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SG11201406105UA - Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample - Google Patents

Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample

Info

Publication number
SG11201406105UA
SG11201406105UA SG11201406105UA SG11201406105UA SG11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA SG 11201406105U A SG11201406105U A SG 11201406105UA
Authority
SG
Singapore
Prior art keywords
immunofluorescence
fluorescent
nucleic acid
acid analysis
single sample
Prior art date
Application number
SG11201406105UA
Inventor
Antti E Seppo
Fiona Ginty
Kevin B Kenny
David Lavan Henderson
Michael J Gerdes
Moreno Adriana I Larriera
Xiaofeng Liu
Alex D Corwin
Stephen E Zingelewicz
Thomas Ha
Natalie R Jun
Ainura Kyshtoobayeve
Denise A Hollman-Hewgley
Ying Li
Original Assignee
Clarient Diagnostic Services Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clarient Diagnostic Services Inc filed Critical Clarient Diagnostic Services Inc
Publication of SG11201406105UA publication Critical patent/SG11201406105UA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG11201406105UA 2012-03-30 2013-03-21 Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample SG11201406105UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261618132P 2012-03-30 2012-03-30
PCT/US2013/033249 WO2013148448A1 (en) 2012-03-30 2013-03-21 Immunoflu0rescence and fluorescent-based nucleic acid analysis on a single sample

Publications (1)

Publication Number Publication Date
SG11201406105UA true SG11201406105UA (en) 2014-10-30

Family

ID=48050953

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201406105UA SG11201406105UA (en) 2012-03-30 2013-03-21 Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample

Country Status (12)

Country Link
US (2) US20150065371A1 (en)
EP (1) EP2831591B1 (en)
JP (1) JP6225163B2 (en)
KR (1) KR20140142715A (en)
CN (1) CN104520713A (en)
AU (1) AU2013240127B2 (en)
CA (1) CA2867508C (en)
IN (1) IN2014DN07531A (en)
NZ (1) NZ630091A (en)
RU (1) RU2014137129A (en)
SG (1) SG11201406105UA (en)
WO (1) WO2013148448A1 (en)

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DK3111221T4 (en) 2014-02-24 2022-04-19 Ventana Med Syst Inc Methods, kits and systems for scoring the immune response to cancer by simultaneous detection of CD3, CD8, CD20 and FOXP3
CN104980558B (en) * 2014-04-01 2019-01-01 中国移动通信集团公司 A kind of method, apparatus of information processing, mobile phone pet client and mobile terminal
US20150286887A1 (en) * 2014-04-07 2015-10-08 Massachusetts Institute Of Technology Use of Microparticle Additives to Simultaneously Enable Artifact-Free Image Registration, Auto-Focusing, and Chromatic Aberration Correction in Microscopy
US20170242235A1 (en) * 2014-08-18 2017-08-24 Viewsiq Inc. System and method for embedded images in large field-of-view microscopic scans
EP3227684B1 (en) * 2014-12-03 2019-10-02 Isoplexis Corporation Analysis and screening of cell secretion profiles
US11353448B2 (en) 2015-02-13 2022-06-07 California Institute Of Technology Methods and compositions for quantifying metabolites and proteins from single cells
US10706536B2 (en) * 2015-07-20 2020-07-07 Min Xu Photon structure and chemometrics pathologic system
EP3396375B1 (en) * 2015-12-24 2021-08-04 Konica Minolta, Inc. Image processing device and program
CN107419001A (en) * 2016-05-23 2017-12-01 益善生物技术股份有限公司 BRCA1, PTEN gene unconventionality detection kit and detection method
JP6231709B1 (en) * 2016-05-31 2017-11-15 シスメックス株式会社 Fluorescence image analyzer and analysis method
CN109313798B (en) * 2016-06-10 2022-04-01 豪夫迈·罗氏有限公司 Method and image processing system for generating analog digital brightfield IHC or ISH images
CN106290878A (en) * 2016-09-10 2017-01-04 天津大学 The preparation method of pancreatic tumour mark CA242 immuno-chromatographic test paper strip based on quantum dot
EP3510398A1 (en) 2016-09-12 2019-07-17 Isoplexis Corporation System and methods for multiplexed analysis of cellular and other immunotherapeutics
CN109791157B (en) * 2016-09-26 2022-06-07 贝克顿迪金森公司 Measuring protein expression using reagents with barcoded oligonucleotide sequences
US11493508B2 (en) 2016-11-11 2022-11-08 IsoPlexis Corporation Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells
US11525783B2 (en) 2016-11-22 2022-12-13 IsoPlexis Corporation Systems, devices and methods for cell capture and methods of manufacture thereof
CN112601950B (en) * 2018-08-22 2023-07-28 仪景通株式会社 Image processing device, camera system, working method of image processing device, and working program of image processing device
US10921223B2 (en) * 2018-10-12 2021-02-16 Shenzhen Prs Limited Process record slide for staining and method of using the same
CN110498858B (en) * 2019-07-26 2024-01-23 深圳市达科为生物工程有限公司 Method for dynamically detecting secretion condition of single-cell exoprotein
KR20220110589A (en) * 2019-12-17 2022-08-08 어플라이드 머티어리얼스, 인코포레이티드 Systems and Methods for Acquisition and Processing of Multiple Fluorescence In Situ Hybridization Images
JP2023524815A (en) * 2020-05-07 2023-06-13 アドヴァンスド セル ダイアグノスティクス,インコーポレイテッド Method and kit for simultaneous detection of target nucleic acid and target protein
WO2022020340A1 (en) * 2020-07-20 2022-01-27 Akoya Biosciences, Inc. Processing and imaging tissue samples
CN116113983A (en) * 2020-08-13 2023-05-12 文塔纳医疗系统公司 Automated Identification of Necrotic Regions in Digital Images of Multiplex Immunofluorescence Stained Tissue
EP4491742A3 (en) * 2020-09-18 2025-05-21 10x Genomics, Inc. Sample handling apparatus and image registration methods
CN112415198B (en) * 2020-11-20 2022-11-11 四川大学华西医院 Application of GP1BB detection reagent in preparation of lung cancer screening kit
CN113310963B (en) * 2021-05-31 2023-12-01 四川大学华西医院 An improved immunofluorescence detection method for neutrophil NETs
JP2024545363A (en) 2021-11-16 2024-12-05 ソティオ・バイオテック・インコーポレイテッド Treatment of Patients with Myxoid/Round Cell Liposarcoma
CA3243342A1 (en) * 2022-01-28 2023-08-03 University Of Southern California Identifying non-disease patients using a disease related assay and analysis in the liquid biopsy
US20250216394A1 (en) * 2022-01-28 2025-07-03 University Of Southern California Liquid biopsy analytes to define cancer stages

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Also Published As

Publication number Publication date
EP2831591A1 (en) 2015-02-04
US20150065371A1 (en) 2015-03-05
AU2013240127A1 (en) 2014-10-02
JP2015514212A (en) 2015-05-18
US20250102507A1 (en) 2025-03-27
CA2867508C (en) 2021-05-18
NZ630091A (en) 2016-03-31
WO2013148448A1 (en) 2013-10-03
EP2831591B1 (en) 2019-05-08
IN2014DN07531A (en) 2015-04-24
JP6225163B2 (en) 2017-11-01
KR20140142715A (en) 2014-12-12
CN104520713A (en) 2015-04-15
AU2013240127B2 (en) 2018-07-12
RU2014137129A (en) 2016-05-27
CA2867508A1 (en) 2013-10-03

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