SG11201500425PA - Extended-release levetiracetam and method of preparation - Google Patents
Extended-release levetiracetam and method of preparationInfo
- Publication number
- SG11201500425PA SG11201500425PA SG11201500425PA SG11201500425PA SG11201500425PA SG 11201500425P A SG11201500425P A SG 11201500425PA SG 11201500425P A SG11201500425P A SG 11201500425PA SG 11201500425P A SG11201500425P A SG 11201500425PA SG 11201500425P A SG11201500425P A SG 11201500425PA
- Authority
- SG
- Singapore
- Prior art keywords
- extended
- preparation
- release levetiracetam
- levetiracetam
- release
- Prior art date
Links
- 238000013265 extended release Methods 0.000 title 1
- HPHUVLMMVZITSG-ZCFIWIBFSA-N levetiracetam Chemical compound CC[C@H](C(N)=O)N1CCCC1=O HPHUVLMMVZITSG-ZCFIWIBFSA-N 0.000 title 1
- 229960004002 levetiracetam Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261680789P | 2012-08-08 | 2012-08-08 | |
| PCT/US2013/053097 WO2014025593A1 (en) | 2012-08-08 | 2013-07-31 | Extended-release levetiracetam and method of preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201500425PA true SG11201500425PA (en) | 2015-04-29 |
Family
ID=50066329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201500425PA SG11201500425PA (en) | 2012-08-08 | 2013-07-31 | Extended-release levetiracetam and method of preparation |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20140044780A1 (en) |
| EP (1) | EP2882292A4 (en) |
| CN (1) | CN104619175A (en) |
| AU (1) | AU2013299938A1 (en) |
| CA (1) | CA2877134A1 (en) |
| HK (1) | HK1208130A1 (en) |
| SG (1) | SG11201500425PA (en) |
| TW (1) | TW201410267A (en) |
| WO (1) | WO2014025593A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105142623A (en) | 2013-03-15 | 2015-12-09 | 艾吉因生物股份有限公司 | Methods and compositions for improving cognitive function |
| GB201411196D0 (en) * | 2014-06-24 | 2014-08-06 | Dupont Nutrition Biosci Aps | Composition and use thereof |
| US10159648B2 (en) * | 2015-05-22 | 2018-12-25 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| CN107167401B (en) * | 2017-05-18 | 2020-01-07 | 湖南洞庭药业股份有限公司 | Levetiracetam sustained-release tablet pharmaceutical composition and quality control and preparation method thereof |
| JP7264711B2 (en) * | 2019-04-26 | 2023-04-25 | 東和薬品株式会社 | Method for producing pharmaceutical composition containing levetiracetam |
| MX2024001034A (en) | 2021-07-23 | 2024-02-23 | Neuraxpharm Pharmaceuticals S L | Multiparticulate pharmaceutical composition. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050250838A1 (en) * | 2004-05-04 | 2005-11-10 | Challapalli Prasad V | Formulation for sustained delivery |
| EA014249B1 (en) * | 2005-01-27 | 2010-10-29 | Алембик Лимитед | Formulation of extended release levetiracetam |
| US8431156B2 (en) * | 2005-02-22 | 2013-04-30 | Sun Pharma Advanced Research Company Ltd. | Pharmaceutical composition |
| WO2008062446A2 (en) * | 2006-09-14 | 2008-05-29 | Alembic Limited | An extended release composition of levetiracetam, which exhibits no adverse food effect |
| US20120003307A1 (en) * | 2007-11-29 | 2012-01-05 | Ranbaxy Laboratories Limited | Levetiracetam controlled release composition |
| US20100323016A1 (en) * | 2008-07-18 | 2010-12-23 | Biljana Nadjsombati | Modified release formulation and methods of use |
| WO2010026467A2 (en) * | 2008-09-04 | 2010-03-11 | Torrent Pharmaceuticals Ltd. | Controlled release dosage form of high solubility active ingredient |
| CN101647789B (en) * | 2009-09-01 | 2011-08-17 | 天津药物研究院药业有限责任公司 | Levetiracetam sustained-release pellet capsule preparation |
-
2013
- 2013-07-31 EP EP13827438.6A patent/EP2882292A4/en not_active Withdrawn
- 2013-07-31 SG SG11201500425PA patent/SG11201500425PA/en unknown
- 2013-07-31 WO PCT/US2013/053097 patent/WO2014025593A1/en not_active Ceased
- 2013-07-31 AU AU2013299938A patent/AU2013299938A1/en not_active Abandoned
- 2013-07-31 CN CN201380041625.6A patent/CN104619175A/en active Pending
- 2013-07-31 CA CA2877134A patent/CA2877134A1/en not_active Abandoned
- 2013-07-31 HK HK15108813.1A patent/HK1208130A1/en unknown
- 2013-08-05 US US13/958,933 patent/US20140044780A1/en not_active Abandoned
- 2013-08-08 TW TW102128580A patent/TW201410267A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2882292A4 (en) | 2016-04-06 |
| HK1208130A1 (en) | 2016-02-26 |
| CA2877134A1 (en) | 2014-02-13 |
| US20140044780A1 (en) | 2014-02-13 |
| TW201410267A (en) | 2014-03-16 |
| WO2014025593A1 (en) | 2014-02-13 |
| AU2013299938A1 (en) | 2015-01-22 |
| EP2882292A1 (en) | 2015-06-17 |
| CN104619175A (en) | 2015-05-13 |
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