyl) isopropanol |
| CN113481254B (en) * | 2021-06-29 | 2023-05-26 | 台州酶易生物技术有限公司 | Preparation method of sitagliptin intermediate |
| CN113430184B (en) * | 2021-06-29 | 2022-04-01 | 台州酶易生物技术有限公司 | Transaminase and application thereof in preparation of sitagliptin |
| CN115232807A (en) * | 2022-09-01 | 2022-10-25 | 沈阳农业大学 | A thermogel-assisted mesoporous silica cross-linking enzyme aggregation carrier and its embedded DFA synthase |
| CN117467733B (en) * | 2023-12-27 | 2024-03-12 | 北京元延医药科技股份有限公司 | High chiral purity sitagliptin and method for preparing same by using immobilized transaminase |
| CN118063351B (en) * | 2024-04-18 | 2024-06-28 | 北京元延医药科技股份有限公司 | Green synthesis of chiral beta amino acids using biological enzymes and immobilized aminotransferase used |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020132295A1 (en) | 1996-02-09 | 2002-09-19 | Short Jay M. | Enzymes having transaminase and aminotransferase activity and methods of use thereof |
| AR043515A1 (en) | 2003-03-19 | 2005-08-03 | Merck & Co Inc | PROCEDURE TO PREPARE CHIRAL DERIVATIVES BETA AMINO ACIDS BY ASYMMETRIC HYDROGENATION |
| WO2004085624A2 (en) | 2003-03-24 | 2004-10-07 | Diversa Corporation | Transaminases, deaminases and aminomutases and compositions and methods for enzymatic detoxification |
| JO2625B1 (en) | 2003-06-24 | 2011-11-01 | ميرك شارب اند دوم كوربوريشن | Phosphoric acid salt of a dipeptidyl peptidase-IV inhibitor |
| ES2587572T3 (en) | 2005-04-26 | 2016-10-25 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin stereoisomers and their precursors |
| PL2238242T3 (en) | 2008-01-03 | 2015-06-30 | Basf Enzymes Llc | Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them |
| CN102405281B (en) | 2009-02-26 | 2015-05-13 | 科德克希思公司 | Transaminase biocatalysts |
| ES2644992T3 (en) * | 2009-06-22 | 2017-12-01 | Codexis, Inc. | Transaminase reactions |
| JP5927178B2 (en) * | 2011-03-11 | 2016-06-01 | 株式会社カネカ | Modified aminotransferase, gene thereof, and method for producing optically active amino compound using them |
| US9587229B2 (en) * | 2011-06-24 | 2017-03-07 | Merck Sharp & Dohme Corp. | Immobilized transaminases and process for making and using immobilized transaminase |
| JP6436541B2 (en) * | 2013-02-28 | 2018-12-12 | コデクシス, インコーポレイテッド | Engineered transaminase polypeptides for industrial biocatalysis |
-
2014
- 2014-02-24 US US14/767,949 patent/US9523107B2/en active Active
- 2014-02-24 EP EP14757359.6A patent/EP2961838B1/en active Active
- 2014-02-24 WO PCT/US2014/017898 patent/WO2014133928A1/en not_active Ceased
- 2014-02-24 SG SG11201505918TA patent/SG11201505918TA/en unknown
- 2014-02-24 CN CN201480010959.1A patent/CN105073983B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN105073983B (en) | 2018-09-18 |
| US9523107B2 (en) | 2016-12-20 |
| US20150368682A1 (en) | 2015-12-24 |
| CN105073983A (en) | 2015-11-18 |
| EP2961838B1 (en) | 2018-04-18 |
| WO2014133928A1 (en) | 2014-09-04 |
| EP2961838A1 (en) | 2016-01-06 |
| EP2961838A4 (en) | 2016-07-13 |
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