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SG11201408489PA - Target detection and signal amplification - Google Patents

Target detection and signal amplification

Info

Publication number
SG11201408489PA
SG11201408489PA SG11201408489PA SG11201408489PA SG11201408489PA SG 11201408489P A SG11201408489P A SG 11201408489PA SG 11201408489P A SG11201408489P A SG 11201408489PA SG 11201408489P A SG11201408489P A SG 11201408489PA SG 11201408489P A SG11201408489P A SG 11201408489PA
Authority
SG
Singapore
Prior art keywords
international
nsw
methods
detection
sydney
Prior art date
Application number
SG11201408489PA
Inventor
Simon Mark Bone
Alison Velyian Todd
Timothy Daniel Meehan
Original Assignee
Speedx Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012902551A external-priority patent/AU2012902551A0/en
Application filed by Speedx Pty Ltd filed Critical Speedx Pty Ltd
Publication of SG11201408489PA publication Critical patent/SG11201408489PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6823Release of bound markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/9005Enzymes with nucleic acid structure; e.g. ribozymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 27 December 2013 (27.12.2013) WIPOIPCT (10) International Publication Number WO 2013/188912 A1 (51) International Patent Classification: C12Q 1/68 (2006.01) CI20 1/44 (2006.01) C12N 9/22 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: (30) Priority Data: 2012902551 2012903462 2013202354 PCT/AU2013/000651 18 June 2013 (18.06.2013) English English AU AU AU 18 June 2012 (18.06.2012) 10 August 2012 (10.08.2012) 3 April 2013 (03.04.2013) (71) Applicant: SPEEDX PTY LTD [AU/AU]; Suite G16, Na­ tional Innovation Centre, Australian Technology Park, 4 Cornwallis Street, Eveleigh, NSW 2015 (AU). (72) Inventors: BONE, Simon Mark; 2/56 Grosvenor Cres­ cent, Summer Hill, NSW 2130 (AU). TODD, Alison Ve- lyian; 10 Coneill Place, Glebe, NSW 2037 (AU). MEE- HAN, Timothy Daniel; 434 W 221 -229 Sydney Park Rd, Erskineville, NSW (AU). (74) Agent: SPRUSON & FERGUSON; GPO Box Sydney, New South Wales 2001 (AU). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) CJ i-H o\ 00 00 i-H o CJ (54) Title: TARGET DETECTION AND SIGNAL AMPLIFICATION (57) Abstract: The present invention relates to compositions and methods for the detection of target molecules, and the amplifica­ tion of detectable signals generated by detection assays. More specifically, the present invention relates to methods utilizing catalytic nucleic acid enzymes to generate and/or amplify signal indicative a of the presence of target molecules (e.g. nucleic acids and pro - teins), and compositions for use in the methods.
SG11201408489PA 2012-06-18 2013-06-18 Target detection and signal amplification SG11201408489PA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2012902551A AU2012902551A0 (en) 2012-06-18 Target detection and signal amplification
AU2012903462A AU2012903462A0 (en) 2012-08-10 Target detection and signal amplification
AU2013202354A AU2013202354A1 (en) 2012-06-18 2013-04-03 Target detection and signal amplification
PCT/AU2013/000651 WO2013188912A1 (en) 2012-06-18 2013-06-18 Target detection and signal amplification

Publications (1)

Publication Number Publication Date
SG11201408489PA true SG11201408489PA (en) 2015-01-29

Family

ID=49767935

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201408489PA SG11201408489PA (en) 2012-06-18 2013-06-18 Target detection and signal amplification

Country Status (11)

Country Link
US (1) US9725757B2 (en)
EP (1) EP2861770B1 (en)
JP (1) JP6336443B2 (en)
CN (1) CN104540965B (en)
AU (2) AU2013202354A1 (en)
CA (1) CA2876919C (en)
IL (1) IL236363A0 (en)
IN (1) IN2015DN00194A (en)
NZ (1) NZ629701A (en)
SG (1) SG11201408489PA (en)
WO (1) WO2013188912A1 (en)

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CN114354912A (en) * 2021-12-29 2022-04-15 东南大学 Quantum dot micelle spherical nucleic acid sensor and preparation method thereof and sensor prepared from quantum dot micelle spherical nucleic acid sensor2+Applications in assays
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Also Published As

Publication number Publication date
JP6336443B2 (en) 2018-06-06
IL236363A0 (en) 2015-02-26
NZ629701A (en) 2016-03-31
EP2861770A1 (en) 2015-04-22
EP2861770A4 (en) 2015-12-23
AU2013277929B2 (en) 2015-07-16
AU2013202354A1 (en) 2014-01-16
IN2015DN00194A (en) 2015-06-12
CA2876919A1 (en) 2013-12-27
AU2013277929A1 (en) 2015-01-22
WO2013188912A1 (en) 2013-12-27
HK1205202A1 (en) 2015-12-11
CN104540965B (en) 2019-06-04
CA2876919C (en) 2021-09-14
EP2861770B1 (en) 2018-01-31
US9725757B2 (en) 2017-08-08
CN104540965A (en) 2015-04-22
JP2015523864A (en) 2015-08-20
US20160083785A1 (en) 2016-03-24

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