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SG11201406865PA - Assays, methods and apparatus for assessing rna disruption - Google Patents

Assays, methods and apparatus for assessing rna disruption

Info

Publication number
SG11201406865PA
SG11201406865PA SG11201406865PA SG11201406865PA SG11201406865PA SG 11201406865P A SG11201406865P A SG 11201406865PA SG 11201406865P A SG11201406865P A SG 11201406865PA SG 11201406865P A SG11201406865P A SG 11201406865PA SG 11201406865P A SG11201406865P A SG 11201406865PA
Authority
SG
Singapore
Prior art keywords
assays
methods
rna disruption
assessing rna
assessing
Prior art date
Application number
SG11201406865PA
Inventor
Baoqing Guo
Kenneth Pritzker
Amadeo Mark Parissenti
Laura Pritzker
Mu Zhu
Xiaohui Wang
Stacey Santi
Rashmi Narendrula
Original Assignee
Rna Diagnostics Inc
Kenneth Pritzker
Amadeo Mark Parissenti
Laura Pritzker
Mu Zhu
Xiaohui Wang
Stacey Santi
Rashmi Narendrula
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rna Diagnostics Inc, Kenneth Pritzker, Amadeo Mark Parissenti, Laura Pritzker, Mu Zhu, Xiaohui Wang, Stacey Santi, Rashmi Narendrula filed Critical Rna Diagnostics Inc
Publication of SG11201406865PA publication Critical patent/SG11201406865PA/en

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44791Microapparatus
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/142Toxicological screening, e.g. expression profiles which identify toxicity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
SG11201406865PA 2012-04-24 2013-04-24 Assays, methods and apparatus for assessing rna disruption SG11201406865PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261637676P 2012-04-24 2012-04-24
US201361806222P 2013-03-28 2013-03-28
PCT/CA2013/000408 WO2013159200A1 (en) 2012-04-24 2013-04-24 Assays, methods and apparatus for assessing rna disruption

Publications (1)

Publication Number Publication Date
SG11201406865PA true SG11201406865PA (en) 2014-11-27

Family

ID=49482066

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201406865PA SG11201406865PA (en) 2012-04-24 2013-04-24 Assays, methods and apparatus for assessing rna disruption

Country Status (10)

Country Link
US (2) US11031096B2 (en)
EP (2) EP3907294A1 (en)
JP (1) JP6279549B2 (en)
CN (1) CN104640998B (en)
AU (1) AU2013252445B2 (en)
BR (1) BR112014026440A8 (en)
CA (1) CA2871195C (en)
HK (1) HK1207887A1 (en)
SG (1) SG11201406865PA (en)
WO (1) WO2013159200A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6279549B2 (en) 2012-04-24 2018-02-14 アールエヌエー、ダイアグノスティックス、インコーポレイテッドRna Diagnostics Inc. Assays, methods and apparatus for assessing RNA disruption
HK1215875A1 (en) 2012-12-03 2016-09-23 Rna Diagnostics Inc. Methods and kits for monitoring response to radiation therapies in cancer
US10731222B2 (en) 2013-10-04 2020-08-04 Rna Diagnostics Inc. RNA disruption assay for predicting survival
WO2016069539A1 (en) * 2014-10-27 2016-05-06 Helix Nanotechnologies, Inc. Systems and methods of screening with a molecule recorder
US10855748B2 (en) 2015-09-30 2020-12-01 IntegenX, Inc. Command center
RU2018127709A (en) * 2016-01-22 2020-02-25 Отрэйсис, Инк. SYSTEMS AND METHODS FOR IMPROVING DIAGNOSTICS OF DISEASES
CN110291388B (en) * 2017-03-10 2022-08-23 株式会社岛津制作所 Electrophoresis analysis method, electrophoresis analysis device, and electrophoresis analysis program
CN108253894B (en) * 2018-02-06 2020-08-18 中原内配集团股份有限公司 Detection method for surface convex structure of cylinder sleeve
JP7533245B2 (en) * 2021-01-27 2024-08-14 株式会社島津製作所 Microchip electrophoresis device

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251247B1 (en) 1998-04-01 2001-06-26 Hitachi Chemical Co., Ltd. Detection of degradation of RNA using microchannel electrophoresis
US6873915B2 (en) 2001-08-24 2005-03-29 Surromed, Inc. Peak selection in multidimensional data
CA2480175A1 (en) 2002-04-02 2003-10-16 Aclara Biosciences, Inc. Multiplexed assays using electrophoretically separated molecular tags
EP1573636A2 (en) * 2002-07-01 2005-09-14 Institut Pasteur System, method, device, and computer program product for extraction, gathering, manipulation, and analysis of peak data from an automated sequencer
AU2003288621A1 (en) 2002-12-31 2004-07-22 Pfizer Products Inc. Rna bioassay
EP1457573B1 (en) 2003-03-04 2006-06-21 PamGene B.V. Method for integrated nucleic acid integrity assessment and analysis
DE10315581B4 (en) 2003-04-05 2007-06-28 Agilent Technologies, Inc. (n.d.Ges.d.Staates Delaware), Palo Alto Method for quality determination of RNA samples
WO2005090609A1 (en) 2004-03-18 2005-09-29 Arcturus Bioscience, Inc. Determination of rna quality
US8131473B1 (en) 2004-05-20 2012-03-06 Metabolon, Inc. Data analysis methods for locating entities of interest within large, multivariable datasets
ES2384107T3 (en) 2004-11-05 2012-06-29 Genomic Health, Inc. Molecular indicators of breast cancer prognosis and treatment response prediction
EP1772522A1 (en) 2005-10-04 2007-04-11 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Control of preservation by biomarkers
WO2007053491A2 (en) 2005-10-28 2007-05-10 The Trustees Of Columbia University In The City Of New York Method and kit for evaluating rna quality
EP2198296B1 (en) 2007-09-05 2015-11-11 Laurentian University Method of using tumour rna integrity to measure response to chemotherapy in cancer patients
US9150909B2 (en) 2008-08-29 2015-10-06 Bio-Rad Laboratories, Inc. Determination of the integrity of RNA
CN102308004A (en) 2008-10-30 2012-01-04 卡里斯生命科学卢森堡控股有限责任公司 Methods for Assessing RNA Motifs
HK1199072A1 (en) 2011-08-10 2015-06-19 Laurentian University Of Sudbury Diagnostic methods and kits for monitoring response to chemotherapy in ovarian cancer
JP6279549B2 (en) 2012-04-24 2018-02-14 アールエヌエー、ダイアグノスティックス、インコーポレイテッドRna Diagnostics Inc. Assays, methods and apparatus for assessing RNA disruption
HK1215875A1 (en) 2012-12-03 2016-09-23 Rna Diagnostics Inc. Methods and kits for monitoring response to radiation therapies in cancer

Also Published As

Publication number Publication date
CN104640998A (en) 2015-05-20
CA2871195C (en) 2023-01-10
US20220028489A1 (en) 2022-01-27
AU2013252445B2 (en) 2018-01-18
BR112014026440A2 (en) 2017-06-27
US20150154350A1 (en) 2015-06-04
JP2015519887A (en) 2015-07-16
EP2841604A4 (en) 2016-01-06
WO2013159200A1 (en) 2013-10-31
AU2013252445A8 (en) 2015-01-15
EP2841604A1 (en) 2015-03-04
BR112014026440A8 (en) 2018-01-16
US11031096B2 (en) 2021-06-08
HK1207887A1 (en) 2016-02-12
JP6279549B2 (en) 2018-02-14
EP3907294A1 (en) 2021-11-10
CA2871195A1 (en) 2013-10-31
CN104640998B (en) 2018-08-14
AU2013252445A1 (en) 2014-12-04

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