SG11201407945SA - Cladosporium peptides - Google Patents
Cladosporium peptidesInfo
- Publication number
- SG11201407945SA SG11201407945SA SG11201407945SA SG11201407945SA SG11201407945SA SG 11201407945S A SG11201407945S A SG 11201407945SA SG 11201407945S A SG11201407945S A SG 11201407945SA SG 11201407945S A SG11201407945S A SG 11201407945SA SG 11201407945S A SG11201407945S A SG 11201407945SA
- Authority
- SG
- Singapore
- Prior art keywords
- oxford
- international
- seq
- circassia
- science park
- Prior art date
Links
- 241000222290 Cladosporium Species 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 241000223600 Alternaria Species 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0002—Fungal antigens, e.g. Trichophyton, Aspergillus, Candida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01138—Mannitol 2-dehydrogenase (NADP+) (1.1.1.138)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01003—Aldehyde dehydrogenase (NAD+) (1.2.1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01011—Phosphopyruvate hydratase (4.2.1.11), i.e. enolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Toxicology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
Abstract
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 5 December 2013 (05.12.2013) WIPOIPCT (10) International Publication Number WO 2013/179044 A2 (51) International Patent Classification: C07K14/37 ( 2006.01) A61K 39/35 (2006.01) CI2N 9/64 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/GB2013/051440 30 May 2013 (30.05.2013) English English (30) Priority Data: 1209862.0 1 June 2012 (01.06.2012) GB (71) Applicant: CIRCASSIA LIMITED [GB/GB]; The Ox ford Science Park, Oxford, Oxfordshire OX4 4GA (GB). (72) Inventors: HAFNER, Roderick Peter; Circassia Ltd, Magdalen Centre, The Oxford Science Park, Oxford, Ox fordshire OX4 4GA (GB). LAIDLER, Paul; Circassia Ltd, Magdalen Centre, The Oxford Science Park, Oxford, Ox fordshire OX4 4GA (GB). HICKEY, Pascal; Circassia Ltd, Magdalen Centre, The Oxford Science Park, Oxford, Oxfordshire OX4 4GA (GB). LARCHE, Mark; Depart ment of Medicine HSC, 4H20 McMaster University, 1200 Main Street, West Hamilton, Ontario L8N 3Z5 (CA). (74) Agent: WOODS, Geoffrey Corlett; 14 South Square, Gray's Inn, London, Greater London WC1R 5JJ (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — without international search report and to be republished upon receipt of that report (Rule 48.2(g)) — with sequence listing part of description (Rule 5.2(a)) CJ •t •t o o\ l> i-H cn i-H o CJ o & (54) Title: CLADOSPORIUM PEPTIDES (57) Abstract: Polypeptides which may be used for preventing or treating allergy to moulds of the Cladosporium and/or Alternaria genus, have up to 30 amino acids in length and comprise: (I) the amino acid sequence: (a) GGYKAAVRPTMLE (SEQ ID NO : 35; Cla35), (b) AE V YQKLK SLTKK (SEQ ID NO: 31; Clal6), (c) VAITYASRAQGAE (SEQ ID NO: 32; Cla25), (d) GHHFKERGT - GSLVIT (SEQ ID NO: 33; Cla26), or (e) ANYTQTKTVSIRL (SEQ ID NO: 34; Cla29); or (II) a T cell epitope-containing variant sequence which is a said amino acid sequence (I) having up to six amino acid modifications, each of which is independently a dele - tion, substitution or insertion.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1209862.0A GB201209862D0 (en) | 2012-06-01 | 2012-06-01 | Cladosporium peptides |
| PCT/GB2013/051440 WO2013179044A2 (en) | 2012-06-01 | 2013-05-30 | Cladosporium peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201407945SA true SG11201407945SA (en) | 2014-12-30 |
Family
ID=46582262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201407945SA SG11201407945SA (en) | 2012-06-01 | 2013-05-30 | Cladosporium peptides |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9850281B2 (en) |
| EP (1) | EP2855514A2 (en) |
| JP (1) | JP2015520171A (en) |
| KR (1) | KR20150016622A (en) |
| CN (1) | CN104507960A (en) |
| AU (1) | AU2013269327A1 (en) |
| BR (1) | BR112014029834A2 (en) |
| CA (1) | CA2875131A1 (en) |
| CL (1) | CL2014003289A1 (en) |
| EA (1) | EA201492270A1 (en) |
| GB (2) | GB201209862D0 (en) |
| HK (1) | HK1202554A1 (en) |
| IL (1) | IL235842A0 (en) |
| MX (1) | MX2014014460A (en) |
| SG (1) | SG11201407945SA (en) |
| WO (1) | WO2013179044A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA49157A (en) * | 2014-12-23 | 2021-06-02 | Immatics Biotechnologies Gmbh | NEW PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY FOR HEPATOCELLULAR CARCINOMA (HCC) AND OTHER CANCERS |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT400722B (en) * | 1993-08-27 | 1996-03-25 | Biomay Prod & Handel | RECOMBINANT CLADOSPORIUM HERBARUM ALLERGENS |
| AT401181B (en) | 1994-11-02 | 1996-07-25 | Biomay Prod & Handel | RECOMBINANT DNA MOLECULES |
| AT403166B (en) * | 1995-03-02 | 1997-11-25 | Biomay Prod & Handel | RECOMBINANT DNA MOLECULES ENCODING POLYPEPTIDES THAT HAVE THE ANTIGENSITY OF THE ALLERGENS CLAH8 AND CLAH12 |
| CA2217173C (en) | 1997-11-25 | 2008-04-01 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Health | Isolation of a cdna clone encoding a subunit of the alternaria alternata major allergen alt a 1, and production of recombinant protein thereof |
| US7247441B2 (en) | 2002-03-28 | 2007-07-24 | Biomay Produktions- Und Handels-Aktienge Sellschaft | Nucleic acid sequence and protein in addition to polypeptides coding for mannitol dehydrogenases or parts thereof and the production and use thereof in diagnosis and therapy |
| CN103272227B (en) | 2007-08-15 | 2014-12-10 | 切尔卡西亚有限公司 | Peptides for desensibilization against allergens |
| CN101178406A (en) | 2007-12-05 | 2008-05-14 | 杭州浙大生物基因工程有限公司 | Allergen specificity antibody IgE ELISA detection reagent box and method of producing the same |
| EP2331124A1 (en) * | 2008-08-15 | 2011-06-15 | Circassia Limited | T-cell antigen peptide from allergen for stimulation of il-10 production |
| CN101387643A (en) | 2008-10-20 | 2009-03-18 | 杭州浙大生物基因工程有限公司 | Multichannel allergen rapid detection kit and method for making same |
| CN101393215A (en) | 2008-11-17 | 2009-03-25 | 杭州浙大生物基因工程有限公司 | Multichannel attractive type allergen rapid detection kit and method for making same |
| GB0821806D0 (en) | 2008-11-28 | 2009-01-07 | Circassia Ltd | Compositions with reduced dimer formation |
| GB201002559D0 (en) | 2010-02-15 | 2010-03-31 | Circassia Ltd | Birch peptides for vaccine |
| CN102212531A (en) | 2010-04-02 | 2011-10-12 | 复旦大学 | Preparation method and application of recombinant Cladosporium herbarum allergen Cla h8 protein |
| MX2013003817A (en) | 2010-10-15 | 2013-05-01 | Alk Abello As | Suppression of a hypersensitivity immune response with unrelated antigen derived from allergen source material. |
| AU2013216983A1 (en) * | 2012-02-07 | 2014-09-18 | La Jolla Institute For Allergy And Immunology | Epitopes from allergen proteins and methods and uses for immune response modulation |
-
2012
- 2012-06-01 GB GBGB1209862.0A patent/GB201209862D0/en not_active Ceased
-
2013
- 2013-05-30 BR BR112014029834A patent/BR112014029834A2/en not_active IP Right Cessation
- 2013-05-30 SG SG11201407945SA patent/SG11201407945SA/en unknown
- 2013-05-30 WO PCT/GB2013/051440 patent/WO2013179044A2/en not_active Ceased
- 2013-05-30 CN CN201380040588.7A patent/CN104507960A/en active Pending
- 2013-05-30 EA EA201492270A patent/EA201492270A1/en unknown
- 2013-05-30 KR KR1020147037164A patent/KR20150016622A/en not_active Withdrawn
- 2013-05-30 JP JP2015514590A patent/JP2015520171A/en active Pending
- 2013-05-30 EP EP13726838.9A patent/EP2855514A2/en not_active Withdrawn
- 2013-05-30 MX MX2014014460A patent/MX2014014460A/en unknown
- 2013-05-30 US US14/403,462 patent/US9850281B2/en not_active Expired - Fee Related
- 2013-05-30 GB GB1422973.6A patent/GB2518092A/en not_active Withdrawn
- 2013-05-30 AU AU2013269327A patent/AU2013269327A1/en not_active Abandoned
- 2013-05-30 HK HK15102838.5A patent/HK1202554A1/en unknown
- 2013-05-30 CA CA2875131A patent/CA2875131A1/en not_active Abandoned
-
2014
- 2014-11-23 IL IL235842A patent/IL235842A0/en unknown
- 2014-12-01 CL CL2014003289A patent/CL2014003289A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2855514A2 (en) | 2015-04-08 |
| IL235842A0 (en) | 2015-01-29 |
| WO2013179044A2 (en) | 2013-12-05 |
| HK1202554A1 (en) | 2015-10-02 |
| KR20150016622A (en) | 2015-02-12 |
| BR112014029834A2 (en) | 2017-07-25 |
| GB201209862D0 (en) | 2012-07-18 |
| GB2518092A (en) | 2015-03-11 |
| JP2015520171A (en) | 2015-07-16 |
| CN104507960A (en) | 2015-04-08 |
| US9850281B2 (en) | 2017-12-26 |
| AU2013269327A1 (en) | 2014-12-18 |
| WO2013179044A3 (en) | 2014-03-06 |
| CA2875131A1 (en) | 2013-12-05 |
| US20150218215A1 (en) | 2015-08-06 |
| MX2014014460A (en) | 2015-02-12 |
| EA201492270A1 (en) | 2015-09-30 |
| CL2014003289A1 (en) | 2015-05-22 |
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